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Genetic alterations in shared biological pathways as major risk factor for ASD

Posted: Published on April 25th, 2014

PUBLIC RELEASE DATE: 24-Apr-2014 Contact: Sid Dinsay sid.dinsay@mountsinai.org 212-241-9200 The Mount Sinai Hospital / Mount Sinai School of Medicine A substantial proportion of risk for developing autism spectrum disorders (ASD), resides in genes that are part of specific, interconnected biological pathways, according to researchers from the Icahn School of Medicine at Mount Sinai, who conducted a broad study of almost 2,500 families in the United States and throughout the world. The study, titled "Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders," was first published online in the American Journal of Human Genetics on April 24. ASD affects about one percent of the population in the United States and is characterized by impairments in social interaction and communication, as well as by repetitive and restricted behaviors. ASD ranges from mild to severe levels of impairment, with cognitive function among individuals from above average to intellectual disability. Previously, ASD has been shown to be highly inheritable, and genomic studies have revealed that that there are various sources of risk for ASD, including large abnormalities in whole chromosomes, deletions or duplications in sections of DNA called copy number variants (CNVs), and even changes of single nucleotides (SNVs) within a gene; … Continue reading →

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Stem Cell Therapy | bone marrow concentrate for osteoarthritis – Video

Posted: Published on April 25th, 2014

Stem Cell Therapy | bone marrow concentrate for osteoarthritis http://www.arthritistreatmentcenter.com In the next video I'll report on another study showing the effectiveness of stem cells in the treatment of osteoarthritis... New Study Shows Positive... By: Nathan Wei … Continue reading →

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Stemcell therapy 'adversely effected' 2025% of patients

Posted: Published on April 25th, 2014

Stamina risks range from nausea to cancer, prosecutors say (ANSA) - Turin, April 24 - Between 20% and 25% of Italian patients treated with a recently discredited stem-cell therapy called Stamina experienced "adverse effects", medical consultants said in a report submitted to prosecutors in Turin on Thursday. Such effects, said the report, had not been reported to health officials. Earlier Thursday, Turin investigators submitted a report that said risks of the treatment range from nausea to cancer. Prosecutors concluded a probe Wednesday of 20 suspects involved in the Stamina treatment, including Davide Vannoni, founder of the Stamina Foundation, who may face indictment. Charges could include criminal association to commit aggravated fraud and administration of dangerous drugs, according to prosecutors whose probe examined the treatment of slightly more than 100 patients. Another 37 donors of stem cells used in the controversial treatment, rejected by the health ministry, were examined during the investigation. According to prosecutors, Vannoni and other suspects "pretended" that there was a "high chance" of recovery from serious illness if patients agreed to the Stamina treatment. Earlier this month, hospitals in Italy that used the discredited stem-cell treatment announced they had suspended the program. That followed announcements last fall … Continue reading →

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Nanomedicine – Video

Posted: Published on April 25th, 2014

Nanomedicine None-- Created using PowToon -- Free sign up at http://www.powtoon.com/ . Make your own animated videos and animated presentations for free. PowToon is a free tool that allows you to develop... By: Stephanie Kramer … Continue reading →

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Michigan man among the first in U.S. to get a 'bionic eye'

Posted: Published on April 25th, 2014

ANN ARBOR, Mich. -- A degenerative eye disease slowly robbed Roger Pontz of his vision. Diagnosed with retinitis pigmentosa as a teenager, Pontz has been almost completely blind for years. Now, thanks to a high-tech procedure that involved the surgical implantation of a "bionic eye," he has regained enough of his eyesight to catch small glimpses of his wife, grandson and cat. "It's awesome. It's exciting -- seeing something new every day," Pontz said during a recent appointment at the University of Michigan Kellogg Eye Center. The 55-year-old former competitive weightlifter and factory worker is one of four people in the U.S. to receive an artificial retina since the Food and Drug Administration signed off on its use last year. The facility in Ann Arbor has been the site of all four such surgeries since FDA approval. A fifth is scheduled for next month. Retinitis pigmentosa is an inherited disease that causes slow but progressive vision loss due to a gradual loss of the light-sensitive retinal cells called rods and cones. Patients experience loss of side vision and night vision, then central vision, which can result in near blindness. Not all of the 100,000 or so people in the U.S. … Continue reading →

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Stem Cell Transplant Patients | Fungal Infections | Fungal …

Posted: Published on April 25th, 2014

As a stem cell transplant patient, you have new opportunities for a healthy and full life. Stem cell transplants [PDF - 3 pages] have many benefits, but they also have risks. Because stem cell transplants destroy and rebuild your immune system, they increase your risk for fungal infections. There are two main types of stem cell transplants: There are different reasons for receiving either type of transplant. You and your healthcare provider will discuss your options and choose the treatment thats best for you. A transplant using stem cells from a donor increases your risk for fungal infection more than a transplant that uses stem cells from your own body. If your stem cells come from another person, you will need to take anti-rejection medication. This medication weakens your immune system.1 Chemotherapy and radiation lower your white blood cell count. As you recover from your transplant, your white blood cell count can become very low, also known as neutropenia [PDF - 4 pages]. During this time, your body will have trouble fighting infections, including fungal infections.2 Graft-versus-host disease (GVHD). If you receive stem cells from a donor, the transplanted stem cells may attack your body. This is known as graft-versus-host … Continue reading →

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Blood cancer patients have local option for marrow transplants

Posted: Published on April 25th, 2014

by JIM BERGAMO / KVUE News and editor Rob Diaz kvue.com Posted on April 22, 2014 at 5:14 PM Updated Tuesday, Apr 22 at 7:00 PM AUSTIN -- Doctors at St. Davids South AustinMedical Center recently performed the first adult hematopoieticstem cell transplant, which is a type of blood and marrowtransplant. Prior to the new comprehensive blood cancer center,patients had to leave Austin to get the treatment they needed. Earlier this year, Nancy Guerra enjoyed some down time at her Northwest Austin home, putting together an electronic puzzle. But her own health became far more puzzling than anything she could piece together on her I-Pad. She suffered from multiple myeloma and had intense chemotherapy treatments in preparation for a more important procedure. Doing the chemotherapy is really good, said Guerra. It puts me in remission, but Im not going to stay in remission anywhere near as long as I will when I have a bone marrow transplant. But like other patients with bone cancer disorders where to go to get that blood marrow is the key question. Austin is reaching a critical mass size, said David Huffstutler, President and Chief Executive Officer, St. Davids HealthCare. While we already have a … Continue reading →

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More Media Coverage for MediVet Stem Cell Therapy at Newman Veterinary Centers – Central Florida – Video

Posted: Published on April 25th, 2014

More Media Coverage for MediVet Stem Cell Therapy at Newman Veterinary Centers - Central Florida We are proud to offer this amazing procedure at Newman Veterinary Centers. Stem cell therapy can help pets with arthritis, hip dysplasia and many other degenerative conditions. Learn more at... By: Newman Veterinary Centers … Continue reading →

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Stem Cell Therapy | bone marrow concentrate for osteoarthritis – Video

Posted: Published on April 25th, 2014

Stem Cell Therapy | bone marrow concentrate for osteoarthritis http://www.arthritistreatmentcenter.com In the next video I'll report on another study showing the effectiveness of stem cells in the treatment of osteoarthritis... New Study Shows Positive... By: Nathan Wei … Continue reading →

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Neck/knee/shoulder/wrist pain 7 months after stem cell therapy by Dr Harry Adelson – Video

Posted: Published on April 25th, 2014

Neck/knee/shoulder/wrist pain 7 months after stem cell therapy by Dr Harry Adelson Neck/knee/shoulder/wrist pain 7 months after stem cell therapy by Dr Harry Adelson http://www.docereclinics.com. By: Harry Adelson, N.D. … Continue reading →

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