Nicholas C. Johnson, PharmD Candidate, Class of 2021 and Adebola Akunna, PharmD, BCPS As research has ensued, more harmful compounds have been found present in e-cigarette aerosol, similar to the well-established negative health outcomes associated with traditional tobacco cigarettes.2,3 Although it has been established that e-cigarette vapors, by and large, contain fewer total compounds than traditional tobacco cigarettes, they often still contain numerous toxic substances, albeit at lower concentrations.4 Atherosclerosis and Nicotine Nicotine, the primary shared compound between e-cigarette and traditional tobacco, has been a well-established catalyst for the development of atherosclerotic cardiovascular disease. Nicotine has been shown to induce the release of catecholamines and cortisol, cause hemodynamic changes (increased blood pressure, heart rate, and vasoconstriction), and cause adverse changes in lipid profiles (increased saturated fat content, decreased unsaturated fat content, and increased total cholesterol).5 Additionally, e-cigarette users have been found to have significantly decreased vascular elasticity, which may lead to heart disease and stroke, along with similar inflammatory infiltrate of the vasculature seen in cigarette smokers that lead to atherosclerosis over time.5 Other findings that correlate to nicotine exposure, either first- or second-hand, include aortic stiffness, insulin resistance, inhibition of apoptosis, and promotion of angiogenesisall of which may accelerate atherosclerotic (and malignancy) progression Continue reading →

Four years ago today, on the Monday after Tom Brady's 5th Super Bowl victory, I found myself in a very unusual situation, but, also in very good hands. (You can view the story from 2017) The Patriots had just beaten the Falcons in that classic Tom Brady come from behind victory in Super Bowl LI. I had watched the game with my family from a hospital bed at University of Iowa Hospitals and Clinics in Iowa City. Continue reading →

Sarah Swift discusses why women may be worse off when it comes to diagnosing and treating cardiovascular pathologies and emphasises the importance of changing perspectives Heart disease is the leading cause of death for women worldwide but alarmingly, according to a briefing released by the British Heart Foundation (BHF), they are 50% more likely than men to be misdiagnosed. Continue reading →

RARITAN, N.J., Feb. 8, 2021 /PRNewswire/ -- The Janssen Pharmaceutical Companies of Johnson & Johnson announced today resultsfrom the randomized, double-blind, placebo-controlled Phase 3 ACIS study, which met the primary endpoint of radiographic progression-free survival (rPFS) with a 31 percent reduction in the risk of radiographic progression or death in patients with chemotherapy-nave metastatic castration-resistant prostate cancer (mCRPC) receiving androgen deprivation therapy (ADT) Continue reading →

COVID-19 can affect the global economy in three main ways: by directly affecting production and demand, by creating supply chain and market disruption, and by its financial impact on firms and financial markets. Myocardial Infarction Treatment Market size has covered and analyzed the potential of Worldwide market Industry and provides statistics and information on market dynamics, market analysis, growth factors, key challenges, major drivers & restraints, opportunities and forecast. This report presents a comprehensive overview, market shares, and growth opportunities of market 2028 by product type, application, key manufacturers and key regions and countries. Continue reading →

Troponin Market The Troponin Market projections and Trends for 2020 to 2029: Regal intelligences most recent report provides meaningful insights on the impact of COVID-19 on the Troponin market how key competitors of the industry are positioning their businesses in the unequal times of coronavirus epidemic which has disrupted the business activities and has seriously affected the countries economies. Flowcharts, graphs and trends are studied in detail to analyze the business environment in order to evaluate relevant information and apply solutions to gain a competitive advantage in the industry of Troponin markets. Furthermore, the Troponin market research report analyzes the dynamic market trends of the industry for evaluating significant CAGR during the forecast period. Continue reading →