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Effect of microenvironment modulation on stem cell therapy for spinal cord injury pain

Posted: Published on August 2nd, 2014

PUBLIC RELEASE DATE: 31-Jul-2014 Contact: Meng Zhao eic@nrren.org 86-138-049-98773 Neural Regeneration Research Spinal cord injury (SCI) currently ranks second after mental retardation among neurological disorders in terms of cost to society. Pain is a debilitating consequence of SCI related to the nature of the lesion, neurological structures damaged, and secondary pathophysiological changes of surviving tissues1. Approximately two-thirds of persons who have sustained SCI experience clinically significant pain after injury, of whom one-third have severe pain2, 3. Post-SCI pain can increase with time and is often refractory to conventional treatment approaches4. Over the past decade, clinical studies have shown that post-SCI pain interferes with rehabilitation, daily activities, and quality of life and may substantially influence mood, leading to depression and even suicide4-7.Chronic neuropathic pain following SCI is divided into three types: at-level pain (pain within the body segments innervated by spinal cord segments at the level of the injury), below-level pain (pain within body segments caudal to the level at which the spinal cord was injured), and above-level pain (pain within body segments rostral to the level at which the spinal cord was injured)8. The mechanisms underlying SCI-induced chronic neuropathic pain are not well understood. Aberrant central sprouting of nociceptive fibers … Continue reading →

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Fertility Centre Delhi | IVF Delhi | IVF Specialist | female infertility | IVF Treatment Delhi – Video

Posted: Published on August 2nd, 2014

Fertility Centre Delhi | IVF Delhi | IVF Specialist | female infertility | IVF Treatment Delhi International Fertility Centre provides best Infertility treatment in Delhi. You can consult regarding Infertility treatment at any time with our expert doct... By: IVF India … Continue reading →

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Good samaritan donates 500 to widow denied IVF treatment with dead husband’s sperm

Posted: Published on August 2nd, 2014

Donna Turner is one step closer to fulfilling her late husband's dying wish[INS ] New bride, Donna Turner, 32, was left distraught after her local NHS refused to carry out the 3,500 IVF treatment to fulfil her late husband Paul's dying wish because it would make her a single parent. Mr Turner died from bowel cancer in January 2013, aged 39, just eight months after the couple married. Now good samaritan William Brady has written a 500 cheque to help Mrs Turner get one step closer to raising the cash to have it done privately. The father-of-two from Addlestone in Surrey, said: "I'm just a sincere well-wisher. "I love my kids so much and I think this lady should have a chance of having that happiness. If she can't get it through the National Health I would hope she can get it through private means." Although prompted by his disgust at the NHS's decision Mr Brady said he recently had treatment on the NHS and was keen to stress it was vastly different to Mrs Turner's. "They were absolutely brilliant to me, I can't speak highly enough of the staff. "But I am disgusted at some of the cases where … Continue reading →

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Midsummer Nights’ Science: Progress in psychiatric genetics – Video

Posted: Published on August 2nd, 2014

Midsummer Nights' Science: Progress in psychiatric genetics Copyright Broad Institute, 2013. All rights reserved. To find genes that underlie traits or diseases, scientists often conduct genome-wide association studies (GWAS). GWAS scan the entire... By: broadinstitute … Continue reading →

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Scientists oppose experiments on GM crops

Posted: Published on August 2nd, 2014

A group of scientists Friday wrote to Prime Minister Narendra Modi protesting the Genetic Engineering Appraisal Committee's decision to carry on experiments on GM crops as these adversely impact the environment. "It is shocking that GEAC took this decision in its first meeting after your government took charge. It is unfortunate the committee continues to follow the unscientific approach towards environmental release of GMOs (Genetically Modified Organisms) when there is growing scientific evidence on the adverse impact of GMOs on human health and environment," said the letter. The GEAC under the environment, forests and climate change ministry recently approved numerous experiments on GM crops, including many GM food crops. The letter was written by P.M. Bhargava, Padma Bhushan awardee and former member of National Knowledge Commission; Minoo Parabia, retired professor of Bio-Sciences at the Veer Narmad South Gujarat University; V.S. Vijayan, former chairman of Kerala State Biodiversity Board; Dinesh Abrol, visiting professor at the Centre for Studies in Science Policy and Tushar Chakraborty, senior scientist at the Indian Institute of Chemical Biology, Kolkata. They added in the letter that opposition to open release of GMOs originated in scientific circles and continues to be fuelled by ever-growing scientific evidence of its … Continue reading →

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X-men gene therapy session (ASMR) – Video

Posted: Published on August 2nd, 2014

X-men gene therapy session (ASMR) My first attempt at an ASMR video after lurking for so long. A huge thanks to Heatherfeather for making her amazing videos and answering all of my messages. You are the very first test subject... By: Legendoflink … Continue reading →

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Treating Disease in Babies Before Birth: The Third Option – Anna David at TEDxUCLWomen – Video

Posted: Published on August 2nd, 2014

Treating Disease in Babies Before Birth: The Third Option - Anna David at TEDxUCLWomen Is there a way to treat disease in babies before birth? In this informative talk, Anna David, Associate Professor at the UCL Institute for Women's Health, discusses how foetal gene therapy... By: TEDx Talks … Continue reading →

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Christian ethicists concerned over ‘three parent baby’ IVF plan

Posted: Published on August 2nd, 2014

Ben Birchall/PA Wire Christian ethicists have joined scientists in expressing concern about the latest Government steps towards creating what have been dubbed "three-parent babies". The Church of England is among those calling for more research. The Government last week published its response to a 12-week Human Fertilisation and Embryology Authority (HFEA) consultation on draft regulations to permit the use of new techniques to prevent transmission of seriousmitochondrial disease from mother to child. Some oppose the proposed IVF technique, "mitochondrial replacement therapy", because they believe it is a form of genetic modification and creates children with, in effect, three parents. The Government response emphasises that no nuclear DNA, which provides physical and other traits that children inherit from their parents, would be contributed from the donated female egg or embryo. The Government has consistently rejected claims that the techniquesconstitute genetic modification. Critics are protesting in particular against the Government's working definition in the document of genetic modification to mean the modification only of nuclear DNA in the chromosome meaning that mitochondrial donation techniques are not being counted as actual genetic modification. It is estimated that one in 6,500 children are born each year with serious mitochondrial DNA disorder which can have … Continue reading →

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Spurrier: Chemistry apparent on the field

Posted: Published on August 2nd, 2014

FILE - In this Sept. 28, 2013 file photo, South Carolina head coach Steve Spurrier calls for a timeout against Central Florida during the second half of an NCAA college football game in Orlando, Fla. Spurrier wasn't sure he'd hang around 10 seasons at South Carolina when he took the job. Now he isn't ready to leave. (AP Photo/John Raoux, File) COLUMBIA - Lorenzo Ward had walked barely 10 steps off the football field after South Carolina's first preseason practice, but he'd seen enough to fuel already high expectations. "I think there's a little something different about this team," the Gamecocks defensive coordinator said. Under the lights, Ward was impressed with what he witnessed Friday night. He was heading toward his office, ready to study the film and further evaluate the practice. But what had Ward smiling was something that can't be seen on film. "I just think there's something special about them," Ward continued. "I think the way that they're about business. There's no big-name players on this team, and so they're like family and they play as a team. I think it's something special when you do that." Less than four weeks from their first game, there are … Continue reading →

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U.S. Basketball Team Bonding In Vegas

Posted: Published on August 2nd, 2014

Sports Fan Insider Keep up with your favorite teams and athletes with daily updates. LAS VEGAS (AP) - Brotherhood, chemistry and camaraderie. Those three words have been used repeatedly during the U.S. basketball teams first four days of practice. Its those things that will help bring together the final 12-man roster for the squad that will compete in the FIBA World Championships in Spain. A lot of guys make it to the NBA and thats a fraternity, Golden State guard Stephen Curry said after practice Thursday at UNLVs Mendenhall Center. But this is a selective fraternity guys that have been able to wear a USA jersey and play competitive international basketball. Brotherhood is a good term. Curry, who won a gold medal with the team that went 9-0 in the 2010 World Championships, will likely have his passport stamped, along with fellow returners Kevin Durant and Derrick Rose. Add in James Harden and Anthony Davis, who both joined the team that won the 2012 Olympics, and coach Mike Krzyzewski has the core he needs to build around. Krzyzewski has said all week that this years team is not about choosing from a group of individual NBA All-Stars, but rather finding … Continue reading →

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