Research led by Jesse C. Stewart, Ph.D., of the School of Science at Indiana University-Purdue University Indianapolis, is the first to find that treatment of depression before any apparent signs of cardiovascular disease can decrease the risk of future heart attacks and strokes by almost half. "Previous studies we and others have conducted indicate that depression is a risk factor for cardiovascular disease. But past depression treatment studies involving cardiac patients have not shown the anticipated cardiovascular benefits. So we asked ourselves, what if we treated depression before the onset of cardiovascular disease? Could that cut the risk of heart attack and stroke? Our results suggest that the answer is yes," said Dr. Stewart, associate professor of psychology in the School of Science at IUPUI and affiliated scientist of the Indiana University Center for Aging Research. The researchers followed 235 older, clinically depressed patients who were randomly assigned to standard care or to a collaborative care program involving antidepressants and psychotherapy. Among the 168 patients with no cardiovascular disease at the start of the study, those who received collaborative care to treat their depression had a 48 percent lower risk of heart attack or stroke over the next 8 years … Continue reading
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