Computational Biology using Intel Xeon and Intel Xeon Phi In this video from ISC'14, Christian Blau from the Max Planck Institute and Greg Johnson from Intel describe their demonstration of Computational Biology using Intel Xeon and Intel Xeon Phi. By: RichReport … Continue reading →

Bone Shapes - Drawn and Defined Bone shapes - drawn, defined and discussed! The Human Body is a complex, amazing biological machine.'Human Biology Explained' is a YouTube video series that uses simple drawings to illustrate,... By: Human Biology Explained … Continue reading →

Session 4: Systems Biology Health (Panel Discussion) Session 4: Systems Biology Health (Panel Discussion) - Session Chair: Eric Alm, PhD, Massachusetts Institute of Technology - Peter Turnbaugh, PhD, Harvard FAS Center for Systems Biology -... By: Institute Systems Biology … Continue reading →

Eric Alm, PhD, Massachusetts Institute of Technology The human microbiome in heath and disease Eric Alm, PhD, Massachusetts Institute of Technology Systems Biology the Microbiome | April 15 16, 2012 Institute for Systems Biology Presents... By: Institute Systems Biology … Continue reading →

See Inside A subterranean species that seems to be cancer-proof is providing promising clues on how we might prevent the disease in humans The naked mole rat has been extensively studied, but no cancer has ever been spotted in this species. PHOTOTAKE/ALAMY There is a lot not to envy about the life of the naked mole rat: imagine passing your days in a stuffy, pitch-black system of tunnels two or three metres underground with 100 of your closest relatives. But there is one thing that humans might covet: as far as anyone knows, the animal never gets cancer. Native to the Horn of Africa, this small rodent (Heterocephalus glaber) is neither a mole nor a rat; it is actually more closely related to porcupines and guinea pigs. The animal's pale-pink, wrinkled skin is nearly hairless, the better to slip through those narrow burrows. But there is yet another more compelling fact: in all the thousands of naked mole rats that have lived and died in research labs and zoos over the past several decades, not a single instance of spontaneous cancer has been recorded1. So far, the animal provides little more than a footnote to the vast body of cancer … Continue reading →

2 hours ago Every high school biology student knows the structure of DNA is a double helix, but after DNA is converted into RNA, parts of RNA also commonly fold into the same spiral staircase shape. In a literal scientific twist, researchers are finding examples of a third strand that wraps itself around RNA like a snake, a structure rarely found in nature. Researchers recently have discovered evidence of a triple helix forming at the end of MALAT1, a strand of RNA that does not code for proteins. Yale postdoctoral fellow Jessica Brown and her colleagues working in the labs of Joan A. Steitz and Thomas A. Steitz describe the bonds that maintain the structure of a rare triple helix. This extra strand of RNA, which is seen in the accompanying movie, prevents degradation of MALAT1. The formation of a triple helix explains how MALAT1 accumulates to very high levels in cancer cells, allowing MALAT1 to promote metastasis of lung cancer and likely other cancers. The work is published in the journal Nature Structural and Molecular Biology. Explore further: DNA double helix measurements More information: "Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix." Jessica … Continue reading →