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Stem cells show promise for stroke in pilot study

Posted: Published on August 8th, 2014

A stroke therapy using stem cells extracted from patients' bone marrow has shown promising results in the first trial of its kind in humans. Five patients received the treatment in a pilot study conducted by doctors at Imperial College Healthcare NHS Trust and scientists at Imperial College London. The therapy was found to be safe, and all the patients showed improvements in clinical measures of disability. The findings are published in the journal Stem Cells Translational Medicine. It is the first UK human trial of a stem cell treatment for acute stroke to be published. The therapy uses a type of cell called CD34+ cells, a set of stem cells in the bone marrow that give rise to blood cells and blood vessel lining cells. Previous research has shown that treatment using these cells can significantly improve recovery from stroke in animals. Rather than developing into brain cells themselves, the cells are thought to release chemicals that trigger the growth of new brain tissue and new blood vessels in the area damaged by stroke. The patients were treated within seven days of a severe stroke, in contrast to several other stem cell trials, most of which have treated patients after … Continue reading

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Center for Autism and Related Disorders Opens Manhattan Treatment Center for Adults and Children with Autism

Posted: Published on August 8th, 2014

New York (PRWEB) August 06, 2014 Center for Autism and Related Disorders (CARD) today announced the opening of its new treatment center in Manhattan, N.Y. for adults and children with autism spectrum disorder (ASD). CARD has over 25 centers worldwide and is known for leading the way in the successful treatment of autism, achieving measurable results for each client, which in some cases includes recovery. CARD provides a variety of services using the evidence-based principles of ABA to treat the delays and challenges commonly associated with ASD. ABA is the only scientifically validated treatment for ASD, and research shows that it is most effective when delivered early and at a high level of intensity. This will be the third CARD location in the state of New York, located at 14 E. 109th Street, Manhattan, N.Y. 10029. We are thrilled to partner with the David Arthur Foundation to bring CARD services to New York City, said Dr. Doreen Granpeesheh, founder and CEO of CARD. We are working together to ensure that every individual diagnosed with autism has access to top quality treatment for a brighter future. Services include CARD integrated services for adults, center-based treatment, home-based services and supervision, parent training, … Continue reading

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Rowan University Prof Researches Parents' Impact on Their Children with Autism

Posted: Published on August 8th, 2014

Contact Information Available for logged-in reporters only Newswise Though neither she nor any family members have been diagnosed with autism, Dr. MaryLouise Kerwin lives with the condition virtually every day. The New Jersey Governors Council for Medical Research and Treatment of Autism awarded a $394,200 two-year grant to Kerwin, the chairperson of the Department of Psychology at Rowan University, Glassboro, N.J., to research parent-implemented treatment for autism in young children. She is in the second year of the Rowan Autism Parent Program, working with co-investigator Dr. Michelle Soreth, an associate professor of psychology at Rowan, and 17 undergraduate and graduate students and graduate alumni on the pilot study. According to Autism Speaks, about 1 in 88 American children are on the autism spectrum10 times as many as 40 years ago. Individuals with autism manifest the condition in different waysand to various extremesand receive various types of treatment for the brain disorder. One aspect of Kerwins research focuses on assessing a treatment on the market that parents and schools districts use but which has never been evaluated. It could be effective. It could not be effective. We dont know. One goal is to evaluate that treatment, said Kerwin, who earned a … Continue reading

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Blood-oxytocin levels in normal range in children with autism, study finds

Posted: Published on August 8th, 2014

PUBLIC RELEASE DATE: 4-Aug-2014 Contact: Erin Digitale digitale@stanford.edu 650-724-9175 Stanford University Medical Center Autism does not appear to be solely caused by a deficiency of oxytocin, but the hormone's universal ability to boost social function may prove useful in treating a subset of children with the developmental disorder, according to new findings from the Stanford University School of Medicine and Lucile Packard Children's Hospital Stanford. Low levels of oxytocin, a hormone involved in social functioning, have for years been suspected of causing autism. Prior research seeking a link has produced mixed results. Now, in the largest-ever study to test the purported connection, the range of blood oxytocin levels has been shown to be the same in children with autism as that observed in two comparison groups: children with autistic siblings and children without autistic siblings. In other words, similar numbers of children with low, medium and high oxytocin levels were found in all three groups. A paper describing the new findings will be published online Aug. 4 in Proceedings of the National Academy of Sciences. Although autism was not directly linked to oxytocin deficiency, the Stanford team found that higher oxytocin levels were linked to better social functioning in all … Continue reading

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National Autism Conference opens up discussions on important topics

Posted: Published on August 8th, 2014

This week, Penn State hosted the National Autism Conference, which is designed to inform students, professionals, educators, families and others about autism spectrum disorders. This is the 18th year the university has hosted the four-day conference at the Penn Stater Conference Center Hotel. Penn State holds various conferences and speaker series throughout the year at facilities like the conference center and the Nittany Lion Inn, but with this one usually in the summer, and not in walking distance to the main campus, its important to remember that it does happen and helps many people. Autism typically enters the media conversation these days with discussions about controversies including the cause of the disorder. However, much of this conference focused on treatment and how to help people adapt to a lifestyle on the autism spectrum. Living and dealing with it on a daily and lifelong basis are the important pieces that experts, families and students come to this conference for. Its an important part of our university to bring these experts and resources together in order to better understand a topic as complicated as the autism spectrum. Many of the basic facets of everyday life are made exponentially more challenging with something … Continue reading

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Hope for future treatment of thousands of stroke sufferers from stem cells

Posted: Published on August 8th, 2014

"So we said what about the other 90 per cent?" The team targeted patients who had suffered massive strokes involving a blood clot in the blood vessel in the middle of the brain. Typically there is a high mortality rate in these patients and those who survive are often severely disabled, are unable to walk, talk, feed or dress themselves. The experimental procedure was carried out on five patients aged between 40 and 70, all of whom showed improvement over the following six months and three were living independently. More than 152,000 people suffer a stroke in England per year and the research team said that the new procedure could eventually help most of them. Dr Madina Kara, a neuroscientist at The Stroke Association, said: Previous studies have shown that a type of stem cell, called CD34+ cells, shows promise to aid stroke recovery. These latest results suggest that this type of treatment could be administered safely and were looking forward to seeing the outcomes of further studies to see exactly how they are aiding recovery. This is one of the most exciting recent developments in stroke research; however, its still early days in stem cell research but the findings … Continue reading

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Speedy Delivery of Clot-Busting Drug Helps Stroke Patients Avoid Disability

Posted: Published on August 8th, 2014

WEDNESDAY, Aug. 6, 2014 (HealthDay News) Another study confirms that "time is brain" when treating stroke patients with a powerful clot-busting drug, tPA. Prompt treatment with tissue plasminogen activator (tPA, also known as alteplase) "is a very effective means of limiting the degree of disability in stroke patients," study co-author Dr. Jonathan Emberson, of University of Oxford in the U.K., said in a news release from the journal The Lancet. The study, published in the journal on Aug. 5, also reinforces the idea that the quicker that patients can get tPA, the better. One U.S. expert agreed. "The analysis reiterates the importance of patients going to the ER immediately at the time of developing acute neurological symptoms that could be due to a stroke," said Dr. Rafael Alexander Ortiz, director of interventional neuroradiology and stroke at Lenox Hill Hospital in New York City. Clot-busting drugs are used to treat people who have suffered an ischemic stroke, which occurs when a clot blocks blood flow to the brain. In the study, Emberson's team looked at data from more than 6,700 stroke patients who took part in nine clinical trials involving tPA. The likelihood of a good outcome -- defined as no … Continue reading

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Working to get Maddy to US

Posted: Published on August 8th, 2014

Greg Best was browsing Facebook one night when he saw a story about five-year-old Maddy Dorrington. Maddy has cerebral palsy and spastic diplegia, meaning she can't walk, balance or carry out daily activities independently. But there is hope that one day she will be able to walk on her own and be independent after being accepted for surgery at St Louis Children's Hospital in Missouri, USA. Mum Gemma has to raise $140,000 to get them from Torbay to Missouri and be able to pay for the physiotherapy treatment needed for a year afterwards. Her story struck a chord with Greg because Maddy is close in age to his own daughter Mackenzie, who is almost 4. "Seeing (Mackenzie) grow up every day healthy is an absolute blessing," he said. "I really feel for the kids when basic freedoms we often take for granted, such as walking, running and playing with friends, are unfairly taken away from them." The Arkles Bay resident wants to raise money for Maddy, so he set up a Trade Me auction offering a full day's work around the winner's home. Through the auction and various donations Greg raised $650 and is really happy with the response. "The … Continue reading

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Former East Lancs soldier with Afghanistan brain injury jailed

Posted: Published on August 8th, 2014

Former East Lancs soldier with Afghanistan brain injury jailed 9:17am Friday 8th August 2014 in News By Wendy Barlow, Court reporter AN ex-soldier brain injured after being blown up in Afghanistan has been jailed for a catalogue of drunken violence, after he flouted a chance handed him by a judge. Ashley Clark, 23, a former member of the Duke of Lancaster's infantry, saw two friends die and suffered life-changing injuries as a teenager, when he and his comrades were the victims of a roadside bomb in August 2010. Burnley Crown Court heard how Clark, now a web designer, first began drinking to self-medicate after he was medically discharged from the Army and had found it very difficult to cope with civilian life. Clark had recently started to tackle his problems, but for Judge Andrew Woolman it was too late. The hearing was told how the defendant had had sentence deferred by the judge last December. Clark had lost his temper and racially abused a taxi driver, ranting and swearing and calling him a terrorist, in the early hours of July 25, last year. When police arrived, he struggled with them, bit a female officer on the arm and booted her … Continue reading

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Do you need low T therapy?

Posted: Published on August 8th, 2014

By Dr. Kevin R. Campbell Recently, much has been written about testosterone and male hormone replacement therapies. Symptoms of low testosterone may include fatigue, loss of muscle mass and increased abdominal fat. Other symptoms may include depressed mood, decreased libido and sexual dysfunction. Testosterone replacement therapies have become increasingly popular and many physicians are beginning to offer age management therapies to a wider range of patients. Testosterone is a hormone essential to the development of male growth and masculine characteristics. Currently, testosterone products are FDA-approved only for use in men who lack or have low testosterone levels. Testosterone replacement can be offered in many forms including injections, gels, skin patches and mouth patches. While there are oral testosterone pills available, many experts believe that the oral administration of testosterone may have negative effects on the liver and recommend these other routes of delivery. In the last year, there have been some studies have found that men taking testosterone have more cardiovascular problems, like heart attacks, strokes, and deaths from heart disease. Some physicians also have a lingering concern that testosterone therapy could stimulate the growth of prostate cancer cells. However, when we examine all of the available clinical trial data, … Continue reading

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