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Ghost Organs, Stem Cells, and Frankensteins Transplant Technology

Posted: Published on August 8th, 2014

Ghost Organs, Stem Cells, and Frankensteins Transplant Technology If youre a biotech investor, youre undoubtedly aware of the buzz regarding 3D bioprinting. There have been scores of articles and video presentations in popular outlets heralding the end to transplant organ shortages. Using living cells rather than inanimate construction materials, 3D printing technologies have been used to build models of organs and other tissues. Excitement about the possibility of mass-produced bioprinted transplant organs has fueled a massive inpouring of capital into companies working on this seemingly science fiction technology. Im not writing today to tell you that bioprinting will never succeed in producing viable transplant organs, though the technology has a long way to go with many problems to solve in its path. Ive lived long enough to know that underestimating future scientific progress is a pastime popular among fools and stock shorters. On the contrary, Im writing to tell you an even older biotechnology is much, much nearer the target of lab-grown transplant organs. A few weeks ago, John Mauldin and I visited the Minnesota labs of a company that is pursuing the same goal of transplant organs. During that visit, we held ghost organs, as they are sometimes called, … Continue reading →

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The Aesthetic Medicine Difference – Video

Posted: Published on August 8th, 2014

The Aesthetic Medicine Difference The Aesthetic Medicine Difference? Experience, professionalism, and the widest variety of aesthetic medical treatments all under one roof. More about Aesthet... By: Jerry Darm … Continue reading →

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Growing human GI cells may lead to personalized treatments

Posted: Published on August 8th, 2014

A method of growing human cells from tissue removed from a patient's gastrointestinal (GI) tract eventually may help scientists develop tailor-made therapies for inflammatory bowel disease and other GI conditions. Reporting online recently in the journal Gut, researchers at Washington University School of Medicine in St. Louis said they have made cell lines from individual patients in as little as two weeks. They have created more than 65 such cell lines using tissue from 47 patients who had routine endoscopic screening procedures, such as colonoscopies. A cell line is a population of cells in culture with the same genetic makeup. The scientists said the cell lines can help them understand the underlying problems in the GI tracts of individual patients and be used to test new treatments. "While it has been technically possible to isolate intestinal epithelial stem cells from patients, it has been challenging to use the material in ways that would benefit them on an individual basis," said co-senior investigator Thaddeus S. Stappenbeck, MD, PhD, a professor of pathology and immunology. "This study advances the field in that we have developed new methods that allow for the rapid expansion of intestinal epithelial stem cells in culture. That breaks … Continue reading →

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Dramatic Growth of Grafted Stem Cells in Rat Spinal Cord Injuries

Posted: Published on August 8th, 2014

Contact Information Available for logged-in reporters only Newswise Building upon previous research, scientists at the University of California, San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report that neurons derived from human induced pluripotent stem cells (iPSC) and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons extending virtually the entire length of the animals central nervous system. Writing in the August 7 early online edition of Neuron, lead scientist Paul Lu, PhD, of the UC San Diego Department of Neurosciences and colleagues said the human iPSC-derived axons extended through the white matter of the injury sites, frequently penetrating adjacent gray matter to form synapses with rat neurons. Similarly, rat motor axons pierced the human iPSC grafts to form their own synapses. The iPSCs used were developed from a healthy 86-year-old human male. These findings indicate that intrinsic neuronal mechanisms readily overcome the barriers created by a spinal cord injury to extend many axons over very long distances, and that these capabilities persist even in neurons reprogrammed from very aged human cells, said senior author Mark Tuszynski, MD, PhD, professor of Neurosciences and director of the UC San Diego … Continue reading →

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IVF bombshell for York couples, as NHS backtracks on promise – UPDATED

Posted: Published on August 8th, 2014

IVF bombshell for York couples, as NHS backtracks on promise - UPDATED Updated 10:22am Friday 8th August 2014 in News By Victoria Prest, Political reporter No IVF for York couples COUPLES in York will not be able to get IVF treatment on the NHS this year, after health bosses today backtracked on a decision earlier this summer. The Vale of York CCG's governing body yesterday met and, on a 5-4 vote, delayed offering a single cycle of IVF because it cannot afford the service. Dr Tim Hughes from the CCG said: "It is with a heavy heart that I announce the CCGs Governing Body has voted to temporarily defer the commissioning of IVF services in the Vale of York for 2014-15. The lengthy discussion today highlighted the huge financial pressures the CCG endures whilst meeting its duty to commission safe and effective health and care services." He said the governing body passed a motion "to aspire to commission IVF in the future". York is the only place in the UK not to offer at least one cycle of IVF to couples who cannot conceive naturally, but with an estimated 110 couples wanting IVF, Dr Hughes said the service could cost … Continue reading →

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No IVF for York couples

Posted: Published on August 8th, 2014

COUPLES in York will not be able to get IVF treatment on the NHS this year, after health bosses today backtracked on a decision earlier this summer. The Vale of York CCG's governing body yesterday met and, on a 5-4 vote, delayed offering a single cycle of IVF because it cannot afford the service. Dr Tim Hughes from the CCG said: "It is with a heavy heart that I announce the CCGs Governing Body has voted to temporarily defer the commissioning of IVF services in the Vale of York for 2014-15. The lengthy discussion today highlighted the huge financial pressures the CCG endures whilst meeting its duty to commission safe and effective health and care services." He said the governing body passed a motion "to aspire to commission IVF in the future". York is the only place in the UK not to offer at least one cycle of IVF to couples who cannot conceive naturally, but with an estimated 110 couples wanting IVF, Dr Hughes said the service could cost as much as 2 million a year in York, equating to two hospital wards, 43 full time nurses, nearly 300 hip replacement operations or 21,500 trips to A&E. York IVF … Continue reading →

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Bigfoot and yeti, as elusive as ever

Posted: Published on August 8th, 2014

Legends of mysterious part-human creatures have circulated for centuries, and those stories persist today in cultures around the world, from Yeti in the Himalayas to the Almas, or wild man, in Central Asia to Sasquatch, aka Bigfoot, in North America. Now a research team has performed the first rigorous genetic analysis of three dozen hair samples that their collectors claimed came from such undiscovered, living humanoids. Like everyone else, I was curious to know what was at the bottom of all of the rumors and myths, said Bryan Sykes, a professor of human genetics at the University of Oxford, who led the study. The samples, it turned out, belonged to a range of creatures: raccoons, sheep, bears, dogs, humans and more. Bigfoot, however, was not one of them. Sykes and his colleagues acquired 57 hair samples from museums and collectors in the Himalayas, Russia, the United States and Indonesia. After excluding two non-hair samples, the team selected 36 of the remaining ones for analysis. They thoroughly cleaned the hairs using forensic techniques and then sequenced mitochondrial DNA recovered from the hair shafts. Thirty of the samples yielded genetic material, which they compared with listings in a genetic database of known … Continue reading →

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Genetics of Autism Spectrum Disorders, Dr. Abha Gupta – Video

Posted: Published on August 8th, 2014

Genetics of Autism Spectrum Disorders, Dr. Abha Gupta Dr. Gupta discusses the evidence for a genetic etiology in autism and the results of various genetics studies of autism. She also reviews recommendations for clinical genetics testing and future... By: YaleUniversity … Continue reading →

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Genetically modified crops: Ignoring genetic engineering at our own peril

Posted: Published on August 8th, 2014

Some British newspapers have been reporting the imminent harvest of a variety of nutrition-enriched genetically modified (GM) crop in the UK. It is a crop called camelina, also called false flax, a plant that usually grows in the Mediterranean. An institute called Rothamsted Research has tweaked the plant's genes and produced a variety that is full of omega-3 fatty acids, normally found only in oily fish. Consumption of omega-3 fatty acids is supposed to be beneficial in a number of ways, and so this crop would provide the first real chance for vegetarians to get the vital nutrient through their normal diet. This would be great news for many people, but what is equally important is the fact that GM crops are set to finally break the resistance in Europe. Despite considerable opposition from various pressure groups, GM crops are slowly advancing in Europe, with regulators relenting in several countries. Two months ago, almost all the environment ministers in Europe - only two countries resisted - decided to let individual countries follow their own course: whether to allow or not allow the cultivation of GM crops. This will let the pro-GM countries go ahead with their plans, which will probably … Continue reading →

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Solid-State Chemistry

Posted: Published on August 8th, 2014

Contact Information Available for logged-in reporters only Newswise WASHINGTON D.C., Aug. 7, 2014 Nature writ large is filled with examples of transformative chemical reactions that take place in the solid state -- minerals found deep underground or on the surface of the earth that undergo chemical reactions over time when they are subjected to the right mix of environmental conditions. The same cannot always be said for synthetic chemistry at the industrial scale. Factories that make pharmaceutical drugs and ore processing plants where precious metals are extracted from mined minerals tend to rely not on solids but solution chemistry -- mixing salts or rocks with large volumes of often highly corrosive or toxic liquids to achieve chemical reactions and extract useful products. Those solvents, besides being expensive, often corrosive, and sometimes toxic to the environment, may be dangerously volatile -- even explosive. Now a team of researchers led by Tomislav Frii, a professor at McGill University, is developing new approaches to chemical synthesis and mineral processing based on solid-state chemistry -- and inspired by examples from nature. At the 23rd Congress and General Assembly of the International Union of Crystallography, held August 5-12, 2014 in Montreal, Frii will describe some … Continue reading →

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