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Japan stem cell scientist stands by phoney research

Posted: Published on April 10th, 2014

TOKYO: A young female scientist accused of fabricating data made a tearful apology live on Japanese television yesterday for mistakes in her research, but insisted her ground-breaking conclusions on stem cells were accurate. Haruko Obokata, 30, blamed her youth and inexperience for errors in her methodology, but said she had managed to create the building-block cells capable of growing into the specialised cells of the brain, liver, heart or kidneys. I apologise with my whole heart to my co-authors and many others for causing trouble because of my insufficient efforts, ill-preparedness and unskilfulness, a visibly shaken Obokata told a press conference. To many people there may be too many unbelievable mistakes, but that does not affect the conclusion, she said. Obokata was feted as a modern-day Marie Curie after unveiling research that showed a simple way to re-programme adult cells to become a kind of stem cell. So-called Stimulus-Triggered Acquisition of Pluripotency (STAP) cells were hailed as a breakthrough that could provide a ready supply of the base material for much-needed transplant tissue at minimal cost. Campaigners said it represented a leap forward in the fight against degenerative diseases. Her profile a young woman in a world dominated by middle-aged … Continue reading →

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Maligned stem cell researcher insists results valid

Posted: Published on April 10th, 2014

Elaine Kurtenbach, The Associated Press Published Wednesday, April 9, 2014 7:55AM EDT TOKYO -- The Japanese scientist accused of falsifying data in a widely heralded stem-cell research paper said Wednesday the results are valid despite mistakes in presentation of the results. Haruko Obokata, 30, struggled to maintain her composure during a televised news conference packed with hundreds of reporters, but insisted she did not tamper with the data to fabricate results. She said she did not agree with retracting the research that appeared in the scientific journal Nature. The phenomenon of ordinary cells transforming into stem cells under the influence of external stimulus was "confirmed many times for a fact," Obokata said at the press conference in the western city of Osaka. She said she could replicate her results again if allowed back into the lab to do so. She has contested allegations of research malpractice made by a panel of scientists at the government-funded Riken Center for Development Biology, where she is employed. Obokata said Riken had advised her not to speak publicly about the controversy. The event Wednesday, which lasted for over two hours, was her first public appearance in weeks and was made against doctors' orders after … Continue reading →

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Scientist denies faking stem cell paper

Posted: Published on April 10th, 2014

ByElaine Kurtenbach The Japanese scientist accused of falsifying data in a widely heralded stem cell research paper says the results are valid despite mistakes in their presentation. Haruko Obokata, 30, struggled to maintain her composure during a televised news conference packed with hundreds of reporters, but insisted she did not tamper with the data to fabricate results. She said she did not agree with retracting the research that appeared in the scientific journal Nature. The phenomenon of ordinary cells transforming into stem cells under the influence of external stimulus was "confirmed many times for a fact", Obokata said at the press conference in the western city of Osaka. She said she could replicate her results again if allowed back into the lab to do so. She has contested allegations of research malpractice made by a panel of scientists at the government-funded Riken Center for Development Biology, where she is employed. Obokata said Riken had advised her not to speak publicly about the controversy. The event Wednesday, which lasted for over two hours, was her first public appearance in weeks and was made against doctors' orders after seeking hospital treatment Monday. "I wasn't able to sleep well and was feeling worse … Continue reading →

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Mahendra Rao Joins The New York Stem Cell Foundation Research Institute

Posted: Published on April 10th, 2014

Contact Information Available for logged-in reporters only Newswise NEW YORK, NY (April 9, 2014) Dr. Mahendra Rao, who has directed the Center for Regenerative Medicine at the National Institutes of Health (NIH CRM) since 2010, will join The New York Stem Cell Foundation (NYSCF) Research Institute as its Vice President for Regenerative Medicine, a newly created position, Susan Solomon, NYSCF Chief Executive Officer, announced today. Dr. Rao, who holds an MD degree and a PhD in developmental neurobiology, is one of the nations most prominent stem cell scientists. He has over twenty years of experience in all aspects of the stem cell field including government, academia, and business. Before joining the NIH, Dr. Rao spent six years as the vice president of Regenerative Medicine at Life Technologies, Inc. (now Thermo Fisher Scientific) after serving as the chief of Neurosciences at the National Institute on Aging and co-founding Q Therapeutics, a neural stem cell company based in Utah. Dr. Rao is tenured at the University of Utah School of Medicine in both Neurobiology and Anatomy and has over twenty submitted and ten issued patents. Dr. Raos expertise in translational research, academia, and industry make him a valuable asset in our mission … Continue reading →

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Study by prominent Brigham scientists retracted due to compromised data

Posted: Published on April 10th, 2014

A Brigham and Womens Hospital stem cell study, which raised the possibility that the human heart could repair itself, has been retracted after an internal investigation showed the researchers used compromised data. The retraction comes just a week after a Japanese scientist was accused of fabricating data in a major stem cell paper that was led by a different Brigham scientist. The authors of the retracted paper claimed they had found evidence that heart muscle can regenerate at a higher rate than previously thought. The work was part of a broad effort to discover the bodys natural regenerative abilities and harness them to create therapies that could repair damaged or diseased hearts. The paper, published in 2012 in the journal Circulation, was withdrawn Tuesday by the journals publisher, the American Heart Association. An ongoing institutional review by Harvard Medical School and Brigham and Womens Hospital has determined that the data are sufficiently compromised that a retraction is warranted, the journal said. This retraction is highly significant. In my 30 years in cardiovascular science I cannot recall a paper of similar prominence being retracted from Circulation, Dr. Charles Murry, codirector of the Institute for Stem Cell and Regenerative Medicine at the … Continue reading →

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FDA Approves CardioCell's Phase 2A Trial For CHF Stem Cell …

Posted: Published on April 10th, 2014

By Estel Grace Masangkay CardioCell LLC announced that it has received FDA approval for its investigational new drug (IND) application for a U.S.-based Phase IIA clinical study evaluating its allogeneic stem-cell therapy for patients with chronic heart failure (CHF). Dr. Sergey Sikora, CardioCells president and CEO, said, With the FDAs IND approval, CardioCell is pleased to proceed with a Phase 2a CHF clinical trial based on the safety data reported in previous clinical trials using our unique, hypoxically grown stem cells. At the studys conclusion we will understand if our therapy produces signs of improvement in a population of patients with dilated CHF, a condition largely unaddressed by current therapies. Dilated CHF is characterized by a viable but non-functioning myocardium in which cardiomyocytes are alive but are not contracting as they should. We hope that unique properties of our itMSCs will transition patients cardiomyocytes from viable to functioning, eventually improving or restoring heart function. The company has developed an ischemic tolerant mesenchymal stem cells (itMSC) treatment for the type of dilated CHF that is not related to coronary artery disease. The treatment could potentially apply to about 35 percent of CHF patients. Only CardioCells CHF therapies feature itMSCs, exclusively licensed … Continue reading →

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Take 1 – after second stem cell treatment – 9 april 2014 – Video

Posted: Published on April 10th, 2014

Take 1 - after second stem cell treatment - 9 april 2014 My name is Carole St-Laurent, I live in Rimouski, Quebec, Canada, I have a muscular Dystrophy(spinal muscular atrophy type 2-3) since birth, I'm now 43 years... By: Kina Diamond … Continue reading →

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Irvine Stem Cell Treatment Center: Public Seminar on Adipose Derived Stem Cells

Posted: Published on April 10th, 2014

Irvine, California (PRWEB) April 09, 2014 The Irvine Stem Cell Treatment Center, located in Irvine, California, announces a free public seminar on the use of stem cells for various degenerative and inflammatory conditions. They will be provided by Dr. Thomas A. Gionis, Surgeon-in-Chief. The seminar will be held on April 13. On April 13 and will be held at 3500 Barranca Parkway, Suite 315, Irvine, CA 92606 at 2 p.m. At the Irvine Stem Cell Treatment Center, utilizing investigational protocols, adult adipose derived stem cells (ADSCs) can be deployed to improve patients quality of life with a number of degenerative conditions and diseases. ADSCs are taken from the patients own adipose (fat) tissue (also called stromal vascular fraction (SVF). Adipose tissue is exceptionally abundant in ADSCs. The adipose tissue is obtained from the patient during a 15 minute mini-liposuction performed under local anesthesia in the doctors office. SVF is a protein-rich solution containing mononuclear cell lines (predominantly autologous mesenchymal stem cells), macrophage cells, endothelial cells, red blood cells, and important Growth Factors that facilitate the stem cell process and promote their activity. ADSCs are the body's natural healing cells - they are recruited by chemical signals emitted by damaged tissues … Continue reading →

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National Stem Cell Coordinating Centre Launched

Posted: Published on April 10th, 2014

KUALA LUMPUR, April 10 (Bernama) - The Ministry of Health finally realised its wish to have a National Stem Cell Coordinating Centre (NSCCC) which was launched Thursday. Director of Medical Development Division, Datuk Dr Azmi Shapie said the NSCCC was built at a mere cost of RM50,000 using the expertise from its own staff. "I hope the existence of the NSCCC can benefit patients in dire need of stem cell treatment," he told reporters after launching the NSCCC at the National Blood Centre here, on behalf of the director-general of Health, Datuk Dr Noor Hisham Abdullah. In a statement distributed to reporters, Dr Noor Hisham said stem cells could only be obtained from blood vessels, bone marrow or umbilical cord blood to produce different types of blood components needed to treat patients. It said all Malaysians aged 18 to 50 years who are healthy and free from infectious diseases and chronic diseases are encouraged to register as cell donors. Among the diseases that may be treated with stem cell blood transplant are leukemia, lymphoma, thalassemia and aplastic anemia. Statistics (from 2006 to March 31) show that 22,933 Malaysians or 0.08 per cent of the total population registered as stem cell … Continue reading →

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Gloria Arroyos stem cell therapy doc blamed for cancer patient's death

Posted: Published on April 10th, 2014

A doctor offering stem cell therapy may face charges for the death of a cancer patient who allegedly underwent treatment similar to that administered to former president and incumbent Pampanga Rep. Gloria Macapagal-Arroyo. This was after it was found out that she is not a licensed doctor in the Philippines. A report on GMA News TV's "News To Go" on Wednesday said a complaint has been filed against Dr. Antonia Carandang-Park at the National Bureau of Investigation (NBI) by Bernard Tan, who claims that his daughter, Kate, died after going through the said alternative treatment.Cancer patient Kate Tan received stem cell therapy from Dr. Antonia Carandang-Park, Gloria Arroyo's doctor. Park owns the Tagaytay-based Green & Young Health and Wellness Center where Arroyoburdened by persistent trouble with her cervical spinesought treatment in 2012. In an interview with GMA News, Tan said his daughter, who had Hodgkin's lymphoma (a type of cancer of the blood), was given "the same treatment that [Park] did with Gloria," which included "juicing diet, vegetable diet... acupuncture coffee enema, at 'yun na nga, stem cell." Stem cell therapy introduces new adult stem cells into damaged tissue in order to treat disease or injury. "Ang sabi niya, 'Give … Continue reading →

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