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HRT cuts risk of repeat knee/hip replacement surgery by 40 percent

Posted: Published on January 22nd, 2014

PUBLIC RELEASE DATE: 22-Jan-2014 Contact: Emma Dickinson edickinson@bmj.com 44-020-738-36529 BMJ-British Medical Journal Hormone replacement therapy (HRT) taken regularly for six months after a knee or hip replacement seems to cut the risk of repeat surgery by around 40%, indicates a large population based study published online in the Annals of the Rheumatic Diseases. National data for England and Wales indicate that more than 2% of procedures typically have to be repeated within three years, primarily because of osteolysis (75% of cases). Osteolysis occurs when particles from the implant seep into the surrounding tissue, prompting an inflammatory response which then destroys the bone around the implant. And joint replacement surgery rates are set to rise substantially as the population ages and the prevalence of obesity increases, say the authors. The research team assessed the likelihood of repeat joint replacement surgery among women who required a first knee or hip replacement between 1986 and 2006. The women's details had been entered into the primary care General Practice Research Database (GPRD), which holds millions of anonymised medical records for patients across the UK. More than 21,000 eligible women who met the criteria had not used HRT, while more than 3500 had done so … Continue reading →

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HRT cuts risk of repeat surgery for hip, knee replacements

Posted: Published on January 22nd, 2014

Women who took hormone replacement therapy for more than a year after surgery were 50% less likely to require repeat surgery, according to new research. Photograph: Matt Kavanagh Hormone replacement therapy (HRT) taken for over a year by women after a knee or hip replacement appears to cut the risk of repeat surgery being needed by more than half, according to research published today. Figures from England and Wales show that two in every 100 operations have to be carried out again within three years because of osteolysis, where parts of the implant seep into surrounding tissue. The bodys immune system reacts against the seepage, causing inflammation which destroys the bone around the implants. Each year, 160,000 such operations are carried out in 400 hospitals, but the numbers are expected to rise sharply in coming years as the population ages. Women who took HRT for six months, or more, after surgery were 38 per cent less likely to require repeat surgery, while those who did so for more than a year were more than 50 per cent less likely to need it, researchers found. Joint replacements will also increase in coming years because of the impact of obesity on individuals, … Continue reading →

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Human Brain Development: Anita Bhattacharyya at TEDxUWMadison – Video

Posted: Published on January 22nd, 2014

Human Brain Development: Anita Bhattacharyya at TEDxUWMadison Anita Bhattacharyya is a Senior Scientist at the Waisman Center at the University of Wisconsin-Madison. Her research examines how the development of the cere... By: TEDxTalks … Continue reading →

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FASEB announces 2014 Science Research Conference: Skeletal Muscle Satellite and Stem Cells

Posted: Published on January 22nd, 2014

PUBLIC RELEASE DATE: 22-Jan-2014 Contact: Robin Crawford src@faseb.org 301-634-7010 Federation of American Societies for Experimental Biology Bethesda, MD This 2014 FASEB Science Research Conference focuses on recent advances in our understanding of the regulatory mechanisms controlling normal and abnormal functions of muscle-resident stem cells in regeneration, muscle homeostasis, hypertrophy, aging and muscle degenerative disease. Eight plenary sessions and three dedicated poster sessions will encompass the following major themes: transcriptional and posttranscriptional regulation of gene expression in stem cells, satellite cell heterogeneity and potential, stem cell signaling and environmental interactions, satellite cell quiescence, activation and renewal, non-satellite stem cells, satellite cell proliferation, commitment and differentiation, muscle stem cells in growth and hypertrophy, and muscle stem cells in aging, disease and therapeutics. This FASEB Conference increasingly attracts investigators in related fields who are interested in the rapid advances in muscle stem cell research, and interdisciplinary interactions are an important feature of this meeting. Collectively, this conference, which represents the only international conference that focuses exclusively on muscle satellite and stem cell populations, provides a venue to present cutting edge research, foster discussions, and promote collaborative interactions, with the goal of advancing a fundamental understanding of muscle-resident stem cells, and ultimately, translating this … Continue reading →

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Study Shows 1 in 5 Women with Ovarian Cancer Has Inherited Predisposition

Posted: Published on January 22nd, 2014

Contact Information Available for logged-in reporters only Newswise A new study conservatively estimates that one in five women with ovarian cancer has inherited genetic mutations that increase the risk of the disease, according to research at Washington University School of Medicine in St. Louis. Most women in the study would have been unaware of a genetic predisposition to ovarian cancer because they didnt have strong family histories that suggested it. The research, published Jan. 22 in Nature Communications, is the first large-scale analysis of the combined contributions of inherited and acquired mutations in a major cancer type. The inherited mutations by themselves are unlikely to cause ovarian cancer but may conspire with other genetic changes acquired over a womans lifetime to tip the balance toward cancer, the researchers said. Earlier studies that have looked at inherited susceptibility to ovarian cancer have focused on women with known family histories of the disease. For the current study, however, the researchers studied 429 women with ovarian cancer that appeared to develop sporadically, meaning the women did not have known family histories of the disease. Using advanced genomic analysis, we found that 20 percent of women with ovarian cancer had inherited mutations in a … Continue reading →

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Genetic counseling via telephone as effective as in-person counseling

Posted: Published on January 22nd, 2014

PUBLIC RELEASE DATE: 21-Jan-2014 Contact: Karen Teber km463@georgetown.edu Georgetown University Medical Center WASHINGTON Genetic counseling delivered over the telephone is as effective as face-to-face counseling, finds the largest randomized study to date comparing the two methods. The multi-center study, led by researchers at Georgetown Lombardi Comprehensive Cancer Center, was reported today in the Journal of Clinical Oncology. The landscape of genetic testing has broadened to include a range of diseases, and demand for testing and counseling has greatly increased because of direct-to-consumer marketing, says the study's lead investigator, Marc Schwartz, PhD, co-leader of Georgetown Lombardi's Cancer Prevention and Control Program. "It's important that all people interested in testing have access to thorough information so they can consider the implications of test results and interpret them in the context of family history," says Schwartz, who is also co-leader of the Fisher Center for Familial Cancer Research at Georgetown. "Counseling on the phone reduces costs and expands genetic counseling and testing access to rural areas, where counseling isn't always available." While this study was conducted with women considering testing for mutations in the breast or ovarian cancer genes BRCA1 and/or BRCA2, the findings "may extend to genetic counseling for other hereditary cancers … Continue reading →

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Stem Cell, Eye Stem Cell,Copd Stem Cell – Video

Posted: Published on January 22nd, 2014

Stem Cell, Eye Stem Cell,Copd Stem Cell http://yourservice.us/jeunesseglobal.html Stem cell therapy is an intervention strategy that introduces new adult stem cells into damaged tissue in order to ... By: Agus Saifudin … Continue reading →

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Anti Stem Cell, Stem Cell Spray, Fetal Stem Cell, Stem Cell Face By Dr. Renato Calabria – Video

Posted: Published on January 22nd, 2014

Anti Stem Cell, Stem Cell Spray, Fetal Stem Cell, Stem Cell Face By Dr. Renato Calabria http://yourservice.us/jeunesseglobal.html Stem cell therapy is an intervention strategy that introduces new adult stem cells into damaged tissue in order to ... By: Agus Saifudin … Continue reading →

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Diabetes Stem Cell, Stem Cell Paraplegic,Stem Cells Regenerate New Finger! – Video

Posted: Published on January 22nd, 2014

Diabetes Stem Cell, Stem Cell Paraplegic,Stem Cells Regenerate New Finger! http://yourservice.us/jeunesseglobal.html Stem cell therapy is an intervention strategy that introduces new adult stem cells into damaged tissue in order to ... By: Agus Saifudin … Continue reading →

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Crystalbartonnyc, Anti Aging Routine,Blind Girl Headed To China For Stem Cell Surgery – Video

Posted: Published on January 22nd, 2014

Crystalbartonnyc, Anti Aging Routine,Blind Girl Headed To China For Stem Cell Surgery http://yourservice.us/jeunesseglobal.html Stem cell therapy is an intervention strategy that introduces new adult stem cells into damaged tissue in order to ... By: Agus Saifudin … Continue reading →

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