April was Parkinson's Awarness Month, but here at ThirdAge we want to promote PD awarness all year long. To that end, here's a fascintating and encouraging new study about PD. In Parkinson's disease, dopamine-producing nerve cells that control movements waste away. Current treatments for PD aim at restoring dopamine contents in the brain. Now researchers at Lund University in Sweden are attacking the problem from a different angle. Ther are experimenting with early activation of a protein that improves the brain's capacity to cope with a host of harmful processes. Stimulating the protein that is called Sigma-1 receptor sets off a battery of defense mechanisms and restores lost motor function. The results were obtained in mice, but clinical trials in patients may not be far away. A release from the university notes that by activating the Sigma-1 receptor, , levels of several molecules that help nerve cells build new connections were increased, inflammation was decreased, and dopamine levels also rose. The results, published in May 2014 the journal Brain, show a marked improvement of motor symptoms in mice with a Parkinson-like condition that had been treated with a Sigma-1-stimulating drug for 5 weeks. This treatment has never before been studied … Continue reading
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