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Cloning: Scientists make insulin-producing cells

Posted: Published on April 29th, 2014

It was not the first study to create stem cells in this way, but it was the first to use cells sourced from a diseased adult person with the aim of producing therapy-specific cells. FEATURE Scientists said yesterday they had used cloning technology to make embryonic stem cells that carry a diabetic womans genes, and turned them into insulin-producing beta cells that may one day cure her disease. The team reported clearing an important hurdle in the quest to make personalised stem cells for use in disease therapy, but a bioethicist said the breakthrough also highlighted the need for better regulation of lab-grown embryos. We are now one step closer to being able to treat diabetic patients with their own insulin-producing cells, said Dieter Egli of the New York Stem Cell Foundation (NYSCF), who led the study published in the journal Nature. Egli and a team had transplanted the nuclei of cells taken from the womans skin into human eggs to create stem cells, which they could then coax into becoming beta cells a shortage of which causes insulin deficiency and high blood-sugar in diabetics. In doing so, the team confirmed a potentially important source for future cell-replacement therapy. It … Continue reading →

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How human cloning could cure diabetes

Posted: Published on April 29th, 2014

"From the start, the goal of this work has been to make patient-specific stem cells from an adult human subject with type 1 diabetes that can give rise to the cells lost in the disease. Patients with type 1 diabetes lack insulin-producing beta cells, resulting in insulin deficiency and high blood-sugar levels. Because the stem cells are made using a patient's own skin cells, the engineered cells for replacement therapy would matching the patient's DNA and so would not be rejected. It is hoped that in future the stem cell therapy could be used for a wide range of conditions including Parkinson's disease, macular degeneration, multiple sclerosis, and liver diseases and for replacing or repairing damaged bones. "I am thrilled to say we have accomplished our goal of creating patient-specific stem cells from diabetic patients using somatic cell nuclear transfer," said Susan Solomon, CEO and co-founder of NYSCF whose own son is Type-1 diabetic. "Seeing today's results gives me hope that we will one day have a cure for this debilitating disease. The technique works by removing the nucleus from an adult oocyte an early stage egg - and replacing it with the nucleus of a healthy infant skin cell. … Continue reading →

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Meet Pamela The MS Stem Cell Transplant Girl – Video

Posted: Published on April 29th, 2014

Meet Pamela The MS Stem Cell Transplant Girl By: MS Stem Cell Transplant Girl … Continue reading →

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Cerebral Palsy (CP) Stem Cell Transplant at Egypt – Video

Posted: Published on April 29th, 2014

Cerebral Palsy (CP) Stem Cell Transplant at Egypt Dr. Amr Kahlil is a consultant orthopedic, who works on his own stem-cells research in the last decade. He tried his new technique of Stem cell therapy on 13... By: Amr Khalel … Continue reading →

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Cloning used to make stem cells from adult humans in diabetes breakthrough

Posted: Published on April 29th, 2014

Researchers say technique could first be used as a way to treat diabetes Used cloning technique to make insulin-producing cells with the DNA of a diabetic woman Second cloning experiment to make stem cells in a month By Mark Prigg Published: 16:00 EST, 28 April 2014 | Updated: 22:12 EST, 28 April 2014 227 shares 15 View comments Scientists have moved a step closer to the goal of creating stem cells perfectly matched to a patient's DNA in order to treat diseases. New York researchers used a cloning technique to make insulin-producing cells with the DNA of a diabetic woman. They used used skin cells from the 32-year-old woman with Type 1 diabetes to generate stem cells matched to her. Researchers used used skin cells from the 32-year-old woman with Type 1 diabetes to generate this colony of an embryonic stem cell line. Visit link: Cloning used to make stem cells from adult humans in diabetes breakthrough … Continue reading →

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Potential diabetes therapy: scientists grow insulin-producing cells using cloning techniques

Posted: Published on April 29th, 2014

April 29, 2014, 8:21 a.m. For the first time scientists have used cells from a woman with type 1 diabetes to create cloned human embryos from which they extracted embryonic stem cells. For the first time scientists have used cells from a woman with type 1 diabetes to create cloned human embryos from which they extracted embryonic stem cells. The American-Israeli team also coaxed the stem cells into insulin-producing beta cells, the kind lost in patients with type 1 diabetes. "These stem cells could therefore be used to generate cells for therapeutic cell replacement," research leader Dieter Egli, from the New York Stem Cell Foundation Research Institute, said. Embryonic stem cells are capable of transforming into any tissue in the body, not just insulin-producing cells. Therein lies their medical potential to regenerate tissue or organs for transplant. The benefit of stem cells obtained from cloned human embryos is they are genetically matched to the person who donated the adult cell, meaning they could be used to personalise therapies for a range of crippling diseases, not just diabetes. But somatic cell nuclear transfer the technique used to create Dolly the sheep is ethically controversial in humans because it involves the creation … Continue reading →

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Can looks help you climb ladder?

Posted: Published on April 29th, 2014

Tue, Apr 29, 2014 by Carolyn Khew It has always been whispered around offices, but a local study now claims there is evidence to show that good looks can help you snag that job or that promotion. One caveat: The survey was conducted by the Society of Aesthetic Medicine (Singapore) and sponsored by Allergan, the maker of Botox, who can hardly claim to be uninterested parties. It found that roughly eight out of 10 respondents felt that physically attractive people are more likely to be hired and promoted. Almost seven out of 10 know of someone who was hired or promoted because of their good looks. An overwhelming nine out of 10 also felt that good-looking people are more likely to be called for job interviews based on photographs in resumes. The online survey conducted last month polled 500 employees between 30 and 60 years old. Most of those surveyed were women (eight out of 10) and all participants earned over $3,000 a month. Interestingly, despite the identity of the parties behind the survey, psychologists and recruitment firms did not dismiss the findings, even though they pointed out that being physically attractive and looking presentable were two different things. David … Continue reading →

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Dr. Laurie Casas for Aesthetic Surgery Journal (ASJ) – Video

Posted: Published on April 29th, 2014

Dr. Laurie Casas for Aesthetic Surgery Journal (ASJ) Dr. Foad Nahai Interviews Dr. Laurie Casas about the "Mommy Makeover". By: ASJOnline … Continue reading →

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Stem Cells Made from Cloned Human Embryos

Posted: Published on April 29th, 2014

Cell lines made by two separate teams could boost the prospects of patient-specific therapies This colony of embryonic stem cells, created from a type 1 diabetes patient, is one of the first to be cloned from an adult human. Credit:Bjarki Johannesson, NYSCF Two research groups have independently produced human embryonic stem-cell lines from embryos cloned from adult cells. Their success could reinvigorate efforts to use such cells to make patient-specific replacement tissues for degenerative diseases, for example to replace pancreatic cells in patients with type 1 diabetes. But further studies will be needed before such cells can be tested as therapies. The first stem-cell lines from cloned human embryos were reported in May last year by a team led by reproductive biology specialist Shoukhrat Mitalipov of the Oregon Health & Science University in Beaverton (see 'Human stem cells created by cloning'). Those cells carried genomes taken from fetal cells or from cells of an eight-month-old baby, and it was unclear whether this would be possible using cells from older individuals. (Errors were found in Mitalipov's paper, but were not deemed to affect the validity of its results.) Now two teams have independently announced success. On 17 April, researchers led by … Continue reading →

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Stem cells made by cloning adult humans

Posted: Published on April 29th, 2014

Bjarki Johannesson, NYSCF This colony of embryonic stem cells, created from a type 1 diabetes patient, is one of the first to be cloned from an adult human. Two research groups have independently produced human embryonic stem-cell lines from embryos cloned from adult cells. Their success could reinvigorate efforts to use such cells to make patient-specific replacement tissues for degenerative diseases, for example to replace pancreatic cells in patients with type 1 diabetes. But further studies will be needed before such cells can be tested as therapies. The first stem-cell lines from cloned human embryos were reported in May last year by a team led by reproductive biology specialist Shoukhrat Mitalipov of the Oregon Health & Science University in Beaverton (see 'Human stem cells created by cloning'). Those cells carried genomes taken from fetal cells or from cells of an eight-month-old baby1, and it was unclear whether this would be possible using cells from older individuals. (Errors were found in Mitalipov's paper, but were not deemed to affect the validity of its results.) Now two teams have independently announced success. On 17 April, researchers led by Young Gie Chung and Dong Ryul Lee at the CHA University in Seoul reported … Continue reading →

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