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MP Catherine McKinnell backs the MS Societys Treat Me Right campaign

Posted: Published on May 4th, 2014

The MP for Newcastle North has signed up to the MS Society's campaign Catherine McKinnell, MP for Newcastle North, is backing the MS Societys Treat Me Right campaign, which is calling for fair and equal access to the right treatment at the right time for people with multiple sclerosis (MS). The MP, who is a member and former Chair of the All-Party Parliamentary Group on MS, was honoured this week to be invited to be the president of the Newcastle and Gateshead branch of the MS Society. She signed up to the MS Societys campaign at an event in Parliament to mark MS Week, taking place this month. As part of the campaign, the MS Society is warning that thousands of people with MS could be left behind as new NHS medicines emerge that are out of reach for many with the condition. The charity estimates a quarter of all people with MS in the UK around 27,000 people might begin taking a licensed disease modifying drug (DMD) if care was consistent and all people with MS had access to appropriate information and support to make decisions about their care. There are now nine MS drugs approved for use on … Continue reading →

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The test for everything

Posted: Published on May 4th, 2014

In the course of his early research, the chief scientific officer of Genome BC routinely drew his own blood to compare with the DNA of people who were known to have disorders such as cystic fibrosis or spinal cerebral ataxia. "I would draw blood weekly ... and provide that to extract DNA," said Brad Popovich. "The reason I was very comfortable doing that is that knew I didn't have any one of those diseases. So, I was a good control." But over all those years, dating back to the late 1980s, Popovich never allowed his DNA to be tested for the APOE e4 gene. Having a single copy of the APOE e4 gene increases the carrier's risk of late-onset Alzheimer's disease. Having two copies - the e4e4 configuration - dramatically increases the risk yet again. "I basically said to the lab: 'I'm not a control for that test, I don't want you ever to use me as a control for that test, because I don't want to know and I don't want you to know if I have that,'" he recalled. "Both my maternal grandmother and my mom died of dementia and so there was a significant risk there," said … Continue reading →

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For the first time, proof of what hormone replacement therapy does to genes involved in breast cancer

Posted: Published on May 4th, 2014

Researchers have measured activity of genes associated with breast cancer in women before and while, they took different types of HRT. They found that an HRT used in the WHI trial had a greater activating effect on these genes than a "natural" formulation applied via an estrogen gel applied to the skin in combination with oral progesterone. This shows that varying the HRT and the way it is taken can have very significant effects on the genes associated with breast cancer. New research has found that the type of HRT a woman takes, and the way it is taken, can have a significantly different effect on genes associated with breast cancer. This finding, presented at the World Congress on the Menopause in Cancun, Mexico, opens the way to identify which forms of HRT have minimal effect on breast cancer. It also gives the long-term possibility of personalising HRT according to the genes which a woman expresses. Since the publication of the Women's Health Initiative report on HRT in 2002, many women have been worried about the effect of HRT on breast cancer. The International Menopause Society states that the increase in breast cancer is small, but that recommends that HRT … Continue reading →

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Stem Cells 101 and Beyond – Video

Posted: Published on May 4th, 2014

Stem Cells 101 and Beyond Divya Mathur and Chris Lengner from Rudolf Jaenisch's lab at the Whitehead Institute discuss the basics of stem cell research, as well as their latest findings. By: Forum Network … Continue reading →

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Only 3 stem cell procedures allowed in PH – FDA

Posted: Published on May 4th, 2014

MANILA - Only three stem cell procedures are now allowed in the Philippines as the Food and Drug Administration (FDA) rejected the registration of other stem cell products. FDA director general Kenneth Hartigan-Go said only the use of stem cells in hematopoietic transplantation, corneal resurfacing with limbal stem cells, and skin regeneration with epidermal stem cells are recognized by the FDA as acceptable or standard healthcare procedures. Go said other stem cell therapies are considered illegal. In an advisory, Go also said that not one stem cell or tissue-based product (HCT/Ps) had been registered by the FDA for compassionate or clinical trial use or for general use. Those who want to do stem cell outside of the three approved indications will have to register, either for compassionate use or clinical trial (as) these are the ones we inspect, he added. The FDA official cited lack of evidence of technical competence, procedures and documentations based on Current Good Manufacturing Practices and Current Good Laboratory Practices in denying the applications. The applications also did not have ethical review procedures and systems accredited by the Philippine Health Research Ethics Board, the national accreditation body of the Department of Science and Technology, and had … Continue reading →

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Scientists Produce Personalized Stem Cells For Specific Diseases

Posted: Published on May 4th, 2014

By Estel Grace Masangkay An independent group of scientists led by experts at the New York Stem Cell Foundation Research Institute (NYSCF) reported that they have manufactured the first disease-specific line of embryonic stem cells made with a patients DNA. The achievement is heralded as a major breakthrough in the regenerative medicine field. This is also the first time cloning technologies have been utilized to generate genetically matched stem cells. The team used somatic cell nuclear transfer to successfully clone a skin cell from a 32 year old female patient with Type 1 diabetes. The cells were transformed into insulin-producing cells similar to lost beta cells in diabetes, which could provide better treatment or even a cure for T1D. Susan Solomon, CEO and co-founder of NYSCF, says she is excited about the successful production of patient-specific stem cells using somatic cell nuclear transfer (SCNT). CEO Solomon said she became involved with medical research when her son was diagnosed with T1D. Dr. Egli, scientist from the New York Stem Cell Foundation Research Institute and who led the research, said, From the start, the goal of this work has been to make patient-specific stem cells from an adult human subject with type-1 … Continue reading →

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Karen's Stem Cell Transplant, Time Lapse – Video

Posted: Published on May 3rd, 2014

Karen's Stem Cell Transplant, Time Lapse Note the 6 bags of cells draining. 4.24 million stem cells, harvested over four days Shoot with my inexpensive but excellent chinese mini-cam: http://www.ama... By: Mako Koiwai … Continue reading →

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Barb's Stem Cell Transplant – Video

Posted: Published on May 3rd, 2014

Barb's Stem Cell Transplant http://www.GoFundMe.com/BarbBoarts http://www.CaringBridge.org/visit/BarbBoarts Barb's allogeneic stem cell transplant was performed on April 29, 2014 at UPMC Shadyside in... By: Team Barb Boarts … Continue reading →

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Dr. Grant Stevens discusses innovations in aesthetic surgery with ASJ. – Video

Posted: Published on May 3rd, 2014

Dr. Grant Stevens discusses innovations in aesthetic surgery with ASJ. Dr. Grant Stevens tells Phaedra Cress, Executive Editor of ASJ, about the innovations in aesthetic surgery we can expect in the future. By: ASJOnline … Continue reading →

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Legislature could boost U stem cell research

Posted: Published on May 3rd, 2014

The future of the University of Minnesotas regenerative medicine research program is looking brighter than ever. State and federal leaders in the past have denied funding for the Universitys Office of Regenerative Medicine, which includes the Stem Cell Institute, because some had ethical disagreements with stem cell research. But this legislative session, with a DFL majority and an overall shift in public opinion, researchers and legislators are confident funding will come through this year. The current House bill sets aside $450,000 for the Office of Regenerative Medicine, while the Senate version outlines a $5 million increase each year from 2015-17. The bills texts dont specify how funds should be used and how they would be divided between the University and the Mayo Clinic, its research partner. The Senates bill mandates that anadvisory task force comprised of members from the University, the Mayo Clinic and private industry, as well as two other regenerative medicine experts, recommend how to spend the state funding. Dayton didnt include funds for the research in his original budget proposal this year, but Sen. Terri Bonoff, DFL-Minnetonka, said there seems to be a general consensus among legislators to work together and decide on a funding amount. I … Continue reading →

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