PUBLIC RELEASE DATE: 25-Oct-2013 Contact: Zaal Kokaia Zaal.Kokaia@med.lu.se 46-705-365-917 Lund University Brain infarction or stroke is caused by a blood clot blocking a blood vessel in the brain, which leads to interruption of blood flow and shortage of oxygen. Now a reserach group at Lund University, Sweden, has taken an important step towards a treatment for stroke using stem cells. The research group shows in a new study, published in the scientific journal Brain, that so-called induced pluripotent stem cells have developed to mature nerve cells at two months after transplantation into the stroke-injured cerebral cortex of rats. These nerve cells have established contact with other important structures in the brain. The transplantation gave rise to improvement of the animals' mobility. The results are from studies in animals but the scientists are hopeful. ---The results are promising and represent a very early but important step towards a stem cell-based treatment for stroke in patients. However, it is important to underscore that further experimental studies are necessary to translate these findings into the clinic in a responsible way, says Olle Lindvall, senior consultant and professor of neurology and one of the scientists responsible for the study. In Sweden, about 30 000 … Continue reading
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