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Stem Cell Transplant Shows "Landmark" Promise for Treatment of Degenerative Disc Disease: Mayo Clinic

Posted: Published on March 7th, 2014

Contact Information Available for logged-in reporters only Newswise March 7, 2014, Phoenix, AZ -- Stem cell transplant was viable and effective in halting or reversing degenerative disc disease of the spine, a meta-analysis of animal studies showed, in a development expected to open up research in humans. Recent developments in stem cell research have made it possible to assess its effect on intervertebral disc (IVD) height, Mayo Clinic researchers reported in a scientific poster today at the 30th Annual Meeting of the American Academy of Pain Medicine. This landmark study draws the conclusion in pre-clinical animal studies that stem cell therapy for disc degenerative disease might be a potentially effective treatment for the very common condition that affects peoples quality of life and productivity, said the senior author, Wenchun Qu, MD, PhD, of the Mayo Clinic in Rochester, Minn. Dr. Qu said not only did disc height increase, but stem cell transplant also increased disc water content and improved appropriate gene expression. These exciting developments place us in a position to prepare for translation of stem cell therapy for degenerative disc disease into clinical trials, he said. The increase in disc height was due to restoration in the transplant group … Continue reading →

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stem cell therapy treatment for Spastic Paraplegia by dr alok sharma, mumbai, india – Video

Posted: Published on March 7th, 2014

stem cell therapy treatment for Spastic Paraplegia by dr alok sharma, mumbai, india improvement seen in just 5 days after stem cell therapy treatment for Spastic Paraplegia by dr alok sharma, mumbai, india. Stem Cell Therapy done date 7/1/20... By: Neurogen Brain and Spine Institute … Continue reading →

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21.Spinal Cord Injury(T5-6) Treated by Stem Cell Therapy(Before) – Video

Posted: Published on March 7th, 2014

21.Spinal Cord Injury(T5-6) Treated by Stem Cell Therapy(Before) Patient with T5-6 spinal cord injury: condition before treatment Before treatment, sensation remains only above the waist. Sweating remains only in the upper... By: Cells Center China … Continue reading →

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21.Spinal Cord Injury(T5-6) Treated by Stem Cell Therapy(After) – Video

Posted: Published on March 7th, 2014

21.Spinal Cord Injury(T5-6) Treated by Stem Cell Therapy(After) After treatment: The patient received four times of stem cell treatment in our center. His overall condition improved a lot after the treatment. The injury l... By: Cells Center China … Continue reading →

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Mesenchymal stem cells: the 'other' bone marrow stem cells …

Posted: Published on March 7th, 2014

What can mesenchymal stem cells do? Mesenchymal stem cells (MSCs) are an example of tissue or 'adult' stem cells. They are multipotent, meaning they can produce more than one type of specialized cell of the body, but not all types. MSCs make the different specialized cells found in the skeletal tissues. For example, they can differentiate or specialize into cartilage cells (chondrocytes), bone cells (osteoblasts) and fat cells (adipocytes). These specialized cells each have their own characteristic shapes, structures and functions, and each belongs in a particular tissue. Some early research suggested that MSCs might also differentiate into many different types of cells that do not belong to the skeletal tissues, such as nerve cells, heart muscle cells, liver cells and endothelial cells, which form the inner layer of blood vessels. These results have not been confirmed to date. In some cases, it appears that the MSCs fused together with existing specialized cells, leading to false conclusions about the ability of MSCs to produce certain cell types. In other cases, the results were an artificial effect caused by chemicals used to grow the cells in the lab. Mesenchymal stem cell differentiation: MSCs can make fat, cartilage and bone cells. They … Continue reading →

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Dad's race against time to take daughter to Disneyland before she goes blind

Posted: Published on March 7th, 2014

Dad's race against time to take daughter to Disneyland before she goes blind 5:46pm Friday 7th March 2014 in News By Tui Benjamin, Reporter Molly Bent, aged six A BRANDLESHOLME dad-of-three has enlisted old schoolfriends to help give his little girl experiences to last a lifetime before she goes blind. Last December, after 18 months of tests, police officer Chris Bent and his wife Eve were told the devastating news their six-year-old daughter Molly will eventually go blind. Molly has been diagnosed with Retinitis Pigmentosa, a degenerative eye condition which causes patches on the retina at the back of the eye. The youngster, who is now registered visually impaired, has black patches in her field of vision and suffers from night blindness, where she cannot see in low lights. There is no treatment or cure for the condition and Mollys sight will continue deteriorating until it goes completely but her family have no idea when this could be. But 27-year-old Chris, who now lives in Blackley, has enlisted his old Bury Church schoolfriends to tackle the Greater Manchester Run with him in May. The team hope their sporting efforts will raise enough money to take Molly on a trip to … Continue reading →

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Bone Marrow Transplant Program at Seattle Cancer Care Alliance Recognized for Its One-Year Survival Rates

Posted: Published on March 7th, 2014

Contact Information Available for logged-in reporters only Newswise SEATTLE The Fred Hutchinson Bone Marrow Transplant Program at Seattle Cancer Care Alliance (SCCA) was recently recognized by the Center for International Blood and Marrow Transplant Research (CIBMTR) for outperforming its expected one-year survival rate for allogeneic transplant patients. The results published by the CIBMTR, analyzed the National Marrow Donor Programs (NMDP) registry of 168 U.S. transplant centers over a three-year period for its 2013 Transplant Center-Specific Survival Report. The Fred Hutchinson Bone Marrow Transplant Program at SCCA pioneered the clinical use of bone marrow and stem cell transplantation more than 40 years ago and have performed more than 14,000 bone marrow transplants more than any other institution in the world. Today, the organization is one of just 13 stem cell transplant programs nationwide that exceeded its anticipated one-year survival rate for patients undergoing allogeneic transplants. This type of transplant uses stem cells from a donor who may or may not be related to the patient. Stem cell transplants, including bone marrow transplants, are used to treat a range of leukemias and lymphomas, as well as other diseases such as severe aplastic anemia and sickle cell disease. Comparing Transplant Centers Comparing transplant … Continue reading →

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Beyond The Brazilian Butt Lift: How Fat Became A Very Creative Surgical Tool

Posted: Published on March 7th, 2014

What hath Kim Kardashian wrought? Last week the American Society of Plastic Surgeons (ASPS) announced that butt augmentation surgery is up 16%. Butt wait, there's more: The smaller American Society for Aesthetic Plastic Surgery (ASAPS) outdid their colleagues by calling it 44% growth. Whichever group is right, one thing is clear: We, as a people, would like our rears rounded. The Brazilian Butt Lift has never been more popular. What the numbers dont tell you, however, is that what's driving real change in the cosmetic surgery landscape is not our collective desire for big bottoms, as Spinal Tap famously sang about, but something many of us are already far too familiar with: fat. As science allows doctors to use fat in new ways, they are flexing their creativity and employing fat to enhance areas that they might otherwise treat with implants, dermal fillers, and injectables with brands names such as Juvederms Voluma and Restylane. Weve taken away the need to go to a foreign substance, and were injecting fat. Its a change in how were thinking, says Dr. Robert X. Murphy, president of the American Society of Plastic Surgeons. While fat, specifically too much of it, has most typically been … Continue reading →

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CSC Announces FDA Approval Of Phase II Cancer Stem Cell …

Posted: Published on March 7th, 2014

IRVINE, Calif. (February 18, 2014) California Stem Cell, Inc. (CSC) announced today that the U.S. Food and Drug Administration (FDA) has approved the Companys application to begin a Phase II clinical trial exploring the potential of a patient-specific cancer immunotherapy in women with Stage III or IV ovarian, fallopian tube or primary peritoneal cancer. The randomized, double-blind study is the Companys second cancer therapy approved for clinical trials by FDA, bolstering its platform approach to treating late stage solid-tumor cancers. The Companys patient-specific approach to treating metastatic melanoma, recently approved to begin a Phase III trial, provided sufficient safety data to proceed directly to a Phase II study in ovarian cancer. Led by Chief Medical Officer Robert Dillman, M.D., the study design randomizes an estimated 99 adult female patients to two treatment arms. The treatment group will receive Ovapuldencel-T, which is a combination of autologous dendritic cells loaded with irradiated autologous tumor cells in GM-CSF. Ovapuldencel-T is created by first isolating cancer stem cells from the patients resected tumor sample, then enriching, inactivating and combining these cells with dendritic cells or antigen-presenting immune cells which are harvested from the patients blood. The control group will receive the MC treatment, harvested … Continue reading →

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FDA weighs possibility of allowing research into three-parent babies

Posted: Published on March 7th, 2014

FDA weighs possibility of allowing research into three-parent babies By Dennis Sadowski Catholic News Service WASHINGTON (CNS) -- Fertilization techniques that would create babies from the DNA of three or four people to prevent the transmission of inheritable genetic diseases are being questioned by ethicists and others who say the procedures fail basic ethical and moral standards. Chief among the concerns is that the techniques, which involve replacing a mother's mitochondria with that of an egg donor, would pass on genetic alterations with unknown implications for future generations. The techniques are controversial because they involve altering an embryo's DNA, leading to questions about whether the government should approve the creation of, in effect, genetically modified humans. In addition, the techniques rely upon in vitro fertilization, which the Catholic Church has long opposed as immoral. In IVF, a woman's eggs are removed, united with sperm in a laboratory, and then implanted in the womb of the mother or a surrogate. The two forms of the technology to overcome mitochondrial disease -- maternal spindle transfer and pronuclear transfer -- were discussed during a hearing called by the Cellular, Tissue and Gene Therapies Advisory Committee of the Food and Drug Administration Feb. 25-26. … Continue reading →

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