Home > News > world-news Washington, May 16 : Mice severely disabled by a condition that was similar to multiple sclerosis (MS) were able to walk less than two weeks following treatment with human neural stem cells. In striking contrast to active, healthy mice, those with an MS-like condition must be fed by hand because they cannot stand long enough to eat and drink on their own. When scientists transplanted human neural stem cells into the MS mice, they expected no benefit from the treatment. They thought the mice would reject the cells, much like rejection of an organ transplant. Co-senior author, Tom Lane, Ph.D., a professor of pathology at the University of Utah, said my postdoctoral fellow Dr. Lu Chen came to me and said, 'The mice are walking.' I didn't believe her. He began the study with co-first author Chen at the University of California, Irvine. Within a remarkably short period of time, 10 to 14 days, the mice had regained motor skills. Six months later, they showed no signs of slowing down. The findings have been published online in the journal Stem Cell Reports. --ANI (Posted on 16-05-2014) Share this Post: Post Your Comments See the original … Continue reading →

Treatment with human stem cells has allowed mice crippled by a version of multiple sclerosis to walk again after less than two weeks. Scientists admit to being astonished by the result and believe it opens up a new avenue of research in the quest for solutions to MS. Prof Tom Lane, from the University of Utah, who led the US team, recalled: My postdoctoral fellow Dr Lu Chen came to me and said the mice are walking. I didnt believe her. The mice had a condition that mimics the symptoms of human MS. They were so disabled they could not stand long enough to eat and drink and had to be hand-fed. The scientists transplanted human neural stem cells into the mice expecting them to be rejected. But within 10 to 14 days, the mice had regained motor skills and were able to walk again. Six months later, they showed no sign of relapsing. The findings, published in the journal Stem Cell Reports, suggest the mice experienced at least a partial reversal of their symptoms. A similar outcome in humans could help patients with potentially disabling progressive stages of the disease for which there are no treatments. This result opens … Continue reading →

Mice severely disabled by a multiple sclerosis (MS) -- like condition could walk less than two weeks following treatment with human stem cells. The finding, which uncovers new avenues for treating MS, will be published online on May 15, 2014, in the journal Stem Cell Reports. When scientists transplanted human stem cells into MS mice, they predicted the cells would be rejected, much like rejection of an organ transplant. Expecting no benefit to the mice, they were surprised when the experiment yielded spectacular results. "My postdoctoral fellow Dr. Lu Chen came to me and said, 'The mice are walking.' I didn't believe her," said co-senior author, Tom Lane, Ph.D., a professor of pathology at the University of Utah, who began the work at University of California, Irvine. Within just 10 to 14 days, the mice regained motor skills. Six months later, they still showed no signs of slowing down. "This result opens up a whole new area of research for us," said co-senior author Jeanne Loring, Ph.D., co-senior author and professor at The Scripps Research Institute in La Jolla, Calif. More than 2.3 million people worldwide have MS, a disease where the immune system attacks myelin, an insulation layer surrounding … Continue reading →