Natural Science Biology Lecture CH 5 Part 8 Genetically Modified Foods By: Amy B Hollingsworth … Continue reading →

Participatory Biology Just as the Internet leveled the playing field for entrepreneurship, politics and social engagement, recent advances are leveling it for biological progress. Processing power, the cloud and... By: Techonomy Media … Continue reading →

Engineering Biology to Address Global Challenges In this video from our June 17 Techonomy Bio conference, Nancy J. Kelley, former founding executive director of the New York Genome Center, gives a presentation of the economic, social, and... By: Techonomy Media … Continue reading →

PUBLIC RELEASE DATE: 12-Jun-2014 Contact: Dr. Esti Yeger-Lotem estiyl@bgu.ac.il 972-864-28675 PLOS A new study published in PLOS Computational Biology shows that genes associated with hereditary diseases occur throughout the human body. The study, by Esti Yeger-Lotem et al., used network biology to model the interactions between proteins associated with diseases such as Parkinson's in different tissues. Using these networks, they show that proteins carrying the disease are found throughout the body. In tissues vulnerable to hereditary diseases, the networked proteins had unique interactions relevant for the mechanism of the disease. Disease causing genes tend to be more highly expressed. The authors demonstrated through several examples that tissue-specific protein interaction can highlight disease mechanisms, and thus, owing to their small number, provide a powerful filter for interrogating the origins of disease. These results offer a powerful filter that can enhance the search for new therapeutic targets for many hereditary diseases. ### All works published in PLOS Computational Biology are open access, which means that everything is immediately and freely available. Use this URL in your coverage to provide readers access to the paper upon publication: http://www.ploscompbiol.org/article/info:doi/pcbi.1003632 Contact: See more here: Hereditary disease genes found throughout the human body … Continue reading →