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Stroke treatment enhanced by magnetised nanoparticles

Posted: Published on July 21st, 2014

22 July 2014 University of Georgia researchers and their collaborators have developed a new technique to enhance stroke treatment using magnetically controlled nanomotors to transport a clot-busting drug to blockages in blood vessels. The only drug currently approved for the treatment of acute stroke - recombinant tissue plasminogen activator (t-PA) - is administered intravenously to patients after the first symptoms of ischemic stroke appear. The protein in the drug dissolves blood clots that cause strokes and other cardiovascular problems, such as pulmonary embolisms and heart attacks. Our technology uses magnetic nanorods that, when injected into the bloodstream and activated with rotating magnets, act like stirring bars to drive t-PA to the site of the clot, said Yiping Zhao, co-author of a paper describing the results in ACS Nano and professor of physics in UGAs Franklin College of Arts and Sciences. Our preliminary results show that the breakdown of clots can be enhanced up to twofold compared to treatment with t-PA alone. By collaborating with their medical partners, the researchers tested their approach in mice that mimic blood clots in humans. Once a clot was formed, they injected a mixture of t-PA and a small number of magnetic nanorods measuring 300nm … Continue reading →

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Stroke Rates Have Dropped 40% for People 65+

Posted: Published on July 21st, 2014

A new analysis of data from 1988-2008 by researchers at the University of California San Francisco School of Medicine has revealed a 40% decrease in the incidence of stroke in Medicare patients 65 years of age and older. The decline is greater than anticipated considering this population's risk factors for stroke. Not only that, but the drop applies to both ischemic and hemorrhagic strokes. The team also found that deaths resulting from stroke declined during the same period. The findings are published in the July 2014 issue of The American Journal of Medicine. A release from the publisher notes that stroke is the fourth leading cause of mortality in the United States, with approximately 795,000 strokes occurring each year. Beyond the impact on patients, treatment and after care place high demands on doctors and health care facilities. With an aging population reaching Medicare age, deconstructing and studying stroke statistics are important for understanding the causes underlying this downward trend, benefiting both patients and providers. The release quotes lead investigator Margaret C. Fang, MD, MPH as saying, "Shedding light on trends in the burden of stroke among Medicare beneficiaries may provide important information for policy purposes, including describing the past and … Continue reading →

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Soccer Superstars Fractured Vertebra Healing Well

Posted: Published on July 21st, 2014

Los Angeles, CA (PRWEB) July 21, 2014 According to a recent article, Brazilian star player Neymars fractured vertebra which took him out of the semifinal World Cup match is healing well. Dr. Todd Gravori of ProMed SPINE treats many back injuries, including fractured vertebra resulting from trauma to the spine. He performs back surgery in Los Angeles with an extremely high success and patient satisfaction rate. He commented on Neymars injuries, and how lucky the soccer player is to be healing so fast. Fractured vertebrae can be debilitating, said Dr. Gravori. In some cases a piece of bone may break off and enter the spinal canal, or the spinal cord could be compressed by slippage. Neymar is fortunate that his injury was mild enough to require only conservative treatment. Neymars fracture occurred in the lumbar region of the spine, and he had to be carried off the field in intense pain. However, the fracture does not require surgery, and doctors believe he will heal fully with just a back brace. For small fractures that have not caused neurologic injury, an external back brace is enough to immobilize the spine and allow the fracture to heal. Whenever a person suffers injury … Continue reading →

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Treatment aims to limit use of drugs: Hyperbaric oxygen offered to returning veterans with traumatic injuries

Posted: Published on July 21st, 2014

BULLHEAD CITY There is a movement under way to treat returning military veterans with traumatic brain injury (TBI) and post-traumatic stress injury (PTSI) with Hyperbaric Oxygen Therapy (HBOT) instead of drugs. Were losing a soldier an hour to suicide, said Janet Franco, who hosts a Las Vegas-based radio program dedicated to helping veterans with those afflictions. Whats happening when they get back (from active duty) is the high amounts of pharmaceutical drugs that are administered to our soldiers. The side effects are causing more damage than good when it comes to depression and suicidal thoughts, Franco said. She had a son with a head injury and he tried two or three times to kill himself over the years, so Im very familiar with what these families go through, she said. To say that we are in a state of emergency is an understatement, Franco said. The Mayo Clinic website, mayoclinic.org, describes the process known as HBOT: Your bodys tissues need an adequate supply of oxygen to function. When tissue is injured, it requires even more oxygen to survive. Hyperbaric oxygen therapy increases the amount of oxygen your blood can carry. An increase in blood oxygen temporarily restores normal levels of … Continue reading →

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Tributes paid on anniversary of St Kilda murder

Posted: Published on July 21st, 2014

Paying respects: Mourners remember Tracy Connelly. Photo: Joe Armao One year after sex worker Tracy Connelly was murdered, many have returned to the place where she died to commemorate her. About 100 people stood holding candles outside sex worker support group St Kilda Gatehouse's headquarters on Monday night. Ms Connelly's partner, Tony Melissovas, found her body in the van where they lived, parked on Greeves Street on July 21, 2013. Mr Melissovas has been cleared as a suspect because he was receiving treatment for a hand injury on the night of her death. He was also at the event on Monday, which doubled as a tribute to other women who had been victims of violence. Tracy Connelly. Police believe that Tracy was killed by one of her clients, and that robbery may have been a motive. Advertisement They have yet to charge anyone with her murder, but are looking through thousands of number plates of cars in the area which Mr Melissovas recorded. Detective Senior Sergeant Stuart Bailey, who was at the memorial on Monday, said police had spoken to several people there who gave them information about new people they could speak to in their investigation. He urged the … Continue reading →

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Hormone Replacement Therapy – Alegent Creighton Clinic – Video

Posted: Published on July 21st, 2014

Hormone Replacement Therapy - Alegent Creighton Clinic As a woman approaches menopause, the production of estrogen and progesterone fluctuates and then decreases significantly. Symptoms such as hot flashes often ... By: Alegent Creighton Health … Continue reading →

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Motoneuron-like cell transplantation and GDNF delivery for repair of SCI

Posted: Published on July 21st, 2014

PUBLIC RELEASE DATE: 18-Jul-2014 Contact: Meng Zhao eic@nrren.org 86-138-049-98773 Neural Regeneration Research Adipose-derived stem cells-transdifferentiated motoneurons after transplantation can integrate in the host cord. However, cell survival has been restricted by a lack of ideal environment for nerve cell growth. Taki Tiraihi, Shefa Neuroscience Research Center at Khatam Al-Anbia Hospital, Iran developed rat models of spinal cord injury (SCI) and injected adipose-derived stem cells-transdifferentiated motoneurons into the epicenter, rostral and caudal regions of the impact site and simultaneously transplanted glial cell line-derived neurotrophic factor (GDNF)-gelfoam complex into the myelin sheath. Motoneurons-like cell transplantation combined with GDNF delivery reduced cavity formations and increased cell density in the transplantation site. The combined therapy exhibited superior promoting effects on recovery of motor function to transplantation of GDNF, adipose-derived stem cells or motoneurons alone. These findings suggest that motoneuron-like cell transplantation combined with GDNF delivery holds a great promise for repair of spinal cord injury. Related results were published in Neural Regeneration Research (Vol. 9, No. 10, 2014). ### Article: "Intraspinal transplantation of motoneuron-like cell combined with delivery of polymer-based glial cell line-derived neurotrophic factor for repair of spinal cord contusion injury" by Alireza Abdanipour, Taki Tiraihi, Taher Taheri (Shefa Neuroscience Research Center at … Continue reading →

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Stem cells aid muscle repair and strengthening after resistance exercise

Posted: Published on July 21st, 2014

PUBLIC RELEASE DATE: 21-Jul-2014 Contact: Diana Yates diya@illinois.edu 217-333-5802 University of Illinois at Urbana-Champaign CHAMPAIGN, Ill. A new study in mice reveals that mesenchymal (mezz-EN-chem-uhl) stem cells (MSCs) help rejuvenate skeletal muscle after resistance exercise. By injecting MSCs into mouse leg muscles prior to several bouts of eccentric exercise (similar to the lengthening contractions performed during resistance training in humans that result in mild muscle damage), researchers were able to increase the rate of repair and enhance the growth and strength of those muscles in the exercising mice. The findings, described in the journal Medicine and Science in Sports and Exercise, may one day lead to new interventions to combat age-related declines in muscle structure and function, said University of Illinois kinesiology and community health professor Marni Boppart, who led the research. "We have an interest in understanding how muscle responds to exercise, and which cellular components contribute to the increase in repair and growth with exercise," she said. "But the primary goal of our lab really is to have some understanding of how we can rejuvenate the aged muscle to prevent the physical disability that occurs with age, and to increase quality of life in general as well." MSCs … Continue reading →

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New IVF treatment offers safer, less complicated pregnancies to women

Posted: Published on July 21st, 2014

Within in-vitro fertilization (IVF), one of the most common complications women have is known as ovarian hyperstimulation syndrome (OHSS). This may lead to kidney failure in about five percent of patients who go through IVF, and can often times prove fatal on the fetus. Now, scientists have revealed a new type of IVF that is more natural and less hazardous, which could possibly change the face of IVF in the future. OHSS can cause ovarian swelling, which can affect any woman without regard to her health. This can lead to infertalization and life-threatening reactions. The new treatment uses the hormone kisspeptin, which is more natural than the traditional methods, reports The Independent. The trials began last January at Imperial College London, and since then there have been a total of 12 healthy babies from the 53 original volunteers. According to Science 2.0, kisspeptin is a naturally occurring hormone within the body, and it is much easier to use kisspeptin to stimulate reproductive hormones. "Our study has shown that kisspeptin can be used as a physiological trigger for egg maturation in IVF therapy," said Professor Waljit Dhillo, who led the study. "It's been a joy to see 12 healthy babies born … Continue reading →

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Growing numbers of British parents going to US for IVF to choose sex of child

Posted: Published on July 21st, 2014

Selecting baby's sex before birth is currently banned in the UK Many believe nature should decide and fear a populationimbalance But US doctor says couples have the right to choose and more are He sees 10 patients a month fly from UK for the treatment in the US 80 per cent of parents opt for a baby girl and 20 per cent want a boy By Richard Spillett Published: 23:35 EST, 20 July 2014 | Updated: 03:04 EST, 21 July 2014 54 shares 35 View comments Controversial: Dr Daniel Potter runs a clinic in the US which allows couples to choose the sex of their baby in treatment costing 7,600 Increasing numbers of British parents are flying to the US for a controversial IVF treatment which allows them choose the sex of their baby, a leading expert has revealed. Dr Daniel Potter, who runs the largest fertility clinic on the West Coast of America, has delivered 750 babies to UK mothers since he started in 1997. Visits from UK women have risen by 20 per cent year on year to the IVF specialist, which allows them to choose the sex of their baby using a process currently banned in Britain. … Continue reading →

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