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Nuclear Transfer Proven An Effective Method In Stem Cell Production

Posted: Published on July 4th, 2014

July 3, 2014 redOrbit Staff & Wire Reports Your Universe Online A new process known as somatic cell nuclear transfer is far better and much more accurate when it comes to coaxing embryonic stem cells out of human skin tissue, according to new research appearing in Tuesdays edition of the journal Nature. Scientists from Oregon Health & Science University (OHSU), the University of California-San Diego (UCSD) School of Medicine and the Salk Institute for Biological Studies created stem cells using two different methods: nuclear transfer, which involves moving genetic material from a skin cell into an empty egg cell, and a more traditional method in which activating a small number of genes reverts adults cells back to an embryonic state. Experts believe that stem cell therapies could someday be used to replace human cells damaged through injury or illness, including spinal cord injuries, diabetes, Parkinsons disease and multiple sclerosis. Human embryonic stem cells (ES cells), which are cells cultured from discarded embryos, are viewed by scientists as the gold standard of the field, and the new study reports that somatic cell nuclear transfer (SCNT) more closely resembled ES cells. This marks the first time that researchers had directly compared the … Continue reading

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Human Stem Cells Lead To Corneal Regrowth, Improved Vision In Mice

Posted: Published on July 4th, 2014

July 3, 2014 Rebekah Eliason for redOrbit.com Your Universe Online In an exciting new study, researchers have discovered a way to collect cells for the regeneration of corneal tissue the clear membrane covering the pupil that directs light into the back of the eye. The research team from Boston reported that purified human stem cells were used to improve long-term vision in mice. Currently, the team is waiting for FDA-approval to begin patient clinical trials. This collaborative research effort was led by Natasha Frank, MD, and Markus Frank, MD, using work done at Massachusetts Eye and Ear/Schepens Eye Research Institute, Boston Childrens Hospital, Brigham and Womens Hospital, and the US Department of Veterans Affairs Boston Healthcare System. In some people blood vessels grow onto the cornea, vision clouding known as corneal blindness results. This condition is caused when limbus stem cells, located behind the cornea, are destroyed by injury, infection or autoimmune disease. Outcomes are inconsistent, but limbal stem cell transplants from an uninjured eye or deceased organ donor have had promising results. Previously published work on limbal epithelial cell grafts showed that when more than three percent of transplanted cells were stem cells, transplants were successfulless than three percent … Continue reading

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Research team pursues techniques to improve elusive stem …

Posted: Published on July 3rd, 2014

Fat cells (yellow) descended from transplanted human mesenchymal stem cells (green) inside of a mouse 28 days after a co-transplantation procedure. The red stain shows mouse fat cells. The blue stain shows cell nuclei. (Credit: Juan Melero-Martin, PhD) Stem cell scientists had what first appeared to be an easy win for regenerative medicine when they discoveredmesenchymal stem cells several decades ago. These cells, found in the bone marrow, can give rise to bone, fat, and muscle tissue, and have been used in hundreds of clinical trials for tissue repair. Unfortunately, the results of these trials have been underwhelming. One problem is that these stem cells dont stick around in the body long enough to benefit the patient. But Harvard Stem Cell Institute (HSCI) scientists atBoston Childrens Hospital arent ready to give up. A research team led by Juan Melero-Martin, PhD, recently found that transplanting mesenchymal stem cells along with blood vessel-forming cells naturally found in circulation improves results. This co-transplantation keeps the mesenchymal stem cells alive longer in mice after engraftment, up to a few weeks compared to hours without co-transplantation. This improved survival gives the mesenchymal stem cells sufficient time to display their full regenerative potential, generating new bone … Continue reading

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Lets Play The Sims 3 Perfect Genetics Part 6: Baby #1 – Video

Posted: Published on July 3rd, 2014

Lets Play The Sims 3 Perfect Genetics Part 6: Baby #1 Watch as the first child is born. Will it be the Perfect Genetic Heir? My Sims 3 Page: http://mypage.thesims3.com/mypage/becky050890 My Husband's Sims 3 Page... By: GBabyChallenger … Continue reading

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The Most Tough German Shepherd Puppy/ Puppy Test/ Top Genetics/ Top Breeding – Video

Posted: Published on July 3rd, 2014

The Most Tough German Shepherd Puppy/ Puppy Test/ Top Genetics/ Top Breeding In this video you see one of my puppies that is 6 weeks old getting tested for the first time. What I am looking for when I am testing a puppy is the top genetic traits. Let me explain to you..I... By: DDRPROGSD1 … Continue reading

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ICGEB 19th symposium 2014 – Video

Posted: Published on July 3rd, 2014

ICGEB 19th symposium 2014 Photos from 19th symposium 2014. By: International Centre for Genetic Engineering and Biotechnology … Continue reading

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Nancy Kress: How Science Fiction Helps Us Rehearse for the Future

Posted: Published on July 3rd, 2014

Stephen Cass: Hello, Im Stephen Cass for IEEE Spectrums Techwise Conversations. Nancy Kress is a celebrated author of science fiction and fantasy novels and short stories. First published in 1976, her work often focuses on the implications of genetic engineering and other biomedical technologies. Among other awards, she has won five Nebulas from the Science Fiction & Fantasy Writers of America. As part of its 50th anniversary celebrations this August, Spectrum will be publishing Coming Soon Enough, an anthology of six original science fiction stories, including one by Kress titled Someone to Watch Over Me. But you dont have to wait to read it: The story is available now as part of Spectrums June special issue about the long-term future of technology. Without giving anything away, Someone to Watch Over Me is a dark tale about the unintended consequences of advanced biomedical implant technology. To talk about the story and the broader themes that run throughout her work, Kress joins us now by phone from her home in Seattle. Nancy, welcome to the podcast. Nancy Kress: Thank you. Im glad to be here. Stephen Cass: So what was the inspiration for Someone to Watch Over Me? Nancy Kress: I often … Continue reading

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Embryology & Fetal Development – Video

Posted: Published on July 3rd, 2014

Embryology Fetal Development A fun play by play of the main changes that we go through as an embryo and fetus, from conception to birth, by batya! By: batya f … Continue reading

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Pregnancies following egg donation associated with more than 3-fold higher risk of hypertension

Posted: Published on July 3rd, 2014

PUBLIC RELEASE DATE: 1-Jul-2014 Contact: Christine Bauquis christine@eshre.eu 32-499-258-046 European Society of Human Reproduction and Embryology Munich, 1 July 2014: With an ever-ageing female patient population, egg donation is an increasingly common treatment in infertility. ESHRE's own annual reports on fertility treatments in Europe show a rise in egg donation cycles from 15,028 in 2007 to 24,517 in 2010 (to 4.05% of all treatments). This proportion is still some way behind the USA, where egg donation now accounts for around 12% of all treatments. As women age their store of viable eggs reduces such that their "ovarian reserve" (and likelihood of pregnancy) declines. Once the eggs have gone, they cannot be replaced, and egg donation is the only possible treatment. In addition, studies consistently show that eggs produced by women in older age groups form embryos with a higher prevalence of chromosome defects than those from younger women: these embryos are less likely to implant and more likely to result in miscarriage if they do implant. As a result, fertility treatment with donor eggs is much more common among older women than among younger. Studies also show that egg donation is an increasingly successful treatment, with live birth rates of … Continue reading

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Most women are aware of oocyte freezing for social reasons

Posted: Published on July 3rd, 2014

PUBLIC RELEASE DATE: 1-Jul-2014 Contact: Christine Bauquis christine@eshre.eu 32-499-258-046 European Society of Human Reproduction and Embryology Munich, 1 July 2014: While the majority of younger women are aware of egg freezing as a technique of fertility preservation and consider it an acceptable means of reproductive planning, only one in five would consider it appropriate for them, according to the results of an internet survey performed in the UK and Denmark. The questionnaire, which was accessible online, was completed anonymously by 973 women with a median age of 31 years between September 2012 and September 2013. Results are reported today at the ESHRE Annual Meeting in Munich by Dr Camille Lallemant of the Complete Fertility Centre of Princess Anne Hospital, Southampton, United Kingdom. " Until very recently, no options for preserving fertility in order to delay childbearing existed," explained Dr Lallemant. "Now, vitrification has revolutionised oocyte freezing and made it effective and convenient. But we are still not clear to what extent women are aware of its possibilities and limitations, or of attitudes towards its use or the circumstances in which they might consider it. Our survey tried to answer these questions."(1) Results showed that the majority of respondents (83%) had … Continue reading

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