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Oklahoma House passes embryo protection bill

Posted: Published on February 26th, 2014

A bill that would make it a felony to knowingly destroy a human embryo for stem cell research or any other purpose cruised through the state House of Representatives on Tuesday by a vote of 73-14. It now goes to the state Senate. For me, and I believe a majority of Oklahomans, the real question is about life. When does life begin? I believe it begins at conception, said state Rep. Dan Fisher, one of the authors of House Bill 2070. I believe that Oklahoma needs to go down in history and on the record books as saying we are adamantly opposed to the intentional destruction of embryos. State Rep. Doug Cox, a Grove medical doctor, argued against the bill, saying that while he respects the intentions of the bills authors, it goes a little overboard and sends a message to the rest of the world that Oklahoma is closing the door on stem cell research. Cox said its too early to say where stem cell research will lead, but stem cells are being used in research into heart disease, cancer, diabetes, Alzheimers disease, Parkinsons disease, Huntingtons disease, Lou Gehrigs disease, muscular dystrophy and autism. Fisher said his bill would … Continue reading

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Genetic secret of mosquito resistance to DDT, bed net insecticides discovered

Posted: Published on February 26th, 2014

Researchers from LSTM have found that a single genetic mutation causes resistance to DDT and pyrethroids (an insecticide class used in mosquito nets). With the continuing rise of resistance the research, published in the journal Genome Biology, is key as scientists say that this knowledge could help improve malaria control strategies. The researchers, led by Dr Charles Wondji, used a wide range of methods to narrow down how the resistance works, finding a single mutation in the GSTe2 gene, which makes insects break down DDT so it's no longer toxic. They have also shown that this gene makes insects resistant to pyrethroids raising the concern that GSTe2 gene could protect mosquitoes against the major insecticides used in public health. Mosquitoes (Anopheles funestus) are vectors of malaria, and most strategies for combating the spread of the disease focus on control of mosquito populations using insecticides. The spread of resistance genes could hold back efforts to prevent the disease. The authors say that knowing how resistance works will help to develop tests, and stop these genes from spreading amongst mosquito populations. Charles Wondji said: 'We found a population of mosquitoes fully resistant to DDT (no mortality when they were treated with DDT) … Continue reading

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Brain cell activity regulates Alzheimers protein

Posted: Published on February 26th, 2014

PUBLIC RELEASE DATE: 25-Feb-2014 Contact: Michael C. Purdy purdym@wustl.edu 314-286-0122 Washington University School of Medicine Increased brain cell activity boosts brain fluid levels of a protein linked to Alzheimer's disease, according to new research from scientists at Washington University School of Medicine in St. Louis. Tau protein is the main component of neurofibrillary tangles, one of the hallmarks of Alzheimer's disease. It has been linked to other neurodegenerative disorders, including frontotemporal dementia, supranuclear palsy and corticobasal degeneration. "Healthy brain cells normally release tau into the cerebrospinal fluid and the interstitial fluid that surrounds them, but this is the first time we've linked that release in living animals to brain cell activity," said senior author David M. Holtzman, MD. "Understanding this link should help advance our efforts to treat Alzheimer's and other neurodegenerative disorders associated with the tau protein. The study appears online in the Journal of Experimental Medicine. Tau protein stabilizes microtubules, which are long columns that transport supplies from the center of the cell to the distant ends of the cell's branches. Some tau in the cell is not bound to microtubules. This tau can become altered and clump together inside brain cells, forming structures called tangles. Scientists have … Continue reading

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3D microgels on-demand offer new potential for cell research, the future of personalized medicine

Posted: Published on February 26th, 2014

TORONTO, ON Stars, diamonds, circles. Rather than your average bowl of Lucky Charms, these are three-dimensional cell cultures generated by an exciting new digital microfluidics platform, the results of which have been published in Nature Communications this week by researchers at the University of Toronto. The tool, which can be used to study cells in cost-efficient, three-dimensional microgels, may hold the key to personalized medicine applications in the future. We already know that the microenvironment can greatly influence cell fate, says Irwin A. Eydelnant, recent doctoral graduate from IBBME and first author of the publication. The important part of this study is that weve developed a tool that will allow us to investigate the sensitivity of cells to their 3D environment. Everyone wants to do three-dimensional (3D) cell culture, explains Aaron Wheeler, Professor and Canada Research Chair in Bioanalytical Chemistry at the Institute of Biomaterials & Biomedical Engineering (IBBME), the Department of Chemistry, and the Donnelly Centre for Cellular and Biomolecular Research (DCCBR) at the University of Toronto. Cells grown in this manner share much more in common with living systems than the standard two-dimensional (2D) cell culture format, says Wheeler, corresponding author of the study. More naturalistic, 3D cell … Continue reading

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Magnetic medicine

Posted: Published on February 26th, 2014

PUBLIC RELEASE DATE: 25-Feb-2014 Contact: Shawna Williams shawna@jhmi.edu 410-955-8236 Johns Hopkins Medicine Using tiny particles designed to target cancer-fighting immune cells, Johns Hopkins researchers have trained the immune systems of mice to fight melanoma, a deadly skin cancer. The experiments, described on the website of ACS Nano on February 24, represent a significant step toward using nanoparticles and magnetism to treat a variety of conditions, the researchers say. "Size was key to this experiment," says Jonathan Schneck, M.D., Ph.D., a professor of pathology, medicine and oncology at the Johns Hopkins University School of Medicine's Institute for Cell Engineering. "By using small enough particles, we could, for the first time, see a key difference in cancer-fighting cells, and we harnessed that knowledge to enhance the immune attack on cancer." Schneck's team has pioneered the development of artificial white blood cells, so-called artificial antigen-presenting cells (aAPCs), which show promise in training animals' immune systems to fight diseases such as cancer. To do that, the aAPCs must interact with immune cells known as naive T cells that are already present in the body, awaiting instructions about which specific invader they will battle. The aAPCs bind to specialized receptors on the T cells' surfaces … Continue reading

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Parents push for medical marijuana for kids with epilepsy

Posted: Published on February 25th, 2014

Nicole Gross was so desperate to find relief for her son's near-constant, debilitating seizures that she moved him from Naperville to Colorado so he could receive medical marijuana. Weeks after Chase Gross, 8, started taking a marijuana oil extract through a dropper, his mother said she saw a dramatic decrease in the number of daily seizures he had, allowing him to make developmental leaps such as dressing himself and learning new sign language words, since his condition has left him unable to speak. Gross became so convinced of pot's effectiveness in treating her son's severe epilepsy that she joined a growing number of parents and advocates lobbying Illinois to change its rules not only to add epilepsy to the list of qualifying conditions but to make medical marijuana available to children, as Colorado and several other states do. The drug's positive effects on Chase, his mother said, were "shocking." Public opinion has been shifting in favor of medical marijuana: Twenty states have legalized it, and the vast majority allow children access to it. But its use, particularly among juveniles, remains controversial. Marijuana is illegal under federal law, where it is classified as a dangerous substance with no medical value. While … Continue reading

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No, Vaccines Don't Cause Autism

Posted: Published on February 25th, 2014

S In 1998, there was a groundbreaking study telling parents that their children were at risk of getting autism from vaccines. Parents everywhere collectively gasped. After all, they had been told for years vaccines were the best way to prevent any number of unwanted diseases. Now they find out the very treatment they thought was making their children better could potentially result in devastating consequences, at least in the case of low-functioning Autism. The only problem was that same study published in the Lancet was later retracted. Its author, Andrew Wakefield, was shown to have falsified data. His "science" proved to be fraudulent, and riddled with conflicts of interest. His research was so void of ethics that the British General Medical Council removed him from the medical registry and he's no longer allowed to practice medicine in the United Kingdom. The damage, however, was done. As with so many other societal perceptions based on debunked science, vaccines causing autism is still a very real concern for many parents. In a survey published in Health Affairs in 2011, 30%-36% of parents were concerned that their children were given too many vaccines in the first 2 years of life, and that those … Continue reading

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Yoga for Young at Heart – Heart Disease, Stroke Treatment and Diet Tips in French. – Video

Posted: Published on February 25th, 2014

Yoga for Young at Heart - Heart Disease, Stroke Treatment and Diet Tips in French. Votre cur est un organe tonnant. Il pompe l'oxygne en continu et le sang riche en nutriments tout au long de votre corps, la vie. Nos modes de vie et de... By: Sur Le Yoga … Continue reading

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Giving stroke patients hypertension medication not helpful

Posted: Published on February 25th, 2014

CHICAGO, Feb. 24 (UPI) -- Giving stroke patients hypertension medication in the first 48 hours after a stroke does not reduce the likelihood of death or disability, U.S. researchers say. Stroke specialist Dr. Jose Biller, chairman of the Department of Neurology of Loyola University Medical Center, said the study involved more than 4,000 stroke patients in 26 hospitals across China, who were randomly assigned to receive blood pressure medications or to discontinue blood pressure medications. At 14 days or hospital discharge, there were no statistically significant differences between the groups in mortality or disability. Blood pressure often is elevated following a stroke, Biller said. "But in most cases, treatment is unnecessary because the blood pressure declines naturally over time, and lowering blood pressure may be contraindicated," Biller said in a statement. "It is important not to overtreat and cause low blood pressure, because the most important objective is to maintain adequate blood flow to the brain." The study, the China Anti-hypertensive Trial in Acute Ischemic Stroke, involved patients who had suffered ischemic strokes, which account for about 85 percent of all strokes. Such strokes are caused by blood clots that block blood flow to a part of the brain. The … Continue reading

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Study shows association between diabetes and stroke in women but not men

Posted: Published on February 25th, 2014

PUBLIC RELEASE DATE: 24-Feb-2014 Contact: Dr Gang Hu Gang.Hu@pbrc.edu 225-763-3053 Diabetologia New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that diabetes in women is associated with an increased risk of stroke, whereas the data do not show the same association among men. The research is by Dr Wenhui Zhao (the first author), Dr Gang Hu and colleagues at the Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA. Differences in incidence and mortality between sexes have been reported for various conditions, including stroke. More women than men tend to die from stroke in developed countries. For example, in the USA, 77,109 women and 52,367 men died from stroke in 2010. Women accounted for almost 60% of US stroke deaths in 2010. In the UK, 32,828 women and 20,358 men died from stroke in 2007. The authors prospectively investigated the sex-specific association of different levels of HbA1c with incident stroke risk among 10,876 male and 19,278 female patients with type 2 diabetes in the Louisiana State University Hospital-Based Longitudinal Study (LSUHLS). During a mean follow up of 6.7 years, 2,949 incident cases of stroke were identified. The authors calculated the risk of stroke … Continue reading

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