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Breakthrough therapy allows 4 paraplegic men to voluntarily move their legs

Posted: Published on April 8th, 2014

PUBLIC RELEASE DATE: 8-Apr-2014 Contact: Stuart Wolpert swolpert@support.ucla.edu 310-206-0511 University of California - Los Angeles Four young men who have been paralyzed for years achieved groundbreaking progress moving their legs as a result of epidural electrical stimulation of the spinal cord, an international team of life scientists reports today in the medical journal Brain. The study, conducted by researchers from the University of Louisville, UCLA and the Pavlov Institute of Physiology, was funded in part by the Christopher and Dana Reeve Foundation and the National Institutes of Health. All four participants were classified as suffering from chronic, motor complete spinal cord injuries and were unable to move their lower extremities prior to the implantation of an epidural stimulator. The stimulator delivers a continuous electrical current to the participants' lower spinal cords, mimicking signals the brain normally transmits to initiate movement. The research builds on an initial study, published in May 2011 in the journal The Lancet, that evaluated the effects of epidural stimulation in the first participant, Rob Summers of Portland, Ore., who recovered a number of motor functions as a result of the intervention. Now, three years later, the key findings documented in Brain detail the impact of epidural … Continue reading →

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Spinal Stimulation Helps Four Patients with Paraplegia Regain Voluntary Movement

Posted: Published on April 8th, 2014

Contact Information Available for logged-in reporters only Newswise Four people with paraplegia are able to voluntarily move previously paralyzed muscles as a result of a novel therapy that involves electrical stimulation of the spinal cord, according to a study funded in part by the National Institutes of Health and the Christopher & Dana Reeve Foundation. The participants, each of whom had been paralyzed for more than two years, were able to voluntarily flex their toes, ankles, and knees while the stimulator was active, and the movements were enhanced over time when combined with physical rehabilitation. Researchers involved in the study say the therapy has the potential to change the prognosis of people with paralysis even years after injury. When we first learned that a patient had regained voluntary control as a result of spinal stimulation, we were cautiously optimistic, said Roderic Pettigrew, Ph.D., M.D., director of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) at NIH, which provided support for the study. Now that spinal stimulation has been successful in 4 out of 4 patients, there is evidence to suggest that a large cohort of individuals, previously with little realistic hope of any meaningful recovery from spinal cord injury, … Continue reading →

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Animal Testing: Parkinson's Charity Condemned For Funding 'Profoundly Disturbing' Experiments

Posted: Published on April 8th, 2014

British charity The Cure Parkinson's Trust has been condemned for funding "profoundly disturbing" experiments in which monkeys have their brains damaged to mimic symptoms of Parkinson's disease. The suffering induced was said to be "severe" under the rating system used by the Home Office to assess animal tests. In one case, the monkeys had already been subjected to similar tests in previous studies. The research, published in 2011 and 2012, was conducted in Canada but was supported by the UK charity. Both teams of scientists were testing ways to reduce the side effects of drug treatment for Parkinson's. The experiments involved dosing marmoset monkeys with the toxic chemical MPTP to damage their brains and induce the symptoms. High doses of the drug L-Dopa were then administered producing severe side effects including dyskinesia, or uncontrolled movement and psychosis. The scientific papers about the experiments cite Cure Parkinson's Trust as a co-funder. Andrew Tyler, director of the animal rights group Animal Aid, said: "It is clear that the vast majority of the British public do not want their money being used to fund profoundly disturbing experiments on animals of the sort co-funded by the Cure Parkinson's Trust. Read more: Animal Testing: Parkinson's … Continue reading →

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Mental-health treatment void in Colo.

Posted: Published on April 8th, 2014

Enlarge photo Joe Mahoney/ I-News at Rocky Mountain PBS Alex Meredith, 29, sorts clothes hangers at his part-time job at Arc Thrift Store in Lakewood. Meredith was diagnosed with autism when he was very young. He also displayed symptoms of mental illness obsessive-compulsive disorder, anxiety, psychosis and depression. Seeking treatment for these conditions means navigating a fragmented system with funding quirks and huge gaps in care. Joe Mahoney/ I-News at Rocky Mountain PBS Alex Meredith, 29, sorts clothes hangers at his part-time job at Arc Thrift Store in Lakewood. Meredith was diagnosed with autism when he was very young. He also displayed symptoms of mental illness obsessive-compulsive disorder, anxiety, psychosis and depression. Seeking treatment for these conditions means navigating a fragmented system with funding quirks and huge gaps in care. A raised red oval, a couple of inches in diameter, sits at the top of Alex Merediths forehead. It is the physical mark of a besieged mind. Meredith, who is 29, started bashing himself in the head when he was in his teens. Now, his parents can see it coming. A tranquil moment of drawing at the kitchen table cedes to Merediths high-pitched squeal, his wrists colliding. Once he starts … Continue reading →

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HRT no longer a dirty term

Posted: Published on April 8th, 2014

It is hard to understand a woman who had a double mastectomy more than 10 years ago and hear her sing the praises of estrogen. This important female hormone, whose production declines with age, is linked to breast cancer. Its especially shocking to know that this particular woman, Dr. Melanie Bone, specializes in womens health issues and talks herself silly trying to remove the fear factor from her patients. Bone, who is now affiliated with JFK Medical Center in Atlantis, recently moved into the former office of Island Medical Care. She considers educating women on hormone replacement a top priority. A big part of what I do is to convince people they shouldnt be so scared of estrogen, she said. I am a big fan of estrogen. Many women are scared of hormone-replacement therapy. Thats especially true for older women, who recall all too clearly the loud debate that ensued about whether so-called HRT helped or harmed post-menopausal women. Today, HRT is no longer a dirty term. But it comes with a huge warning sign on the U.S. governments website, MedlinePlus: Hormone-replacement therapy may increase the risk of heart attack, stroke, breast cancer, and blood clots in the lungs and … Continue reading →

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Ertel Medicine now offering genetic testing

Posted: Published on April 8th, 2014

Print Create a hardcopy of this page Font Size: Default font size Larger font size National Public Health Week now under way Observation recognizes strides made, changes needed in US health system Posted: Monday, April 7, 2014 11:07 am Ertel Medicine now offering genetic testing Ertel Medicine and Pediatrics is now offering special genetic testing called pharmocogenetic testing. The test helps the medical provideradminister the most accurate treatment based on each patients unique science. Since everyone processes medications differently, this may be the key to help my patientsget to the sweet spot sooner, Dr. Larry Ertel said in a news release. Whether it is Plavix (a heart medicine) which is known to havesevere adverse reactions if the dose is too high or just a common reflux medicine or even anti-depressants I will be able to see how a patient metabolizes medicine and adjust accordingly. An online service is needed to view this article in its entirety. You need an online service to view this article in its entirety. With this digital membership, you not only get unlimited access to The Winchester Sun website but to the e-edition as well. With this digital membership, you get unlimited access to websites of … Continue reading →

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Proove Biosciences Research Recognized and Presented at the American Society of Interventional Pain Physicians 16th …

Posted: Published on April 8th, 2014

Irvine, CA (PRWEB) April 07, 2014 Proove Biosciences, the leader in Personalized Pain Medicine testing services, exhibited and presented research from three studies at the American Society of Interventional Pain Physicians' (ASIPP) 16th annual meeting in New Orleans. The event took place at the Hilton New Orleans Riverside hotel, this weekend, April 4-6. Proove submitted abstracts on three IRB-approved clinical studies to ASIPP for presentation at the annual meeting. Out of many abstracts submitted by various researchers, ASIPP only accepted 20 studies for presentation and publication. All three Proove study abstracts were accepted for poster presentation, and one of Proove's study abstracts was selected in the "Top 5 Posters" presented before the general session on Saturday afternoon. Specifically, the company plans to present: Predictive Risk of Injury Complications Enduring Over one Year Using Genetic Predisposition (P.R.I.C.E.) Study, MED Scale to Predict Hydrocodone Efficacy versus the Pain VAS Score Study, and Perception of Analgesia in Narcotic Users with Chronic Pain: A Multi-Center Cross-Sectional Study Comparing Genotype to Pain VAS (P.A.I.N.) Study. On Saturday afternoon, Proove's Medical Director for Pain and Addiction, Daniel Schwarz, MD, MROC presented information on Prooves P.R.I.C.E. study during the "Top 5 Posters" session. The PRICE Study demonstrates … Continue reading →

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Cleft palate discovery in dogs to aid in understanding human birth defects

Posted: Published on April 8th, 2014

UC Davis School of Veterinary Medicine researchers have identified the genetic mutation responsible for a form of cleft palate in the dog breed Nova Scotia Duck Tolling Retrievers. They hope that the discovery, which provides the first dog model for the craniofacial defect, will lead to a better understanding of cleft palate in humans. Although cleft palate is one of the most common birth defects in children, affecting approximately one in 1,500 live human births in the United States, it is not completely understood. The findings appear this week online in the journal PLOS Genetics and are available at https://tinyurl.com/knr8wb3. "This discovery provides novel insight into the genetic cause of a form of cleft palate through the use of a less conventional animal model," said Professor Danika Bannasch, a veterinary geneticist who led the study. "It also demonstrates that dogs have multiple genetic causes of cleft palate that we anticipate will aid in the identification of additional candidate genes relevant to human cleft palate." Bannasch, who holds the Maxine Adler endowed chair in genetics, explains that common breeding practices have made the dog a unique animal model to help understand the genetic basis of naturally occurring birth defects. By conducting … Continue reading →

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VIDEO | Ateneo graduate dies after undergoing stem cell therapy

Posted: Published on April 8th, 2014

By: Ina Zara, News5 April 7, 2014 9:05 PM Contributed file photo of Katherine Grace Tan. InterAksyon.com The online news portal of TV5 MANILA, Philippines A cum laude graduate from the Ateneo de Manila University, who was suffering from Hodgkin's lymphoma, died last year after undergoing embryonic stem cell therapy that was allegedly administered by Antonia Park, the alternative medicine doctor of former President Gloria Macapagal-Arroyo. Bernard Tan claimed that Park had promised that within three months, his 23-year-old daughter, Katherine Grace Tan, would be cured of her disease, which according to the doctor was not cancer but just hormonal imbalance. But after undergoing treatment and strictly following a juice diet, Katherine got weaker and died. Earlier this month, it was reported that Park, of the Green & Young Health & Wellness Center,admitted that she wasnt licensed to practice in the Philippines. Records from the theProfessional Regulatory Commission as of August 2013 showed that Park was not on the list of physicians authorized to practice medicine in the country. Link: VIDEO | Ateneo graduate dies after undergoing stem cell therapy … Continue reading →

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Transplantation Cell Therapy Offers Hope to Stroke Patients

Posted: Published on April 8th, 2014

Contact Information Available for logged-in reporters only Newswise SAN FRANCISCO (April 7, 2014) The devastating effects of stroke have long led physicians to conclude that lost brain function is irreversible. Today during the 82nd Annual Scientific Meeting of the American Association of Neurological Surgeons (AANS), researchers presented the results of a groundbreaking study that offers new hope to stroke patients. In the first North American trial of its kind, researchers conducted intraparenchymal transplantation of bone marrow-derived cell therapy in chronic stroke patients. Titled A Novel Phase 1/2A Study of Intraparenchymal Transplantation of Human Modified Bone Marrow Derived Cells in Patients with Stable Ischemic Stroke, the study tested the feasibility of administering escalated doses of stromal cells. Numerous preclinical animal stroke studies showing the benefit of stem cell transplantation led to the initiation of this clinical trial. The study was led by Gary K. Steinberg, MD, PhD, FAANS: Although this was primarily a safety study, we found a significant recovery of neurologic function in patients overall at six months that is sustained at one year. Two of the 18 transplanted patients showed remarkable improvement. Transplanted patients continued to recover substantial neurologic function two years or more following their stroke, said Dr. … Continue reading →

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