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Blood Pressure Drug Found To Prevent Epilepsy After Brain Injury

Posted: Published on April 28th, 2014

By Marcus Johnson A common blood pressure drug, Cozaar (losartan), has been found to prevent epilepsy and impede further brain damage caused by seizures in patients that already have epilepsy. It is estimated that between 10 to 25 percent of all epilepsy attacks are a direct result of serious head trauma. Seizures caused by epilepsy can create further brain damage and worsen current brain injuries. Dr. Daniela Kaufer of the University of California is excited about the results of the current study, saying, This study for the first time offers a new mechanism and an existing, FDA-approved drug to potentially prevent epilepsy in patients after brain injuries and once they develop an abnormal blood-brain barrier, said Kaufer. Researchers at the University of California at Berkeley, Charit-University Medicine in Germany, and Ben-Gurion University in Negev completed an animal study on rats to come to the findings. In rats with extreme head trauma, the drug was able to prevent seizures in 60 percent of those treated. The remaining 40 percent had seizure rates of one quarter of those typical for rats who were not treated. The treatment regimen lasted 3 weeks and prevented seizures for the following few months. Human based clinical … Continue reading →

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Upper Southampton zoning hearing concludes for proposed traumatic brain injury center

Posted: Published on April 28th, 2014

By Greg Vellner 21st Century Media News Service The Upper Southampton Township Zoning Hearing Board, host of three hours-long vocal hearings, is expected to render a decision within 45 days. The board must decide if Delaware Valley Residential Care of Chalfont can construct and operate a two-story, 16,000-square-foot facility on a vacant 6.5-acre tract zoned Residential at 1216 Street Road. The planned facility also is to include five 4,200-square-foot, single-story buildings to house a maximum of 40 traumatic brain injury patients, ages 18 and older. In hearings begun in January, irate homeowners from an adjacent singe-family development shouted down the plan. Some said it would lessen property value, while others said TBI patients were not normal and pose a danger to the community. Some called the plan an unadulterated nightmare and said they feared TBI patients might wander from the center into the neighborhood. The center is planned along the south side of Street Road, east of the Southampton Post Office and next to a restaurant/bar. Ian Yannuzzi, executive director of DVRC, said he is confident the center will gain zoning board approval. Were very satisfied with our presentation, he said. We feel were within all the requirements. The proposal … Continue reading →

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PharmaPoint: Schizophrenia US Drug Forecast and Market Analysis to 2022

Posted: Published on April 28th, 2014

NEW YORK, April 28, 2014 /Emag.co.uk/ Reportlinker.com announces that a new market research report is available in its catalogue: PharmaPoint: Schizophrenia US Drug Forecast and Market Analysis to 2022 Summary Schizophrenia is a persistent long-term brain disorder that causes severe, debilitating psychotic episodes. Its core symptoms, auditory or visual hallucinations, are often accompanied by fixed, false, and often paranoid beliefs, called delusions. These two features are often combined with learning and cognitive deficits. WHO experts have estimated that roughly 24 million people are affected by schizophrenia worldwide. While the arrival of atypical antipsychotics has greatly expanded pharmacologic treatment options over the past two decades, the current drug market does not treat the negative and cognitive symptoms that are associated with the disease. GlobalData expects that the growing popularity of long-acting injectable (LAI) antipsychotics, along with the arrival of novel treatments that achieve higher efficacy in negative- and cognitive-predominant patients, will serve to stimulate growth in the marketplace over the forecast period. Country-specific treatment recommendations and policy implementation will be an essential metric for determining future mental health services in the 7MM. Mental health is a major focus of the recent healthcare policy in the US. Conditions such as Alzheimers disease … Continue reading →

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'Shameful' failings mean half of MS sufferers denied drugs

Posted: Published on April 28th, 2014

Michelle Mitchell, the charitys chief executive said: We understand the pressures the NHS is facing, but there are licensed medicines that can transform the lives of people with MS, and its frankly shameful that they are out of reach for so many. The charity said many patients were left for years without any treatment at all, as their disease worsens, unaware of new medicines which could reduce the frequency and severity of attacks and in some cases slow the progression of disability. The letter warns that despite a number of recent advances in medicines for the condition, which affects around 85,000 people in Britain, the UK is among the worst in Europe at providing them. It is signed by 26 celebrity supporters of the MS Society, including the explorer Sir Ranulph Fiennes, the actor David Tennant and the television presenter Lorraine Kelly. Two new medicines - Aubagio and Lemtrada - have recently been recommended by NHS rationing bodies as the first line treatment for those with the condition, and decisions on two more treatments are due within a year. Mrs Mitchell said that despite advances in medicines, many sufferers faced barriers accessing treatment which could improve the quality of their … Continue reading →

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New MS drugs 'out of reach'

Posted: Published on April 28th, 2014

Published Monday, 28 April 2014 The MS Society is asking people with MS to review their treatment options. (UTV) Recent estimates suggest that there are more than 4,000 people living with MS in Northern Ireland - one of the highest prevalence rates in the world. Research published by the charity in 2013 found that access to existing MS treatments was substantially higher in Northern Ireland than in the rest of the UK. However the MS Society said there are concerns that new, life-changing MS drugs are still out of reach for many in NI. There are now nine MS drugs approved for use on the NHS, but many with MS are not taking any treatment and are in the dark about the drugs that have the potential to alter the devastating impact of their condition. The news comes as two new, innovative MS medicines have recently been approved for use on the NHS, and up to two more may follow within the next year. For the first time many of these new drugs offer people the chance to take a pill rather than injections, which could significantly improve quality of life for many with the condition. Iain Crosby, 47 and … Continue reading →

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HRT: Not just a women's health issue

Posted: Published on April 28th, 2014

There was a time when hormone replacement was primarily considered a women's health issue. But testosterone levels in men peak in their late teens and decrease about one percent a year, every year, once you hit 30. Your energy level, sexual function, muscle mass and bone density are all connected to the hormone. And before you see your doctor, there are some facts you need to know. MOBILE/TABLET USERS: Watch The Video Norm Dubin is active, fit, and very guarded about his age. But we do know Norm started taking testosterone under a doctor's care more than 10 years ago. "I was getting older, I was slowing down," he told WPBF 25 News. "I was losing my energy. and I was always a very active guy to begin with. And I felt it was time for me to make a change." In that one sentence, Dubin sums up what leads most men to think about hormone replacement. Boca Raton-based Dr. Mark Rosenberg, an anti-aging expert, said the No. 1 complaint his patients have before therapy is that they just don't feel well, like they used to. "It's energy level," Rosenberg said. "Many men get very fatigued. Their drive, not just … Continue reading →

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First disease-specific human embryonic stem cell line by nuclear transfer

Posted: Published on April 28th, 2014

PUBLIC RELEASE DATE: 28-Apr-2014 Contact: David McKeon dmckeon@nyscf.org 212-365-7440 New York Stem Cell Foundation NEW YORK, NY (April 28, 2014) Using somatic cell nuclear transfer, a team of scientists led by Dr. Dieter Egli at the New York Stem Cell Foundation (NYSCF) Research Institute and Dr. Mark Sauer at Columbia University Medical Center has created the first disease-specific embryonic stem cell line with two sets of chromosomes. As reported today in Nature, the scientists derived embryonic stem cells by adding the nuclei of adult skin cells to unfertilized donor oocytes using a process called somatic cell nuclear transfer (SCNT). Embryonic stem cells were created from one adult donor with type 1 diabetes and a healthy control. In 2011, the team reported creating the first embryonic cell line from human skin using nuclear transfer when they made stem cells and insulin-producing beta cells from patients with type 1 diabetes. However, those stem cells were triploid, meaning they had three sets of chromosomes, and therefore could not be used for new therapies. The investigators overcame the final hurdle in making personalized stem cells that can be used to develop personalized cell therapies. They demonstrated the ability to make a patient-specific embryonic stem … Continue reading →

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Students look to continue UWs role in stem cell research

Posted: Published on April 28th, 2014

Since being the site of the first place to isolate stem cells in non-human primates, the University of Wisconsin has continued to pave the way for scientific research in the field. Stem cells are a type of undifferentiated cell most commonly found in embryos and fetuses that have the ability to develop into different, more specialized cells. Norman Fost, UW Stem Cell and Regenerative Medicine Center, said scientists speculate that stem cells could be used for understanding of normal and abnormal development, testing of drugs for efficacy and safety and tissue transplants. James Thompson, director of regenerative biology at UW, first proposed the creation of human embryonic stem cells in 1998 after being a part of the first group to isolate stem cells in 1995. At the time, Thompson was the chair of the UW Health Sciences Institutional Review Board, Fost said. Two UW committees developed the first guidelines for human embryonic stem cell research, which became the basis for the current U.S. guidelines created by an Institute of Medicine committee, Fost said. According to a 2010 Harris Interactive poll, 72 percent of American adults believe that embryonic stem cell research, which uses stem cells harvested from in vitro fetuses, … Continue reading →

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Stem Cells Made From Cloning Diabetic Woman

Posted: Published on April 28th, 2014

Scientists have used cloning technology to make stem cells from a woman with Type 1 diabetes that are genetically matched to her and to her disease. They hope to someday use such cells as tailor-made transplants to treat or potentially even cure the disease, which affects millions and which now has few treatment options other than careful diet and regular use of insulin. Its the second report his month of success in using cloning technology to make human embryonic stem cells the cells that eventually create a complete human being and that scientists hope to harness to treat diseases ranging from diabetes to Parkinsons and injuries that cause paralysis or organ damage. I think this is going to become reality, Dr. Dieter Egli of the New York Stem Cell Foundation, whose report is published in the journal Nature on Monday, told reporters. It may be a bit in the future but it is going to happen. The technique they use is called somatic cell nuclear transfer the same method used to make Dolly, the sheep who was the first mammal to be cloned, in 1996. Scientists remove the nucleus from a normal cell, clear the nucleus from a human egg … Continue reading →

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Stem Cells from a Diabetes Patient

Posted: Published on April 28th, 2014

Researchers hope stem cells could one day treat chronic conditions like diabetes and Parkinsons disease. Healthy bloom: Insulin, shown in red, is being produced by cells that started as embryonic stem cells derived from a patient with type 1 diabetes. A series of breakthroughs in cloning technology over the last year and a half are stoking hopes that cells could be used as treatments for patients with chronic, debilitating diseases such as diabetes and Parkinsons. In January 2013, researchers at the Oregon Health and Science University reported that they had successfully created embryonic stem cells from a human embryo formed when the nucleus of one persons cell was transferred into another persons egg that had its original nucleus removed (see Human Embryonic Stem Cells Cloned). That was the first time stem cells had been made from such a cloned embryo, and the advance provides a potential route by which scientists could create various kinds of replacement cells based on a patients own genome. Many other research teams are pursuing another method of creating stem cells from a patients own cells, but some believe cells made with the cloning technique could be more likely to develop into a wide variety of … Continue reading →

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