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Cord blood infusion saves woman's life

Posted: Published on June 17th, 2014

LOS ANGELES (KABC) -- Amanda Canale doesn't take time with her daughter and niece for granted. She's just happy to feel good. "I've been in the hospital, and I've been sick my whole life," Amanda said. Amanda was born with a rare blood disorder that required daily shots. "Basically, I have no white blood cells," Amanda said. "I have no immune system at all." At 23, she developed leukemia and was given two weeks to live. She desperately needed a bone marrow transplant, but family members weren't matches. Her doctor suggested an umbilical cord blood transplant. "The cord was a perfect match and it was available, so it was the right solution for her," Edward Agura, MD, Medical Director of Bone Marrow Transplantation, Baylor University Medical Center, Dallas, said. Cord blood contains stem cells that regenerate. Mothers of newborns can save their child's own blood or donate it. More than 30,000 transplants have been performed worldwide. However, because the blood comes from a tiny newborn, there's not much of it. "The cord blood is rare, precious and few, and yet is more potent in its ability to grow," Dr. Agura said. Now, doctors at Baylor are treating patients by combining … Continue reading →

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Human stem cells implanted in pigs

Posted: Published on June 17th, 2014

Scientists have successfully managed to transfer human stem cells into pigs that have been especially genetically modified for the purpose. The cells thrived following the transplant and researchers believe they are now one step closer to finding treatments for a number of human disease. The rejection of transplanted cells by the host body is one of the major hurdles in stem cell research. By managing to ensure pigs will accept human cells is a huge leap forward in stem cell therapy research, and could lead to treatments for patients with severe immune deficiency. The past research into regenerative medicine has relied on rodent testing, but significant differences in the immune system of mice and people has put limits on the application of the findings. One of the study's authors, Randall Prather, says: "Many medical researchers prefer conducting studies with pigs because they are more anatomically similar to humans than other animals such as mice or rodents. Physically, pigs are much close to the size and scale of humans than other animals, and they respond to health threats similarly. "This means that research in pigs is more likely to have results similar to those in humans for many different tests and … Continue reading →

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Victorian Cosmetic Institute Introduces a Wide Series of Videos on the Latest Anti-Wrinkle Cosmetic Medicine …

Posted: Published on June 17th, 2014

Melbourne, Victoria (PRWEB) June 16, 2014 Victorian Cosmetic Institute is pleased to announce the launch of their wide series of videos on the most advanced cosmetic medicine industry insights and developments. The topics of the videos cover The Golden Ratio - How to not look 'weird' after having cosmetic work, Cosmetic Medicine: where science meets art, The legalities of anti-wrinkle injections & dermal fillers, Anti-Wrinkle Injections: Frequently Asked Questions, and Facial Volume Loss and Dermal Fillers among others. As Dr. Gavin Chan, (MBBS, cosmetic physician, cosmetic surgeon), explains Enhancing and improving your appearance is an important matter. Who you entrust with this responsibility needs to deliver the outcomes you desire whilst providing you with a seamless experience. That is our mission at the Victorian Cosmetic Institute, and we uphold and perpetuate our reputation as 'the place' for cosmetic procedures by delivering this consistently. The Golden Ratio - How to not look 'weird' after having cosmetic work addresses this hot topic while in the video Cosmetic Medicine: where science meets art a Cosmetic Physician throws light upon the art and science of cosmetic medicine, particularly on how it essentially requires a combination of a full medical understanding and an excellent aesthetic … Continue reading →

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Systematic review

Posted: Published on June 17th, 2014

Background Relapsed multiple myeloma has no standard treatment, and the role of autologous stem-cell transplantation (ASCT) has not been fully defined. We aimed to compare high-dose melphalan plus salvage ASCT with cyclophosphamide in patients with relapsed multiple myeloma who had previously undergone ASCT. Between April 16, 2008, and Nov 19, 2012, 297 patients were registered, of whom 293 received PAD re-induction therapy. Between Aug 26, 2008, and Nov 16, 2012, 174 patients with sufficient PBSCs were randomised to salvage ASCT (n=89) or cyclophosphamide (n=85). After a median follow-up of 31 months (IQR 1942), median time to progression was significantly longer in the salvage ASCT than in the cyclophosphamide group (19 months [95% CI 1625] vs 11 months [912]; hazard ratio 036 [95% CI 025053]; p10% of patients) grade 34 adverse events with PAD induction, salvage ASCT, and cyclophosphamide were: neutropenia (125 [43%] of 293 patients after PAD, and 63 [76%] of 83 patients in the salvage ASCT group vs 11 [13%] of 84 patients in the cyclophosphamide group), thrombocytopenia (150 [51%] after PAD, and 60 [72%] vs four [5%], respectively), and peripheral neuropathy (35 [12%] after PAD, and none vs none, respectively). This study provides evidence for the improved efficacy … Continue reading →

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KC area company developing stem cell treatments for pooches – Tucson News Now

Posted: Published on June 17th, 2014

KANSAS CITY, KS (KCTV) - A KCK company is developing a stem cell treatment to help dogs deal with crippling pain from arthritis. Aratana Therapeutics is working to treat osteoarthritis in pets via the stem cell treatment. If the U.S. Food and Drug Administration approves, it would be the first treatment of its kind. The treatment wouldn't provide a cure but would give much-needed relief. "They're still able to move better but they can't do the things they did when they were younger," dog owner Rachel Thieme said. Osteoarthritis can be quite debilitating for canines. "It's really tough because may be there are other areas of quality of life that are fine. They are eating fine. They have that motivation but they just can't physically do anything, so sometimes you have to euthanize them," Thieme said. The only way to cure the condition is to conduct a total joint replacement. But the stem cell procedure hopefully will reduce the need for medications and therapies, said Kara Forsee, a veterinary surgeon for BluePearl Veterinary Partners. Follow this link: KC area company developing stem cell treatments for pooches - Tucson News Now … Continue reading →

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32billion bill for autism, Britain costliest condition: Total cost of treatment, care and support is more then heart …

Posted: Published on June 17th, 2014

London School of Economics and Political Science revealed high costs An estimated 600,000 children and adults in the UK are said to be affected Quarter of sufferers unable to talk, and 85 per cent do not work full time By Jenny Hope Published: 19:37 EST, 9 June 2014 | Updated: 04:40 EST, 10 June 2014 1,062 shares 16 View comments Hugely costly: An estimated 600,000 children and adults in the UK are affected by ASD and genetic factors play a role in its development (file picture) Autism is the most costly medical condition in Britain, say researchers. It costs the UK 32 billion a year - more than heart disease, cancer and stroke combined. Researchers at the London School of Economics and Political Science (LSE) have produced the most comprehensive estimate yet of treatment, lost earnings, care and support costs for children and adults with autism. Originally posted here: 32billion bill for autism, Britain costliest condition: Total cost of treatment, care and support is more then heart ... … Continue reading →

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Levodopa May Beat Newer Meds for Long-Term Parkinson's Care: Study

Posted: Published on June 17th, 2014

WEDNESDAY, June 11, 2014 (HealthDay News) -- When it comes to which drug works best for patients with newly diagnosed Parkinson's disease, older may still be better, a new study finds. Research published June 10 in The Lancet finds that the dopamine drug levodopa still outperforms newer medications for the long-term care of people newly diagnosed with Parkinson's. "This study lays to rest lingering questions among both people with Parkinson's disease and their doctors about which drug is most beneficial when first beginning treatment for the disease," said James Beck, vice president of scientific affairs at the Parkinson's Disease Foundation (PDF). In the largest-ever trial of Parkinson's disease treatment, levodopa offered patients better mobility and a higher quality of life than the two main alternatives -- drugs called dopamine agonists and monoamine oxidase type B (MAO-B) inhibitors. The study included more than 1,600 newly diagnosed Parkinson's disease patients who were randomly selected to take either levodopa or one of the other two treatments. They were followed for up to seven years. "Although the differences in favor of levodopa are small, when you consider the short- and long-term benefits, side effects, quality of life for patients, and costs, the old drug … Continue reading →

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Trust hormone oxytocin helps old muscle work like new, study finds

Posted: Published on June 17th, 2014

BERKELEY UC Berkeley researchers have discovered that oxytocin a hormone associated with maternal nurturing, social attachments, childbirth and sex is indispensable for healthy muscle maintenance and repair, and that in mice it declines with age. The healthy muscle tissue on the left is from a young mouse. The ability of muscle to repair itself decreases with age, as evidenced by the middle image of old muscle tissue, which shows a lower density of muscle fibers, increased scar tissue and inflammation. The addition of oxytocin to the blood of old mice rapidly rejuvenates the old muscle, as shown on the right. (Photos by Wendy Cousin and Christian Elabd, UC Berkeley) The new study, published today (June 10) in the journal Nature Communications, presents oxytocin as the latest treatment target for age-related muscle wasting, or sarcopenia. A few other biochemical factors in blood have been connected to aging and disease in recent years, but oxytocin is the first anti-aging molecule identified that is approved by the Food and Drug Administration for clinical use in humans, the researchers said. Pitocin, a synthetic form of oxytocin, is already used to help with labor and to control bleeding after childbirth. Clinical trials of an oxytocin … Continue reading →

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Mexico boasts a staggering genetic diversity, study shows

Posted: Published on June 17th, 2014

Writers, artists and historians have long pondered what it means to be Mexican. Now science has offered its answer, and it could change how medicine uses racial and ethnic categories to assess disease risk, testing and treatment. The broadest analysis of the Mexican genome ever undertaken reveals a nation of staggering genetic diversity, where European conquest only thinly masks the ancestral DNA of Native Americans, and where some populations remain as distinct from one another as Europeans are from Chinese, according to findings published Thursday in the journal Science. Forty researchers, who share Latino heritage as well as professional qualms over the significance of ethnic and racial categories, teamed up across borders to analyze more than 1 million variations in the building blocks of DNA. They examined more than 500 samples collected in Mexicos remote Indian villages and polyglot cities, and from Mexican Americans in California. Because these populations are so rich, so genetically differentiated, you cant just lump them all in, said lead investigator Carlos Bustamante, a population geneticist and co-director of Stanford Universitys Center for Computational, Evolutionary and Human Genomics. You really have to embrace that diversity and think about doing medical genetic studies on a very large … Continue reading →

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155-Melting DNA – Video

Posted: Published on June 16th, 2014

155-Melting DNA Principles related to denaturation and renaturation of DNA. By: Fundamentals of Biochemistry … Continue reading →

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