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Shelton firms products in the pipeline could end diseases

Posted: Published on July 30th, 2014

A company specializing in the emerging field of nanomedicine has opened in Shelton, offering the possibility that major healthcare advances could be developed in the city. U.S. Rep. Jim Himes cuts the ribbon at the new NanoViricides facility in Shelton while joined by company officials, including President and Chairman Anil R. Diwan, Interim Chief Financial Officer Meeta Vyas and Chief Executive Officer Eugene Seymour. The products being produced here could very well end diseases such as influenza and dengue fever, U.S. Rep. Jim Himes said at this weeks opening of the NanoViricides Inc. facility on Controls Drive. This is truly a game changer for humankind, Himes said. He predicted the companys president and chairman, Anil R. Diwan, could even win the Nobel Prize in medicine if products now in development at NanoViricides succeed. Diwan said the firm has six medicines in the pipeline that would treat the flu, dengue, HIV, herpes (cold sores) and eye viruses. With money raised from investors, NanoViricides has bought the 18,000-square-foot building at 1 Controls Drive, near Long Hill Cross Road. The company is now moving its facilities and employees there from West Haven. The Shelton site will include manufacturing areas, labs, research-and-development space and … Continue reading →

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How does microRNA-124 promote the neuronal differentiation of BMSCs?

Posted: Published on July 29th, 2014

PUBLIC RELEASE DATE: 28-Jul-2014 Contact: Meng Zhao eic@nrren.org 86-138-049-98773 Neural Regeneration Research MicroRNAs (miRNAs) play an important regulatory role in the self-renewal and differentiation of stem cells. Dr. Defeng Zou and co-workers from the First Affiliated Hospital of China Medical University, China focuses on the effect of miRNA overexpression on the differentiation of bone marrow-derived mesenchymal stem cells into neurons. In the study released on the Neural Regeneration Research (Vol. 9, No. 12, 2014), researchers used GeneChip technology to analyze the expression of miRNAs in bone marrow-derived mesenchymal stem cells, neural stem cells and neurons. They constructed a lentiviral vector overexpressing miR-124 and transfected it into bone marrow-derived mesenchymal stem cells. Intracellular expression levels of the neuronal early markers -III tubulin and microtubule-associated protein-2 were significantly increased, and apoptosis was reduced in transfected cells. After miR-124-transfected bone marrow-derived mesenchymal stem cells were transplanted into the injured rat spinal cord, a large number of cells positive for the neuronal marker neurofilament-200 were observed in the transplanted region. The Basso-Beattie-Bresnahan locomotion scores showed that the motor function of the hind limb of rats with spinal cord injury was substantially improved. These results suggest that miR-124 plays an important role in the differentiation … Continue reading →

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Osiris Stem Cells To Compliment Mannkind's Afrezza In Disrupting Diabetes Market

Posted: Published on July 29th, 2014

Published at Retail Investor 360: Monday, 28 July 2014 20:02 by Doctor Hung V. Tran, MD, MS Disclosure: I am long on MNKD. Due to its capacity to self-renew and give rise to cells of various lineage, mesenchymal stem cells (MSCs) have generated a great amount of enthusiasm over the past decade as a novel therapeutic paradigm for a variety of diseases. The leading, integrated stem cell company Osiris Therapeutics (NASDAQ:OSIR) thus indeed has captured and gained a significant impact in this unique market since infancy with its capabilities in groundbreaking research, development, manufacturing, marketing and distribution of stem cell products to treat unmet medical conditions in orthopedic, sport medicine and specifically wound care markets. Source: Stem Cell Giving the diabetes mellitus market is growing at a rapid rate globally; roughly 25 million or 8.3% of the U.S. population suffer from this condition. With its FDA approved super rapid acting insulin, Afrezza, that could mimic the actions of healthy pancreas, Mannkind Corporation (NASDAQ: MNKD) is already positioned it self to become the new leader in this huge insulin market. Diabetic complications such as diabetic foot ulceration, infection, and gangrene are significant complications and the leading causes of hospitalization in patients … Continue reading →

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Obese women as likely to give birth following IVF as those of normal weight

Posted: Published on July 29th, 2014

As the nations assistedreproduction experts weigh whether obese women should be refused fertility treatments, a new study finds obese women are as likely to get pregnant and have a baby following IVF as women of normal weight. Dalhousie University researchers who looked at 752 women who underwent IVF, or invitro-fertilization, at a private fertility clinic in Halifax found obese women do not require higher doses of fertility drugs. There were also no significant differences in the odds of achieving a pregnancy or live birth between normal weight, overweight and obese women. Growing numbers of obese women are seeking treatment for infertility. But some IVF clinics in Canada are imposing strict BMI cutoffs, a controversial practice that is expected to resurface at the Canadian Fertility and Andrology Societys annual meeting in September. The British Fertility Society recommended in 2006 that women with a BMI, or body mass index, greater than 35 be denied IVF. Some clinics in New Zealand have a BMI cutoff of 32. But the Halifax team says their findings suggest that there may be insufficient justification for placing these arbitrary BMI restrictions on IVF treatment access. Other fertility experts said the study was too small to draw conclusions, … Continue reading →

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Obese women no less likely to give birth after IVF, study suggests

Posted: Published on July 29th, 2014

As the nation's assisted reproduction experts weigh whether obese women should be refused fertility treatments, a new study finds obese women are as likely to get pregnant and have a baby following IVF as women of normal weight. Dalhousie University researchers who looked at 752 women who underwent IVF, or invitro-fertilization, at a private fertility clinic in Halifax found obese women do not require higher doses of fertility drugs. There were also no significant differences in the odds of achieving a pregnancy or live birth between normal weight, overweight and obese women. Growing numbers of obese women are seeking treatment for infertility. But some IVF clinics in Canada are imposing strict BMI cutoffs, a controversial practice that is expected to resurface at the Canadian Fertility and Andrology Society's annual meeting in September. The British Fertility Society recommended in 2006 that women with a BMI, or body mass index, greater than 35 be denied IVF. Some clinics in New Zealand have a BMI cutoff of 32. But the Halifax team says their findings suggest "that there may be insufficient justification for placing these arbitrary BMI restrictions on IVF treatment access." Other fertility experts said the study was too small to draw … Continue reading →

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University of Maryland Schools of Dentistry and Medicine receive NIH grant

Posted: Published on July 29th, 2014

PUBLIC RELEASE DATE: 29-Jul-2014 Contact: Christopher Hardwick chardwick@som.umaryland.edu 410-706-5260 University of Maryland School of Medicine The University of Maryland Schools of Dentistry (UM SOD) and Medicine (UM SOM) jointly announced today that they have received a five-year $10.7 million grant award from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health to study the causes, prevention and treatment of sexually-transmitted diseases (STDs). The grant, which renews a previous $12 million five-year NIAID-funded research program, represents a new direction for the research by studying chlamydial and gonorrheal diseases as the outcome of complex interactions between the host genetics, the urogenital polymicrobial microbiome, and the pathogen's unique genetics. By applying modern "omics" technology, the study aims at identifying novel molecular "biomarkers" of susceptibility to sexually transmitted infections (STIs), ensuing disease severity, and conversely protection from STIs and STDs. Biomarkers can be measured in the body (or its products) as a means to predict and potentially influence pathways related to disease. They may reveal mechanisms of infection or disease that can be exploited as therapeutic or diagnostic targets. The long-term goal of the research is to develop strategies and the means to reduce the incidence of STIs … Continue reading →

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Ramin Pashaie on Optogenetics – (optics + molecular genetics) – Video

Posted: Published on July 29th, 2014

Ramin Pashaie on Optogenetics - (optics + molecular genetics) Could we possibly help blind people to see real life the way they see dreams? Ramin Pashaie thinks we can! By: UWM CEAS … Continue reading →

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PCMag Live 07/25/14: Google X Genetics & Sharknado 2 Light Show – Video

Posted: Published on July 29th, 2014

PCMag Live 07/25/14: Google X Genetics Sharknado 2 Light Show Samara Lynn Max Eddy chat about the day's top tech news, including a WSJ report that Google's Baseline Study project will collect anonymous genetic and mol... By: PCMag … Continue reading →

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Lets Play The Sims 3 Perfect Genetics-100 Baby Challenge Part 1 – Video

Posted: Published on July 29th, 2014

Lets Play The Sims 3 Perfect Genetics-100 Baby Challenge Part 1 Watch the CAS and finding a house for our founder. -- http://www.twitch.tv/gbabychallenger/c/4750293 utm_campaign=archive_export utm_source=gbabychallenger utm_medium=youtube. By: GBabyChallenger … Continue reading →

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Freezing Zero cap 13 28ava Generacion de West Genetics III – Video

Posted: Published on July 29th, 2014

Freezing Zero cap 13 28ava Generacion de West Genetics III Agradecimientos por la traduccion Santos-Scans visita http://santos-scans.me/ MUsica: X-Ray Dog - Night Hounds [Modern Drama] On Your Knees (No Guitar Melody) Learning To Fly Audiomachine-P... By: XXXTestamentoXXX … Continue reading →

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