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UConn looking for MS patients for on-going study

Posted: Published on March 26th, 2014

Related Content FARMINGTON, Conn. (WTNH) There is promising research for patients with multiple sclerosis. The on-going study at UConn Health Center is looking for more people with MS to sign up. Unlocking the cause for auto-immune diseases like Mutiple Sclerosis has proved challenging. But millions of dollars of research funding from the National MS Society has led UConn researchers to discover a strong link that could affect treatment. Its in the UConn Health Center laboratory, where research scientist Dr. Robert Clark and his team are studying the role of gastro-intestinal bacteria in auto-immune diseases like Multiple Sclerosis, which attacks the central nervous system. Can the bacteria in the GI Tract affect diseases like this? said Clark. In a small study comparing blood samples of MS patients with a control group, the lead investigator found a link. This is a group of typical bacteria that we believe that are in the gastrointestinal tract, said Clark. While the bacteria was common to both the levels of a certain molecule it secretes were not. In 17 out of 17 MS patients, all of them had very low levels of this molecule, said Clark. In animal studies they found even more significant findings. View … Continue reading

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Medical marijuana eases some MS symptoms, neurologists report

Posted: Published on March 26th, 2014

There is strong evidence that medical marijuana pills may reduce symptoms of spasticity and pain reported by multiple sclerosis patients, but little proof that smoking pot offers the same benefit, according to new alternative treatment guidelines released by the American Academy of Neurology. The guidelines on complementary and alternative medicine, or CAM, treatments for MS were published Monday in the journal Neurology and are among the first from a national medical organization to suggest that doctors might offer cannabis treatment to patients. Though advocates of medical marijuana use said the guidelines appeared to be part of a recent national trend in which doctors were seriously evaluating the use of cannabis, they argued that the federal government had stymied marijuana research. "The reason there's no evidence on inhaled cannabis is because it's very difficult to study," said Dr. Donald Abrams, a professor of clinical medicine at the University of California San Francisco and a marijuana researcher who was not involved in the guideline study. "The government really restricts studies of the plant." A panel of AAN researchers based their guidelines on a review of 115 clinical studies that examined a variety of alternative MS treatments, including the use of ginkgo biloba, … Continue reading

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Medical Marijuana Pills May Ease Some MS Symptoms: Review

Posted: Published on March 26th, 2014

By Maureen Salamon HealthDay Reporter MONDAY, March 24, 2014 (HealthDay News) -- Medical marijuana pills and sprays might ease the symptoms of multiple sclerosis, but most other alternative therapies do little to lessen the pain and muscle rigidity that often accompanies the disease, according to new guidelines. To reach that conclusion, an expert panel from the American Academy of Neurology reviewed more than 40 years of research on alternative medicine treatments for multiple sclerosis (MS). In addition to the recommendations about medical marijuana use, the nine experts also found that ginkgo biloba might help with the fatigue of MS and reflexology may ease MS symptoms such as tingling, numbness and other unusual skin sensations. Bee sting therapy and omega-3 fatty acids, however, offer weak evidence supporting their use. "It's a very common practice in the MS patient population to try alternative therapies," said the author of the guidelines, Dr. Vijayshree Yadav, clinical director of Oregon Health & Science University's MS Center, in Portland. "The problem is there was never an evidence-based recommendation for MS patients or those taking care of patients," Yadav said. "This is a first step to educate each audience." The guidelines are published in the March 25 … Continue reading

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Marijuana pills and sprays ease MS symptoms

Posted: Published on March 26th, 2014

Current ratings for: Marijuana pills and sprays ease MS symptoms Public / Patient: 4.5 8 ratings Health Professionals: 1.5 4 ratings Multiple sclerosis is characterized by disrupted communication between the brain and the body, resulting in symptoms ranging from blurred vision to muscle weakness and pain. There is no cure for the condition, and therapies have proven difficult, as many have serious side effects. But now, relief may come in the form of a medical marijuana pill. This is according to a new guideline released from the American Academy of Neurology and published in its journal Neurology. The guideline investigated complementary or alternative medicine therapies (CAM) for multiple sclerosis (MS). These are unconventional therapies used alongside or instead of doctor-recommended therapies. Medical News Today recently wrote a spotlight feature focusing on symptoms and treatments for the condition to coincide with National Multiple Sclerosis Awareness Month in March. In that feature, Arney Rosenblat, associate vice president of the National Multiple Sclerosis Society, told us that though there are currently 10 disease-modifying therapies approved by the Food and Drug Administration (FDA) for MS, "there is deep unmet need for additional therapies, especially to treat progressive forms of disease for which there are … Continue reading

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Unravelling Nerve-Cell Death in Rare Children's Disease

Posted: Published on March 26th, 2014

Contact Information Available for logged-in reporters only Newswise LA JOLLA, Calif., March 25, 2014 A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute (Sanford-Burnham), recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died. A-T is a hereditary condition that begins early in childhood, and causes a gradual loss of certain nerve cells in the cerebellum of the brain. A-T occurs in about 1 in 40,000 births, with symptoms including severe loss of muscle control, dilated small blood vessels, repeated infections in the sinus and lungs, and it frequently leads to cancers such as lymphoma or leukemia. Today, thanks to improved treatment of infections and cancer, many patients live into their 30s or longer. His study, with Nobuki Nakanishi, Ph.D., associate professor in Sanford-Burnhams Degenerative Disease Program, was published March 25 in The Journal of Neuroscience. The researchers used genetically engineered mice to show that myoctye-enhancer factor 2D (MEF2D), a transcription factor that turns on specific genes involved in cell survival, is activated after binding to a protein known as A-T mutated … Continue reading

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Friedreichs Ataxia: Emily Penn hits the road in The Ride to Cure FA

Posted: Published on March 26th, 2014

Emily Penn is on a mission. Shes training for the 4th annual Ride to Cure Friedreichs Ataxia. Shes always been active. When she 15 years old and running track she was diagnosed with tendonitis and that same doctor also noticed Emily had an unusual walk. She went to a specialist for an MRI and genetic blood test then received the life changing diagnosis. My mom received a phone call a few weeks later from the doctors saying the results came in and it was Friedreichs Ataxia, Emily recalled. It was a complete blow to my family. Six short years later, shes 21 and now uses a walker to help her get around. Balance and coordination usually go first. Speech is also impacted as the central nervous system breaks down. Its not the future she envisioned. It was really scary and really dark that I would be in a wheelchair in a matter of years and die prematurely of a heart condition, Emily said. I mean, how do you move on from that? She moved on by chipping in and raising awareness and research money by pedaling in The Ride to Cure FA. She gave and received at the same time. … Continue reading

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Burney earns certification in veterinary practice

Posted: Published on March 26th, 2014

March 24, 2014 Burney earns certification in veterinary practice Anonymous Special to The Sun The Edmond Sun Mon Mar 24, 2014, 06:47 PM CDT EDMOND Beth Burney recently earned the distinction of Certified Veterinary Practice Manager by successfully passing the certification exam offered by the Veterinary Hospital Managers Association on March 11 in Edmond. VHMAs certification program measures the knowledge and experience necessary to successfully manage the ever-changing business environment of todays veterinary practices and requires a continued commitment to further improvement through continuing education. This designation is VHMAs highest professional distinction. The Veterinary Hospital Managers Association Inc. is an international professional association, created in 1981, to support individuals in veterinary practice management. Its guiding principles include the pursuit of excellence in practice management, opening channels of communication and networking among practices. More than 1,600 hospital managers, veterinarians, technicians and consultants belong to the VHMA. Its membership is international consisting of 10 percent Canadian citizens and 90 percent U.S. citizens. Members of the VHMA benefit from conferences and meetings exclusively devoted to management; newsletters on current management topics, written by managers for managers; benchmark surveys; an online Career Center; a Mentor Program; a complimentary subscription to Veterinary Economics magazine, and … Continue reading

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Stem Cells Shed Light On Bipolar Disease

Posted: Published on March 26th, 2014

Researchers have grown embryonic-like stem cells from patients with bipolar disorder and transformed them into brain cells that are already answering questions about the condition. The cells, which carry the precisely tailored genetic instructions from the patients own cells, behave differently than cells taken from people without the disorder, the researchers report. Already, we see that cells from people with bipolar disorder are different in how often they express certain genes, how they differentiate into neurons, how they communicate, and how they respond to lithium," Sue O'Shea, a stem cell specialist at the University of Michigan who led the study, said in a statement. The work, described in the journal Translational Psychiatry, helps fulfill one of the big promises of stem cells research using a patients own cells to study his or her disease. Mental illness is especially hard to study. Getting into a living persons brain is almost impossible, and scientists cant deliberately cause it in people in order to study it. Creating animals such as mice with what looks like human mental illness is imprecise at best. The University of Michigan team turned instead to what are called induced pluripotent stem cells, or iPS cells. These are ordinary … Continue reading

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Hopes high for Obama meeting with Pope Francis at Vatican

Posted: Published on March 26th, 2014

Gay marriage. Abortion. Stem cell research. Theres plenty for President Obama and Pope Francis to discuss when they meet Thursday at the Vatican. But beyond their doctrinal differences lies a mutual desire for social justice that likely will tamp down any friction in their first meeting, analysts say. Same-sex marriage and abortion might be points of contention, but the hope is that Mr. Obama and Francis can find a point of convergence on other topics, said Paul Manuel, director of the Institute for Leadership, a nonprofit that promotes the application of biblical wisdom in decision-making. Were looking at two global superpowers that have competing visions of justice, said Mr. Manuel, a political science professor at Mount St. Mary's University. Im sure the White House would like to have convergence with the Vatican. One area that might help them is the popes initiative on human trafficking. I think thats something the president would be happy to discuss. Francis this month announced his support of the National Conference of Brazilian Bishops Brotherhood Campaign, which aims to stem human slavery in Brazil. Mr. Manuel suggested that the persecution of Christians in the Middle East as another likely topic. He said the issue could … Continue reading

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Implications of Patient Genomic Sequencing at ACMG

Posted: Published on March 26th, 2014

Released: 3/25/2014 4:05 PM EDT Source Newsroom: Mayo Clinic Contact Information Available for logged-in reporters only http://newsnetwork.mayoclinic.org/discussion/implications-of-patient-genomic-sequencing-at-acmg Newswise ROCHESTER, Minn. Researchers from the Mayo Clinic Center for Individualized Medicine will present results of three different studies evaluating implications and feasibility of genome sequencing at the ACMG Annual Clinical Genetics Meeting this week in Nashville, Tenn. Presenters are available for interviews at the conference or remote interviews by telephone. To schedule an interview, please contact Sam Smith, Mayo Clinic public affairs specialist, at 507-284-5005 or newsbureau@mayo.edu. Richard Sharp, Ph.D., director of the Bioethics Program in the Mayo Clinic Center for Individualized Medicine, also will participate on Saturday, March 30, in a panel discussion entitled Duty to Recontact in the Genomics Era: Interdisciplinary Perspectives and Open Forum. Duty to Recontact addresses providers obligations to patients who have undergone previous genetic testing, given the growing complexities of genetic/genomic medicine and the potential for new findings in old tests. Dr. Sharp is an advisor to the National Institutes of Health, the Institute of Medicine and the Environmental Protection Agency. He can discuss the ethical, legal and social implications of integrating genomics technologies into patient care. The Mayo Clinic Center for Individualized Medicine presentations include: … Continue reading

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