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Human stem cells successfully transplanted, grown in pigs

Posted: Published on June 4th, 2014

One of the biggest challenges for medical researchers studying the effectiveness of stem cell therapies is that transplants or grafts of cells are often rejected by the hosts. This rejection can render experiments useless, making research into potentially life-saving treatments a long and difficult process. Now, researchers at the University of Missouri have shown that a new line of genetically modified pigs will host transplanted cells without the risk of rejection. "The rejection of transplants and grafts by host bodies is a huge hurdle for medical researchers," said R. Michael Roberts, Curators Professor of Animal Science and Biochemistry and a researcher in the Bond Life Sciences Center. "By establishing that these pigs will support transplants without the fear of rejection, we can move stem cell therapy research forward at a quicker pace." In a published study, the team of researchers implanted human pluripotent stem cells in a special line of pigs developed by Randall Prather, an MU Curators Professor of reproductive physiology. Prather specifically created the pigs with immune systems that allow the pigs to accept all transplants or grafts without rejection. Once the scientists implanted the cells, the pigs did not reject the stem cells and the cells thrived. … Continue reading →

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Insception Lifebank Cord Blood Program Launches Cord Tissue Banking

Posted: Published on June 4th, 2014

Toronto, Canada (PRWEB) June 04, 2014 Insception Lifebank, Canada's largest cord blood program, now offers expecting parents the option to bank a section of the actual umbilical cord tissue, in addition to banking cord blood. "With exciting developments in stem cell research, scientists continue to identify different types and sources of stem cells that offer therapeutic promise," said Richard Lockie, President and CEO of Insception Lifebank. "The umbilical cord tissue is a rich source of Mesenchymal Stem Cells (MSCs), which are different from the stem cells obtained in cord blood collection." For the past 17 years, Insception Lifebank has focused on umbilical cord blood stem cells, which are used today in the treatment of over 80 life-threatening diseases, and are being investigated in clinical trials involving Autism, Cerebral Palsy, and Pediatric Brain Injury. In contrast, "MSCs can inhibit inflammation, suppress an immune response, aid in tissue repair, and differentiate into structural tissue including bone and cartilage," explains Dr. Ian Rogers of the Lunenfeld-Tanenbaum Research Institute. Because of their versatility, MSCs are being investigated to treat a variety of therapeutic areas including Heart Failure, Stroke, Rheumatoid Arthritis, Multiple Sclerosis and many more. The application of cord tissue MSCs is in the … Continue reading →

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Unlocking the potential of stem cells to repair brain damage

Posted: Published on June 4th, 2014

PUBLIC RELEASE DATE: 3-Jun-2014 Contact: Sandra Hutchinson s3.hutchinson@qut.edu.au 61-731-389-449 Queensland University of Technology A QUT scientist is hoping to unlock the potential of stem cells as a way of repairing neural damage to the brain. Rachel Okolicsanyi, from the Genomics Research Centre at QUT's Institute of Health and Biomedical Innovation, said unlike other cells in the body which were able to divide and replicate, once most types of brain cells died, the damage was deemed irreversible. Ms Okolicsanyi is manipulating adult stem cells from bone marrow to produce a population of cells that can be used to treat brain damage. "My research is a step in proving that stem cells taken from the bone marrow can be manipulated into neural cells, or precursor cells that have the potential to replace, repair or treat brain damage," she said. Ms Okolicsanyi's research has been published in Developmental Biology journal, and outlines the potential stem cells have for brain damage repair. "What I am looking at is whether or not stem cells from the bone marrow have the potential to differentiate or mature into neural cells," she said. "Neural cells are those cells from the brain that make everything from the structure of … Continue reading →

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First demonstration in human cells of chromosomal translocations that cause certain cancer

Posted: Published on June 4th, 2014

PUBLIC RELEASE DATE: 4-Jun-2014 Contact: Ainhoa Iriberri airiberri@cnic.es 34-610-295-556 Centro Nacional de Investigaciones Cardiovasculares Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Centro Nacional de Investigaciones Oncolgicas (CNIO) have succeeded in reproducing, in human cells, the chromosomal translocations that cause two types of cancer: acute myeloid leukemia and Ewing's sarcoma. The findings, published today in Nature Communications, open the way to the development of new therapeutic targets for the treatment of these cancers. The study was led by Juan Carlos Ramrez and Ral Torres, of the CNIC Viral Vectors Unit, and Sandra Rodrguez-Perales, of the Molecular Cytogenetics group at the CNIO, directed by Juan Cruz Cigudosa. The research team used innovative technology to demonstrate that it is possible to reproduce chromosomal modifications in human cells that are identical to the modifications observed in leukemias and other types of cancer. The new technology, which uses molecular tools to manipulate the genome, has two main advantages. First, it allows researchers to generate previously unavailable cell models for the study of tumor biology. And second, future development will allow the study of new therapeutic targets and therapies. The development of tumors is caused by multiple changes in cell physiology and … Continue reading →

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Bionic Eye

Posted: Published on June 4th, 2014

This film will soonbe available to watch online. Please see information below to watch it on the Al Jazeera English channel. "On November the second on a Saturday, she was sitting at the dinner table and I was sitting here and I saw her It was a very special moment." This was the first time Fred van Rennes saw his wife after losing his sight around 20 years ago. Fred went blind at the age of 34 due to a degenerative eye disease called retinitis pigmentosa, a condition in which the photoreceptors in the eye stop working properly. But a ground-breaking new 'bionic eye' called the Argus II Retinal Prosthesis System is helping Fred and others suffering from retinitis pigmentosa to see shapes and patterns for the first time in decades. The device is made up of a miniature camera placed on a pair of glasses and electrodes which are surgically implanted on the patient's damaged retina. The camera sends wireless signals to the electrodes, which in turn send small pulses of electricity down the optical nerve to the brain, which slowly learns to interpret the pulses as visual patterns. Dr Javid Abdelmoneim travels to Amsterdam, the Netherlands, to see … Continue reading →

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102.35 /$ (5 p.m.)

Posted: Published on June 4th, 2014

TSUKUBA, IBARAKI PREF. Unlike many free climbers, Koichiro Kobayashi does not consider the view from the top to be the highlight of scaling a cliff. Unable to enjoy such vistas due to a severe visual impairment, Kobayashi, 46, feels a sense of achievement from completing a task that would be challenging even to those with perfect vision. An enthusiastic climber from the age of 16, Kobayashi completed several major climbs overseas after starting university. After finishing school, he worked as a canoeing guide at an outdoor sports company and climbed every weekend. But his future suddenly looked hopeless when a doctor informed him he was suffering from an inherited, degenerative eye disease called retinitis pigmentosa which would eventually leave him blind. That was at age 28. Since then, Kobayashi has been losing his eyesight little by little and now can only sense light. For the next three years after being diagnosed, Kobayashi forgot about free climbing and focused on concerns about his future. When he was 31, however, he met a caseworker who encouraged him to take the sport up again, saying, It is important to think what you want to do in the future, not what you cant. Kobayashi … Continue reading →

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Stem cell Transplant+AMT with voice June 2014 – Video

Posted: Published on June 4th, 2014

Stem cell Transplant+AMT with voice June 2014 Case of 360 degrees stem cell deficiency due to chemical burns (old). Autologous stem cell transplant taken from patient's other eye (unaffected) and sutured... By: Quresh Maskati … Continue reading →

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Using stem cells, woman joins brothers cancer fight

Posted: Published on June 4th, 2014

GOLTRY, Okla. Armed with stem cells, a Goltry area woman will be heading to Milwaukee next week to join in her brothers cancer fight. Jeni Sumner was the only match among family members tested to donate stem cells to her younger brother, Ed Dee. To me, Ive been given a gift. I know everybodys congratulating me and saying its a wonderful thing, and not taking it away from that, but I think Ive been given just a tremendous gift, Sumner said. Along with helping her brother, Sumner is trying to encourage others to join the bone marrow donor registry. I think a lot of people are afraid to join because they might get called, because they dont know what its like to be a donor, she said. I want more people to become aware of what its actually like to be a donor. Sumner set up a Facebook page It Doesnt Hurt - To Save a Life to chronicle everything she will go through, as a donor, during the procedure. Its an unknown for me, but its nothing compared to what my brothers going through, she said. I know the feeling that I got when I got the call from … Continue reading →

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Breast Reconstruction Columbus Options – Midwest Breast – Video

Posted: Published on June 4th, 2014

Breast Reconstruction Columbus Options - Midwest Breast Breast reconstruction is a type of surgery for women who have had a breast(s) removed (often due to breast cancer). Many women eligible for breast reconstruc... By: Midwest Breast Aesthetic Surgery … Continue reading →

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Artificial blood made from human stem cells could plug the donations hole

Posted: Published on June 4th, 2014

"It's a tiny wee finger prick test," says senior nurse Patsy Scouse to calm the nervous first-time donor having his hemoglobin levels tested at a blood donation centre in Edinburgh. The Scottish National Blood Transfusion Service receives donations from about four percent of the UK's population. Currently, stocks are stable, although the service is always trying to recruit new donors. The collection may take place in a clinical environment, the nurse says, but the clinic "wants this experience, especially for first-time donors, to be really positive so they can go out and feel they've done a really good thing." But the service is also working on potential new technologies to secure blood supplies in the future, including "artificial blood." Mass-produced and clean Mark Turner, medical director of the Blood Transfusion Service, is looking into how blood could be synthesized in the future. "We've known for some time that it's possible to produce red blood cells from so called adult stem cells, but you can't produce large amounts of blood in that way because of the restrictive capacity of those cells to proliferate," he explains. What scientists can do, he adds, is to derive pluripotent stem cells - stem cell lines … Continue reading →

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