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New guidelines for women urge early attention to stroke

Posted: Published on February 7th, 2014

Long before a woman hits middle age, she and her doctor should be thinking about her risk of stroke and taking steps to reduce it, according to the first set of stroke guidelines aimed at women. The overall stroke risk for women is higher than it is for men, in part because women live longer. But the new guidelines from the American Heart Assn. underscore that many other factors may increase their risk as well, and many of them are evident when a woman is in her 20s and 30s. Some, like complications of pregnancy and menopause, are unique to women. Other risk factors including obesity, migraine with aura, atrial fibrillation and depression are more common in women than in men. Even risk factors that affect men and women equally, such as high blood pressure, smoking, diabetes and worrisome cholesterol readings, sometimes require different treatment in women. Current measures of a woman's stroke risk do not even consider her vulnerability before the age of 54, said Dr. Cheryl Bushnell, a neurologist at Wake Forest Baptist Health in Winston-Salem, N.C., and the lead author of the guidelines released Thursday. But since some risk factors occur when women are of childbearing age, … Continue reading

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HOLD: Stroke affects more women than men, yet little education exists

Posted: Published on February 7th, 2014

WASHINGTON -- A woman is more likely to die from a stroke than a man, yet prevention and treatment guidelines have always been targeted towards male patients, until now. The American Heart Association/American Stroke Association has just released the first set of stroke prevention guidelines specifically for women. "Stroke affects women in ways that are different from men," says Dr. Alex Dromerick, a professor of neurology at the Georgetown University School of Medicine. Hormones, birth control, pregnancy and other sex-related factors can influence a woman's risk of stroke. But with monitoring and treatment, that risk can be lowered. The recommendations -- published in the American Heart Association journal "Stroke" -- take aim at one of the main causes of cardiovascular problems: hypertension. Women who plan to take birth control pills should be tested for high blood pressure first, and that goes double if they smoke or get severe migraines. The guidelines also stress the importance of keeping blood pressure in check during pregnancy. Dromerick, who is also vice president for research at MedStar National Rehabilitation Network, says good prenatal care is essential. "One of the complications that can be associated with childbirth is called preeclampsia -- that is high blood … Continue reading

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Mobile stroke unit joins EMS response in Bellaire, West University

Posted: Published on February 7th, 2014

The University of Texas Health Science Center at Houston (UTHealth) Medical School, in partnership with Memorial Hermann-Texas Medical Center, today unveiled the countrys first mobile stroke unit. Staffed by a stroke team and equipped with a CT scanner, this specialized ambulance will run in conjunction with Emergency Medical Services of Bellaire, West University Place and Houston fire departments and is part of a three-year clinical trial to test whether it improves outcomes for stroke patients by speeding delivery of treatment with the clot-buster tPA (tissue plasminogen activator). It typically takes roughly an hour once a stroke patient arrives in the emergency room to receive treatment. So if we can actually put the emergency room in the ambulance and take the CT scanner to the patient, we could treat the patient at the scene with the medication and save that hour, said Dr. James C. Grotta, director of stroke research in the Center for Innovation & Research at Memorial Hermann-TMC and director of the mobile stroke unit consortium made up of stroke teams from Houston Methodist Hospital and St. Lukes Medical Center, local businesses and philanthropists. That hour could mean saving 120 million brain cells. Stroke occurs when blood flow to … Continue reading

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University scientists' work could lead to Parkinson's breakthrough

Posted: Published on February 7th, 2014

PUBLIC RELEASE DATE: 6-Feb-2014 Contact: Clare Parkin clare.parkin@sheffield.ac.uk 01-142-229-851 University of Sheffield Scientists at the University of Sheffield are part of a major European project which could revolutionise treatment for Parkinson's sufferers. One of the biggest challenges for treating Parkinson's is the unpredictable nature of the condition as it affects everyone differently and progresses in individuals in different ways. Now researchers from the University's INSIGNEO, Institute for in silico medicine, are among those working to create a computer model that will be able to accurately predict how a person's condition will develop over time. Professor Kevin Gurney, from INSIGNEO, said: "This project aims to lay the foundations for a step change in the treatment of Parkinson's disease. In the future health professionals will be able to tailor treatment to each individual and help people and their families to plan for the future. "Here at The University of Sheffield INSIGNEO is leading the way in in silico medicine. Working in partnership with Sheffield Teaching Hospitals NHS Foundation Trust we aim to put computers at the heart of healthcare making it possible to individualise and improve healthcare treatment and reduce costs. "We are very proud to be part of this research project … Continue reading

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News Review From Harvard Medical School — Gene, Pesticides Linked to Parkinson's Risk

Posted: Published on February 7th, 2014

February 6, 2014 News Review From Harvard Medical School -- Gene, Pesticides Linked to Parkinson's Risk People who have a variant gene and are exposed to certain pesticides may have a higher risk of Parkinson's disease, a new study finds. Researchers tested a variety of pesticides. They found that several of them interfere with the function of an enzyme called ALDH. This enzyme helps to break down chemicals that kill brain cells involved in making dopamine. People with Parkinson's disease have too little dopamine. Researchers asked about exposure to pesticides among people who were part of a study of Parkinson's risk in 3 California farming counties. In all, 360 people had Parkinson's and 816 people did not. Some people had a different (variant) version of a gene that provides instructions for making ALDH. Researchers looked at Parkinson's rates in people exposed to the pesticides that interfere with ALDH. Those with the variant gene were 2 to 5 times as likely to develop Parkinson's disease as those without the gene. The increase in risk varied for different pesticides. The journal Neurology published the study online February 5. HealthDay News wrote about it. By Robert H. Shmerling, M.D.Harvard Medical School What Is … Continue reading

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Brain Implants Hold Promise Restoring Combat Memory Loss

Posted: Published on February 7th, 2014

The Pentagon is exploring the development of implantable probes that may one day help reverse some memory loss caused by brain injury. The goal of the project, still in early stages, is to treat some of the more than 280,000 troops who have suffered brain injuries since 2000, including in combat in Iraq and Afghanistan. The Defense Advanced Research Projects Agency, or Darpa, is focused on wounded veterans, although some research may benefit others such as seniors with dementia or athletes with brain injuries, said Geoff Ling, a physician and deputy director of Darpas Defense Sciences office. Its still far from certain that such work will result in an anti-memory-loss device. Still, word of the project is creating excitement after more than a decade of failed attempts to develop drugs to treat brain injury and memory loss. The way human memory works is one of the great unsolved mysteries, said Andres Lozano, chairman of neurosurgery at the University of Toronto. This has tremendous value from a basic science aspect. It may have huge implications for patients with disorders affecting memory, including those with dementia and Alzheimers disease. At least 1.7 million people in the U.S. are diagnosed with memory loss … Continue reading

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World-first study into strokes and trauma

Posted: Published on February 7th, 2014

Interview subjects from the Goldfields will be part of a world-first research project looking at the effects of Acquired Communication Disorders in Aboriginal communities around WA. The project, Missing Voices: Communication Difficulties After Stroke and Traumatic Brain Injury in Indigenous Australians, led by researchers from Edith Cowan University, will examine indigenous victims of strokes or trauma to discover how their brain injury has affected their access to health services and their lives. Communication disorders can impair not only everyday tasks like using the telephone or giving instructions, but also expressions of emotions or identity critical to connecting with family and community, with the potential to isolate sufferers from culture. Despite indigenous Australians being more than twice as likely than non-indigenous Australians to suffer a stroke or traumatic brain injury, both of which are leading causes of ACD, they are still less likely to be diagnosed and have access to treatment and support services. Researchers will look to interview Aboriginal people with an ACD, as well as GPs and health professionals from six sites around WA, but say they are still looking for people to interview in the Goldfields. The findings will be used to provide information on how indigenous communities … Continue reading

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Families ramp up campaign to have multiple sclerosis drug Fampyra listed on Pharmaceutical Benefits Scheme

Posted: Published on February 7th, 2014

Sufferers from progressive multiple sclerosis (MS) are ramping up a campaign to have a new drug listed on the Pharmaceutical Benefits Scheme (PBS) when its Advisory Committee meets next month. Having trouble walking is a common symptom of MS, and the drug Fampyra is a potassium blocker designed to help those with MS to get around more easily. Two years ago there was an application to list the drug on the PBS but it was knocked back on the basis of unclear clinical evidence or cost effectiveness. The decision means Fampyra is available in Australia, but costs around $600 per month. Victorian woman Brenda Fisher's husband Mark was diagnosed with progressive MS in 1996, when the couple had three children, aged seven, four and two. Ms Fisher says the symptoms developed aggressively. "He's suddenly turning 37 and having to retire from work, and then it hits you - that this is actually going to be the rest of our life," Ms Fisher said. Ms Fisher became her husband's carer as he gradually lost mobility. These days, he does not leave the house. "He hasn't walked in quite a few years. He struggles to stand, has to be assisted, relies on … Continue reading

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Batten Disease: Spotlight on Stem Cell Research – Ann Tsukamoto – Video

Posted: Published on February 7th, 2014

Batten Disease: Spotlight on Stem Cell Research - Ann Tsukamoto (Part 3 of 4) Ann Tsukamoto, Ph.D. spoke at the "Spotlight on Batten Disease," an educational event presented at the CIRM Governing Board meeting on August 1... By: Fedora Innska … Continue reading

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New stem cell research removes reliance on human and …

Posted: Published on February 7th, 2014

A new study, published today in the journal Applied Materials & Interfaces, has found a new method for growing human embryonic stem cells, that doesn't rely on supporting human or animal cells. Traditionally, these stem cells are cultivated with the help of proteins from animals, which rules out use in the treatment of humans. Growing stem cells on other human cells risks contamination with pathogens that could transmit diseases to patients. The team of scientists led by the University of Surrey and in collaboration with Professor Peter Donovan at the University of California have developed a scaffold of carbon nanotubes upon which human stem cells can be grown into a variety of tissues. These new building blocks mimic the surface of the body's natural support cells and act as scaffolding for stem cells to grow on. Cells that have previously relied on external living cells can now be grown safely in the laboratory, paving the way for revolutionary steps in replacing tissue after injury or disease. Dr Alan Dalton, senior lecturer from the Department of Physics at the University of Surrey said: "While carbon nanotubes have been used in the field of biomedicine for some time, their use in human … Continue reading

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