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Parkinsons disease: genetic defect triggers multiple damages in neurons

Posted: Published on July 7th, 2014

07.07.2014 - (idw) Deutsches Zentrum fr Neurodegenerative Erkrankungen e.V. (DZNE) People whose genome carries certain variations have a particularly high risk of developing Parkinson's disease. In particular, genetic variants in a gene referred to as GBA1 (glucocerebrosidase) are associated to an increased risk for Parkinsons. Researchers of the German Center for Neurodegenerative Diseases (DZNE) and the Hertie Institute for Clinical Brain Research have now pinpointed the consequences that genetic variations in GBA1 have on neurons consequences that had been largely undetermined to date. Using stem cells, they found that mutations affecting GBA1 impair calcium metabolism and the cells garbage disposal that normally digests and recycles defective substances including alpha-synuclein, the protein that accumulates in the brain of patients suffering from Parkinsons. This research shows a link between alterations in the GBA1 gene and cellular dysfunctions in Parkinsons disease for the first time. It also suggests potential targets for drugs and biomarkers that could be useful for diagnosis. The study is published in the journal Nature Communications. In people suffering from Parkinsons, brain cells that are supposed to produce a neurotransmitter called dopamine, die off over time, making it difficult for these patients to control their movements. They may also suffer … Continue reading

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If War should come- DNA Studios – Video

Posted: Published on July 7th, 2014

If War should come- DNA Studios DNA Studios Graduate showcase , Hippodrome Casino Leicester square, London. **NO COPYRIGHT INFRINGEMENT INTENDED*** "This video uses copyrighted material in a manner that does not require... By: Rosina Andrews … Continue reading

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Ravi Shastri with Mir – DNA of a Champion Hangout – Video

Posted: Published on July 7th, 2014

Ravi Shastri with Mir - DNA of a Champion Hangout You are invited to an extraordinary hangout session with Ravi Shastri- "The Champion of Champions" in conversation with Mir Afsar Ali By: NSHM Knowledge Campus … Continue reading

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DNA and WikiTree with Peter J. Roberts – Video

Posted: Published on July 7th, 2014

DNA and WikiTree with Peter J. Roberts Peter J. Roberts, a prominent member of the WikiTree DNA project who has been instrumental in the advancement of DNA tools on our site, will give a general overview of DNA and discuss these... By: WikiTree … Continue reading

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Chemistry Polymers part 10 (Polymer preparation: Step growth)) CBSE class 12 XII – Video

Posted: Published on July 7th, 2014

Chemistry Polymers part 10 (Polymer preparation: Step growth)) CBSE class 12 XII Chemistry Polymers part 10 (Polymer preparation: Step growth)) CBSE class 12 XII. By: ExamFearVideos … Continue reading

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All ENGLAND Players..[99% Chemistry] – Video

Posted: Published on July 7th, 2014

All ENGLAND Players..[99% Chemistry] made with ezvid, free download at http://ezvid.com sorry abt the voice..new headset...not so clear..verry sorry..the link to my previous video(100% chemistry squad) is : http://www.youtube.com/watc... By: umesh 1041 … Continue reading

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Lake Street Dive And The Chemistry Of Harmony

Posted: Published on July 7th, 2014

hide captionLake Street Dive's latest album is Bad Self Portraits. Lake Street Dive's latest album is Bad Self Portraits. Lake Street Dive is two men and two women, all in the neighborhood of 30, who met at the New England Conservatory of Music. As a group they use jazz instrumentation, more or less trumpet, stand-up bass, guitar, some drums but they play pop and soul, and draw a big following doing it. In fact, a video of them performing on a Boston street corner has been viewed more than 2 million times. Listen to the Story: Sold-Out Crowds "If you put background vocals on anything, people are excited about it," drummer Mike Calabrese says, referring to the lush vocal arrangements that dominate the band's latest album, Bad Self Portraits. "There's something about humans singing in harmony that is just inherently joyful." The members of Lake Street Dive spoke with NPR's Steve Inskeep throughout Monday's episode of Morning Edition, touching on their early shows (in which the other bands were sometimes the only audience members) and how they found their pop sound after an experiment with free jazz. Hear more of their stories at the audio links. Excerpt from: Lake Street … Continue reading

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Cell & Gene Therapy International Conference 2014 | Las …

Posted: Published on July 7th, 2014

Theme: Uncover the potential that lies within the cell Welcome Message OMICS is engraving the marks of success in Open Access publishing and International scientific conferences. Inheritance of the research theme and flow of the scientific ideas through organized and clustered scientific session is the key in every OMICS Group conference.OMICS Group have 350leading-edge peer reviewed Open Access Journals and will be organizing over 100International Conferencesannually all over the world. OMICS Publishing Group Journals wrap over3 millionreaders with the well-built editorial board over30000eminent personalities. OMICS Group work together with more than100International Societiesand organizes symposia & workshops at the conferences. OMICS Group Conferences makes a furnish podium for global networking. 3rd InternationalConferenceand Exhibition on Cell & Gene Therapyto be held during October 27-29, 2014 at Las Vegas, USA. Cell Therapy conference is a remarkable event which brings together a unique and International mix of leading Research Scholars, and Scientists achieved eminence in their field of study, research academicians from the universities and research institutions, industrial research professionals and business associates along with Ph.D. Students. The combination of such diverse mix of people but everyone from the scientific field makes the necessary impact for the needed communication. Cell Therapy conference serves and … Continue reading

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What is Bioengineering? – University of California, Berkeley

Posted: Published on July 7th, 2014

Bioengineering is the biological or medical application of engineering principles or engineering equipment also called biomedical engineering. (Merriam-Webster) We like to think of it as the application of engineering principles to biological systems. Bioengineering as a defined field is relatively new, although attempts to solve biological problems have persisted throughout history. Recently, the practice of bioengineering has expanded beyond large-scale efforts likeprostheticsand hospital equipment to include engineering at the molecular and cellular level with applications in energy and the environment as well as healthcare. A very broad area of study, bioengineering can include elements of electrical and mechanical engineering, computer science, materials, chemistry and biology. This breadth allows students and faculty to specialize in their areas of interest and collaborate widely with researchers in allied fields. Graduates are well placed to work in management, production or research and development in a variety of industries such as medical devices, diagnostics, genetics, healthcare industry support, pharmaceutical manufacture, drug discovery, environmental remediation, or agricultural advancement as well as in nonprofit and academic research. Many go on to receive advanced degrees in bioengineering or a related field, or to medical school. Other students find the rigor of bioengineering a useful launching point for careers … Continue reading

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Bioengineering is topic for Cornell Society of Engineers annual conference April 10-12

Posted: Published on July 7th, 2014

ITHACA, N.Y. -- The biological applications of engineering, or bioengineering, is the topic of the 1997 Cornell Society of Engineers annual conference April 10-12 at Cornell University. Featuring Richard A. Hazleton, chairman and CEO of Dow Corning Corp., and Samuel Fleming, chairman and CEO of Decision Resources Inc., the conference "Frontiers in Bioengineering" will highlight research in the rapidly developing field. Featured will be speakers from the Cornell faculty and from industry. Hazleton, the Dow chairman who arrived there in the midst of the silicone breast implant controversy, will give the keynote address, "Science, Public Policy and Ethics in Biomaterials," at a dinner beginning at 7:15 p.m. Friday in the Statler Hotel Terrace Restaurant. Hazleton has appeared frequently on national television and has testified before Congress on the silicone breast implant controversy. The conference kicks off with a talk at 9:25 a.m. Friday, "The Commercial Impact of Biotechnology: What's in Store for the Next 10 Years," by Samuel Fleming (Chem. Eng. '62), chairman and CEO of Decision Resources Inc. His firm, formerly a subsidiary of Arthur D. Little Inc., provides international market forecasting and evaluation for health care, information technology and process industries. His company now has offices on three … Continue reading

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