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Wearable devices to support Parkinson's disease research

Posted: Published on August 14th, 2014

The Michael J Fox was created in 2000, after the actor was diagnosed with Parkinson's The devices collect more than 300 observations per second from each patient on measurable features of Parkinson's, including slowness of movement, tremor and sleep quality. This data can be transmitted to the researchers' computers over the internet in real time 24 hours a day, seven days a week helping them to detect patterns and make new discoveries. "Data science and wearable computing hold the potential to transform our ability to capture and objectively measure patients' actual experience of disease, with unprecedented implications for Parkinson's drug development, diagnosis and treatment," said Todd Sherer, chief executive of The Michael J Fox Foundation. The partnership follows a trial of the technology earlier this year. Sixteen Parkinson's patients and nine control volunteers wore the devices during two clinic visits and at home continuously over four days. "I know that many doctors tell their patients to keep a log to track their Parkinson's," Bret Parker, 46, of New York, who is living with Parkinson's and participated in the study. "I am not a compliant patient on that front. I pay attention to my Parkinson's, but it's not everything I am … Continue reading

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Wife: Robin Williams had Parkinson's

Posted: Published on August 14th, 2014

STORY HIGHLIGHTS (CNN) -- Robin Williams was sober but was struggling with depression, anxiety and the early stages of Parkinson's disease when he died, his widow said Thursday. The diagnosis of the progressive illness was "an additional fear and burden in his life," a person familiar with Williams' family told CNN on Thursday. Williams was found dead in his Northern California home Monday from what investigators suspect was a suicide by hanging. While fans and friends have looked for answers to why the 63-year-old comedy icon would take his own life, his wife, Susan Schneider, issued a written statement about Williams' health that he had kept a secret. "Since his passing, all of us who loved Robin have found some solace in the tremendous outpouring of affection and admiration for him from the millions of people whose lives he touched," Schneider said. "His greatest legacy, besides his three children, is the joy and happiness he offered to others, particularly to those fighting personal battles. Comedic actor Robin Williams dies Comedic actor Robin Williams dies Comedic actor Robin Williams dies Comedic actor Robin Williams dies Continued here: Wife: Robin Williams had Parkinson's … Continue reading

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Michael J Fox Foundation uses big data to monitor Parkinson's disease

Posted: Published on August 14th, 2014

The Michael J Fox Foundation is using big data techniques in an attempt to cure Parkinson's disease, in collaboration with chip manufacturer Intel. The two organisations will join forces in a research study using a new big data analytics platform designed to detect patterns in data collected from wearable sensors on Parkinson's sufferers. "Nearly 200 years after Parkinson's disease was first described by Dr James Parkinson in 1817, we are still subjectively measuring Parkinson's disease largely the same way doctors did then," said Todd Sherer, PhD, CEO of The Michael J Fox Foundation. "Data science and wearable computing hold the potential to transform our ability to capture and objectively measure patients' actual experience of disease, with unprecedented implications for Parkinson's drug development, diagnosis and treatment," he added. "The variability in Parkinson's symptoms creates unique challenges in monitoring progression of the disease," said Diane Bryant, senior vice president and general manager of Intel's Data Center Group. "Emerging technologies can not only create a new paradigm for measurement of Parkinson's, but as more data is made available to the medical community, it may also point to currently unidentified features of the disease that could lead to new areas of research," she said. … Continue reading

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Parkinson's and depression: A deadly combination for Robin Williams?

Posted: Published on August 14th, 2014

Robin Williams wife Susan Schneider released a statement Thursday revealing that the late actor had recently been diagnosed with Parkinsons disease, prior to taking his life earlier this week. Those who suffer with Parkinsons disease produce too little dopamine in parts of the brain. The deficiency of dopamine leads to problems with movement, including rigid muscles and tremors. Parkinsons disease and major depression sometimes coexist and, when they do, they can make one another worse. People with both conditions, for example, tend to be more plagued with anxiety than either, alone. And people with both conditions can have even more trouble with movement than those with either, alone. The ability to concentrate may decline precipitously. Interestingly (and, perhaps, tragically) a medication called ropinirole, which stimulates dopamine receptors in the brain, not only helps many people with early stage Parkinsons disease, but also helps some people with depression, when more traditional medications (like Prozac or Cymbalta) havent done an adequate job. If Williams had had the time to be adequately treated for his Parkinsons disease, it might have also helped his symptoms of depression. Psychologically, of course, being diagnosed with Parkinsons disease, while already battling a history of substance dependence and … Continue reading

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Intel's Big Data to Fight Parkinson's Disease

Posted: Published on August 14th, 2014

NEW YORK Intel is collaborating with the Michael J. Fox Foundation (MJFF) to use big data analytics in research and treatment for Parkinson's disease. A multi-phase study used the specially created analytics platform to detect patterns in participant data collected from wearable technologies used to monitor symptoms. In conjunction with New Yorks Mount Sinai Hospital and Tel Aviv Medical Center, Intel and MJFF used an undisclosed smartwatch tethered to a smartphone to track physiological symptoms such as tremors from 16 Parkinson's patients and nine control volunteers. Participants wore the devices during two clinic visits and at home continuously over four days as an alternative to traditional tracking methods. Data was then correlated with clinical observations and patient diaries to gauge the devices accuracy and develop algorithms to measure disease progression. Weve gathered 300 events per second, or 1 GB of data per patient per day. Thats as much data per month as the entire Library of Congress, said Diane Bryant, senior vice president and general manager of Intels Data Center Group, at a web conference. She believes big data will play a significant role in all industries but especially healthcare. "The life impacting opportunity created by harnessing and mining the … Continue reading

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Children with cerebral palsy being helped all over the world thanks to Mirror campaign

Posted: Published on August 14th, 2014

A Mirror campaign to highlight Tory cuts to vital operations for cerebral palsy sufferers has helped children around the world. The case of Ben Baddeley - whose selective dorsal rhizotomy (SDR) treatment was paid for by our readers - has led to families as far afield as Holland, America, New Zealand, China, Vietnam and New Zealand getting help. His parents Amy and Gary told how a series of articles to highlight the benefits of the treatment has seen thousands of people follow his story. And our campaign helped bring about not just a Government U-turn in the UK to fund the operations, as well as giving hope to cerebral palsy sufferers across the globe. Our readers have now helped to raise almost 30,000 for Ben and, after his second and final life-changing operation, he will continue to undergo vital 150-a-session physio three times a week to help him to walk. His family, of Silverdale, Staffs, has just released video footage charting his remarkable progress - and will be writing to the hundreds of our readers to thank every one personally, with pictures of Ben before the treatment, and afterwards. Amy, 29, said: "We now have 4,280 people following Ben's progress … Continue reading

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Cerebral palsy: 'To take care of others, you must start with yourself'

Posted: Published on August 14th, 2014

Cerebral palsy does not only affect one person, it alters the lives of the family as well. It took a while to adjust to the implications of Cathy Naidoo's* cerebral palsy, but the family soon slipped into the routines of everyday life. (Madelene Cronj, M&G) We try to live as normal of a life as possible, says Charlene Naidoo*, sitting on the edge of the black leather couch in the living room of her Mayfair home in Johannesburg. But when we go to the shops people stare. Children will come and stand by her wheelchair and just stare at her. Charlenes smile is sad. Sometimes I look at other mothers and daughters that age walking in the mall and shopping, and I think that could have been us. The hands of her 16-year-old daughter Cathy* are turned sideways, her knees inward and her limbs are rigid. Cathy has cerebral palsy, a physical disability that affects movement, posture and co-ordination, according to the United Cerebral Palsy Association of South Africa. It is caused by damage to the part of the brain that controls motor function. It took Charlene* and her husband Roy* years to come to terms with their daughters diagnosis.(Photos:Madelene … Continue reading

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Concussions & Mild Traumatic Brain Injuries Are the Focus of Two Upcoming Conferences at LifeBridge Health

Posted: Published on August 14th, 2014

Contact Information Available for logged-in reporters only Newswise Baltimore, MD The Sinai Rehabilitation Center and the Comprehensive Sports Concussion Program at the Sandra and Malcolm Berman Brain & Spine Institute have announced their fall conferences, both of which will focus on concussions and mild traumatic brain injuries. On Friday, October 24, the Sinai Rehabilitation Center will hold its 12th annual fall series, entitled, The Evolving Landscape in Treatment of Mild Traumatic Brain Injury: New Evidence in Concussion Management. Talks by Kevin Crutchfield, M.D., director of the Comprehensive Sports Concussion Program at LifeBridge Health, and Martha S. Burns, Ph.D., CCC-SLP, from Northwestern University will highlight the program. Crutchfield will discuss Concussion: Complex Diagnosis, Effective Treatment, and Related Controversies, and Burns will discuss Linking Neuroscience to Clinical Practice in three sessions: Early Cognitive Rehabilitation following mTBI; Treatment of Prefrontal Lobe DeficitsExecutive Function, Self-Awareness, and Social Skills; and Intervention Strategies for Post-Injury Changes in Memory and Emotional Control. On Saturday, October 25, the Comprehensive Sports Concussion Program at the Sandra and Malcolm Berman Brain & Spine Institute will conduct its 3rd annual conference, entitled Bridging the Gap: Return to Learn. The aim of this conference is to provide current information about correctly recognizing … Continue reading

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Bancroft expands into Mount Laurel

Posted: Published on August 14th, 2014

MOUNT LAUREL Thanks to a $2 million grant, Bancroft, a nonprofit that assists children and adults with a variety of disabilities, is turning a dilapidated warehouse into an 18,000-square-foot structure for brain injury victims. The grant was provided by Lynda and Stewart Resnick through their Resnick Foundation, based in Los Angeles, according to Bancroft, based in nearby Haddonfield. kAm%96 8C2?E H:== 36 FD65 E@ D64FC6 255:E:@?2= 4FDE@>:K65 DA246[ AC@4FC6 DE2E6@7E962CE 6BF:A>6?E[ 2?5 DEC6?8E96? AC@8C2>D 2E E96 q2?4C@7E #6D?:4< r6?E6C @? r9FC49 #@25] xE H:== 92G6 2 DA64:2= 7@4FD @? D6CG:?8 G6E6C2?D]k^Am kAm(6 2C6 D@ 6I4:E65 23@FE E96 A@DD:3:=:E:6D 4C62E65 3J E9:D 86?6C@FD 8C2?E] (6 2C6 =@@62?D E@ AC@G:56 >F49?66565 D6CG:46D E@ :?5:G:5F2=D H:E9 3C2:? :?;FC:6D 2?5 E96:C =@G65 @?6D[ 6DA64:2==J G6E6C2?D[ D2:5 rJ?E9:2 q@J6C[ 6I64FE:G6 5:C64E@C @7 q2?4C@7E qC2:? x?;FCJ #6923:=:E2E:@?[ 😕 2 DE2E6>6?E]k^Am kAm~? (65?6D52J 27E6C?@@?[ 4@?EC24E@CD 4@?E:?F65 H@C< @? E96 @=5 3F:=5:?8 E92E H:== 36 4@>A=6E65 3J E96 72==]k^Am kAm%96 5@?2E:@? H:== 6?23=6 q2?4C@7E qC2:? x?;FCJ #6923:=:E2E:@? E@ 6IA2?5 D6CG:46D E@ @FEA2E:6?ED[ :?4=F5:?8 G6E6C2?D H:E9 EC2F>2E:4 3C2:? :?;FC:6D[ @77:4:2=D D2:5]k^Am kAm(6 2C6 566A=J 8C2E67F= E@ E96 #6D?:4< u@F?52E:@? 7@C DF49 2 86?6C@FD D9@H @7 DFAA@CE 7@C @FC 3C2:? :?;FCJ AC@8C2>[ D2:5 |:496==6 v@==2A2==:[ 49:67 56G6=@A>6?E @77:46C 2E q2?4C@7E[ … Continue reading

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Opexa Therapeutics Reports Second Quarter 2014 Financial Results and Provides Corporate Update

Posted: Published on August 14th, 2014

Recent highlights include: We are pleased to close the first half of 2014 in a strong position to continue developing Tcelna for the treatment of patients with Secondary Progressive Multiple Sclerosis, saidNeil K. Warma, Opexas President and Chief Executive Officer. Completion of enrollment in the Phase IIb Abili-T trial during this past quarter represents an important milestone in the development of our personalized immunotherapy for the Secondary Progressive MS community. We remain committed to our goal in developing Tcelna for this patient population. As ofJune 30, 2014, Opexas cash and cash equivalents totaled approximately$16,214,690 and the Companys monthly burn rate for the six months endingJune 2014was approximately$1.2 million. Based on the current clinical activities for the Abili-T trial, Opexa believes it has sufficient liquidity to support its current clinical activities for the Abili-T trial and general operations to sustain itself into the fourth quarter of 2015. Second Quarter Financial Results Opexa reported revenue of$307,686for the three months endedJune 30, 2014, compared to$348,837for the three months endedJune 30, 2013. The revenue is related to the recognized portion of the$5 millionupfront payment received from Merck Serono in conjunction with the Option and License Agreement entered into between Opexa and Merck Serono duringFebruary … Continue reading

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