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Important Clue To Cancer Provided By DNA Origami Nano-tool

Posted: Published on July 9th, 2014

July 8, 2014 Image Caption: DNA-origami. Credit: Bjrn Hgberg Karolinska Institutet Researchers at Karolinska Institutet in Sweden have headed a study that has provided new knowledge about the EphA2 receptor, which is significant in several forms of cancer. This is important knowledge in itself but just as important is how this study, which is published in the highly respected journal Nature Methods today, was conducted. The researchers used the method of DNA origami, in which a DNA molecule is shaped into a nanostructure, and used these structures to test theories about cell signalling. It was previously known that the EphA2 receptor played a part in several forms of cancer, such as breast cancer. The ligand, i.e., the protein that communicates with the receptor, is known as an ephrin molecule. Researchers have had a hypothesis that the distance between different ligands in this case the distance between ephrin molecules affects the level of activity in the communicating receptor of the adjacent cells. The Swedish researchers set out to test this hypothesis. They used DNA building blocks to form a stable rod. This has then been used as a very accurate measure of the distance between molecules. We use DNA as the … Continue reading

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DNA from aborted fetus led to arrest in assault on teen

Posted: Published on July 9th, 2014

KISSIMMEE DNA from an aborted fetus led to the arrest last weekend of a suspect charged with having sex with a 14-year-old girl he met on Facebook, according to police records. Kevon Butler, 23, was charged over the July Fourth holiday weekend with seducing an impregnating the teen last fall after renting a room for the night at a motel on Vine Street, records state. The girl's parents found about the relationship when Butler's girlfriend called and told them about the underage affair with the convicted cocaine dealer. The teenager later told police she might have had unprotected sex with him, records state. In early November less than a month after she met Butler the teen's father notified police that she was pregnant and that the pregnancy would be terminated within the week at an out-of-town clinic. A detective and a crime scene technician went to the clinic and collected a DNA specimen after the procedure, records show. The specimen was stored in a police evidence freezer at the Kissimmee Police Department as detectives continued to investigate the case. In April, police collected two DNA specimens from Butler and sent all of the specimens to the Florida Department of Law … Continue reading

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DNA origami nano-tool provides important clue to cancer

Posted: Published on July 9th, 2014

Researchers at Karolinska Institutet in Sweden have headed a study that provides new knowledge about the EphA2 receptor, which is significant in several forms of cancer. This is important knowledge in itself -- but just as important is how this study, which is published in the highly respected journal Nature Methods, was conducted. The researchers used the method of DNA origami, in which a DNA molecule is shaped into a nanostructure, and used these structures to test theories about cell signalling. It was previously known that the EphA2 receptor played a part in several forms of cancer, such as breast cancer. The ligand, i.e., the protein that communicates with the receptor, is known as an ephrin molecule. Researchers have had a hypothesis that the distance between different ligands -- in this case the distance between ephrin molecules -- affects the level of activity in the communicating receptor of the adjacent cells. The Swedish researchers set out to test this hypothesis. They used DNA building blocks to form a stable rod. This has then been used as a very accurate measure of the distance between molecules. "We use DNA as the construction material for a tool that we can experiment with," … Continue reading

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Building Lab Directions- 1381 Chemistry Building – Video

Posted: Published on July 9th, 2014

Building Lab Directions- 1381 Chemistry Building Path to lab 1381 in the UW Madison Chemistry Building. Created by Software Training for Students at the University of Wisconsin-Madison. http://sts.doit.wisc.edu. By: UW Madison STS … Continue reading

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St Marys Girls School Runda – Ostwald Process (Chemistry) Explained using E-learning platform – Video

Posted: Published on July 9th, 2014

St Marys Girls School Runda - Ostwald Process (Chemistry) Explained using E-learning platform Chemistry Teacher at StMarys Explains the Ostwald Process process during an Elearning symposium for st Marys Girls Rundaand St Annne Lioki. By: St Marys Girls School Runda … Continue reading

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Tactillium: Chemistry. Redefined. – Video

Posted: Published on July 9th, 2014

Tactillium: Chemistry. Redefined. Tactillium does more than offer students an engaging and educational laboratory experience: it brings chemistry into the world of simulated science. Featuring a sophisticated teacher portal,... By: Tactillium … Continue reading

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Irwin Oppenheim passes away

Posted: Published on July 9th, 2014

Irwin Oppenheim passes away Theoretical chemist praised by students and colleagues DEPARTMENT OF CHEMISTRY July 9, 2014 MIT professor emeritus of chemistry Irwin Oppenheim, 84, of Cambridge, passed away on June 3 from complications following cardiac surgery. Oppenheim carried out his undergraduate studies in chemistry and physics at Harvard University, graduating summa cum laude in 1949. He attended graduate school at the California Institute of Technology under John Gamble Kirkwood; when Kirkwood left for Yale University, Oppenheim followed him, completing his PhD in physical chemistry in 1956. His thesis research involved some of the first usage of the Wigner functions and expansion in powers of Plancks constant to develop quantum corrections to classical distribution functions. These distribution functions were then exploited to deduce thermodynamic properties and transport coefficients. Oppenheim joined MITs Department of Chemistry in 1961 as an associate professor notably, its first theoretical chemist. He was promoted to full professor in 1965. Oppenheims research at MIT concentrated on a molecular description of relaxation phenomena in gases and liquids; he, his students, and collaborators made many important contributions to the field. One important contribution is his explanation of the origin of the long time tails unexpectedly observed in early molecular … Continue reading

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Brian Crane named Howard Hughes professor

Posted: Published on July 9th, 2014

July 8, 2014 Brian Crane, professor of chemistry and chemical biology in the College of Arts and Sciences, has been named a Howard Hughes Medical Institute (HHMI) professor, one of 15 leading scientist-educators to receive the honor. Each will receive $1 million over five years to create activities that integrate their research with student learning in ways that enhance undergraduate students understanding of science. Cranes HHMI project will build on Cornells successful prefreshman summer program (PSP) that prepares students for freshman chemistry. He and chemistry professor Stephen Lee, who recently revamped the PSP, will extend the program to prepare the students for more advanced chemistry and then initiate them into research experiences. Too many students who didnt have good preparation in their high schools or are underprepared for other reasons get derailed by weak grades in their first couple of years at Cornell, says Crane. This HHMI professorship gives me the opportunity to organize a program to try and help these students, engage them in science and hopefully send them on to graduate or medical school. Crane explains that the projects classes are based on intense problem-set learning and peer-led group learning, with an emphasis on interactive exercises. The types … Continue reading

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Brian Crane named Howard Hughs professor

Posted: Published on July 9th, 2014

July 8, 2014 Brian Crane, professor of chemistry and chemical biology in the College of Arts and Sciences, has been named a Howard Hughes Medical Institute (HHMI) professor, one of 15 leading scientist-educators to receive the honor. Each will receive $1 million over five years to create activities that integrate their research with student learning in ways that enhance undergraduate students understanding of science. Cranes HHMI project will build on Cornells successful prefreshman summer program (PSP) that prepares students for freshman chemistry. He and chemistry professor Stephen Lee, who recently revamped the PSP, will extend the program to prepare the students for more advanced chemistry and then initiate them into research experiences. Too many students who didnt have good preparation in their high schools or are underprepared for other reasons get derailed by weak grades in their first couple of years at Cornell, says Crane. This HHMI professorship gives me the opportunity to organize a program to try and help these students, engage them in science and hopefully send them on to graduate or medical school. Crane explains that the projects classes are based on intense problem-set learning and peer-led group learning, with an emphasis on interactive exercises. The types … Continue reading

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HPV-targeted adoptive T Cell therapy may provide new strategy for cervical cancer – Video

Posted: Published on July 9th, 2014

HPV-targeted adoptive T Cell therapy may provide new strategy for cervical cancer Visit http://ecancer.org/ for more. At a press conference at ASCO 2014, Dr Hinrichs (Center for Cancer Research, Bethesda, US) presents his work which looks ... By: ecancer medicalscience … Continue reading

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