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Osiris Corrects Certain Inaccuracies in Media Reports

Posted: Published on October 24th, 2013

COLUMBIA, Md.--(BUSINESS WIRE)-- Osiris Therapeutics, Inc. (OSIR), issued a statement today correcting certain inaccuracies in media reports following the announcement of its favorable agreement with the United States Food and Drug Administration (FDA) regarding Grafix. It should be noted that Osiris may not be aware of and may not correct all current or future inaccuracies in media reports. About Osiris Therapeutics Osiris Therapeutics, Inc. is the leading stem cell company, having developed the worlds first approved stem cell drug, remestemcel-L, for graft versus host disease. Osiris products include Grafix and Ovation for acute and chronic wounds, Cartiform, a viable cartilage mesh for cartilage repair and the latest addition to Osiris line of products, OvationOS, a viable bone matrix. Osiris is a fully integrated company with capabilities in research, development, manufacturing and distribution. Osiris has developed an extensive intellectual property portfolio to protect the company's technology and commercial interests. Osiris, Grafix, Ovation and Cartiform are registered trademarks of Osiris Therapeutics, Inc. More information can be found on the company's website, http://www.Osiris.com. (OSIR-G) Forward-Looking Statements This press release contains forward-looking statements. Forward-looking statements include statements about our expectations, beliefs, plans, objectives, intentions, assumptions and other statements that are not historical facts. Words … Continue reading

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Multipotent Stem Cell Proteins Support Rejuvenation While Inhibiting Skin Cancer

Posted: Published on October 24th, 2013

San Diego, CA (PRWEB) October 24, 2013 Histogen, Inc., a regenerative medicine company developing solutions based on the products of cells grown under simulated embryonic conditions, announced that the Companys Chairman and CEO, Dr. Gail Naughton, will present today at the Tissue Engineering and Regenerative Medicine International Society (TERMIS) Asia Pacific Annual Meeting in Shanghai, China. Through its proprietary technology process that simulates the conditions of the embryonic environment, Histogen is uniquely able to trigger the de-differentiation of skin cells into multipotent stem cells without genetic manipulation. The cells express key stem cell markers including Oct4, Sox2 and Nanog, and secrete a distinctive composition of growth factors and other proteins known to stimulate stem cells in the body, regenerate tissues, and promote scarless healing. It is the soluble and insoluble compositions of multipotent proteins and growth factors resulting from this process that have been shown to both promote skin regeneration and induce controlled cell death in multiple skin cancers. The anti-aging and rejuvenation benefits of human multipotent stem cell proteins have been shown in several clinical studies, and have resulted in the materials use as a thriving next-generation ingredient for skin care, said Dr. Naughton. In parallel, we have also … Continue reading

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Vet-Stem, Inc. Founder and CEO Presents at TargetMeeting’s 3rd World Drug Discovery Online Conference

Posted: Published on October 24th, 2013

Poway, California (PRWEB) October 24, 2013 Dr. Robert Harman, Founder and CEO of Vet-Stem, Inc., a Regenerative Veterinary Medicine company in Southern California, presented at TargetMeetings 3rd World Drug Discovery Online Conference, October 15-17th, 2013. Topics of the web-based conference covered biotechnology and biopharmaceuticals, gene and cell therapy, as well as research and clinical trials. Target Meeting is a leading online life science conference organizer that proudly does not require any travel from participants. Participants like Dr. Harman were able to log into a secure conference track to hear live sessions, be part of question and answer forums, and give interactive presentations. Dr. Harmans presentation was on The Science and Business of Veterinary Regenerative Medicine, covering the use of stem cell therapy, types of stem cells, and uses in clinical veterinary medicine. Veterinary Regenerative Medicine is a discipline that seeks to replace or regenerate cells, tissue or organs, to restore or establish normal function. Stem cell medicines have been used clinically in veterinary medicine in advance of clinical use in human medicine. There are many commercial companies already offering autologous services and allogeneic stem cell medicines globally. -Dr. Harman. Dr. Harman explored the science and business of veterinary regenerative medicine, … Continue reading

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Stem cell therapy used locally in dogs

Posted: Published on October 24th, 2013

SIKESTON, MO (KFVS) - Stem cell therapycan bea very controversial issue, but now some veterinarians are using new techniques to harvest those cells. The cutting edge procedure helps fight degenerative diseases and has only been performed a few times in Missouri. Experts say regenerative medicine using stem cells is a less invasive and more cost effective alternative for dogs suffering from osteoarthritis and cartilage injuries. Googus is an 8 year old Boxer mix diagnosed with degenerative myelopathy. This terminal disease affects the spinal cord causing loss of control in the hind legs. "Even though they're unable to use their back legs they're still normal in their brain and they just don't understand why they can't walk," said Dr. Stephen Williams, Animal Health Center. "There's just not a good connection and transmission from the nerves to the back legs." But new technology could slow, if not stop, its progression. Dr. Williams is using stem cell therapy to counteract this and other degenerative diseases in dogs. "The stem cells from the patient are the ones that are going to benefit that same patient versus trying to take stem cells from a different dog and putting them in this dog," said Dr. Williams. … Continue reading

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Researchers apply brainpower to understanding neural stem cell differentiation

Posted: Published on October 24th, 2013

PUBLIC RELEASE DATE: 24-Oct-2013 Contact: Cristy Lytal lytal@med.usc.edu University of Southern California - Health Sciences How do humans and other mammals get so brainy? USC researcher Wange Lu, PhD, and his colleagues shed new light on this question in a paper that will be published in Cell Reports on October 24. The researchers donned their thinking caps to explain how neural stem and progenitor cells differentiate into neurons and related cells called glia. Neurons transmit information through electrical and chemical signals; glia surround, support and protect neurons in the brain and throughout the nervous system. Glia do everything from holding neurons in place to supplying them with nutrients and oxygen to protecting them from pathogens. By studying early mouse embryo neural stem cells in a petri dish, Lu and his colleagues discovered that a protein called SMEK1 promotes the differentiation of neural stem and progenitor cells. At the same time, SMEK1 keeps these cells in check by suppressing their uncontrolled proliferation. The researchers also determined that SMEK1 doesn't act alone: it works in concert with Protein Phosphatase 4 to suppress the activity of a third protein called PAR3 that discourages neurogenesis, or the birth of new neurons. With PAR3 out … Continue reading

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Investigators from Chongqing University Target Stem Cells

Posted: Published on October 24th, 2013

By a News Reporter-Staff News Editor at Stem Cell Week -- A new study on Stem Cell Research is now available. According to news reporting from Chongqing, People's Republic of China, by NewsRx journalists, research stated, "The purpose of this study was to investigate the influences of nanoscale wear particles derived from titanium/titanium alloy-based implants on integration of bone. Here we report the potential impact of titanium oxide (TiO2) nanoparticles on adhesion, migration, proliferation, and differentiation of mesenchymal stem cells (MSC) from the cellular level to the molecular level in the Wistar rat." The news correspondents obtained a quote from the research from Chongqing University, "A series of TiO2 nanoparticles (14 nm, 108 nm, and 196 nm) were synthesized and characterized by scanning electron microscopy and transmission electron microscopy, respectively. The TiO2 nanoparticles had negative effects on cell viability, proliferation, and the cell cycle of MSC in a dose-dependent and size-dependent manner. Confocal laser scanning microscopy was used to investigate the effects of particle internalization on adhesion, spreading, and morphology of MSC. The integrity of the cell membrane, cytoskeleton, and vinculin of MSC were negatively influenced by large TiO2 nanoparticles. The Transwell migration assay and a wound healing model suggested … Continue reading

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Cutting-edge procedure eliminates seizures

Posted: Published on October 24th, 2013

Over 3 million people suffer from epilepsy in the United States, and past treatment options have been limited to medication or open brain surgery. Now, a technique called laser ablation is giving neurosurgeons a less-invasive way to eliminate seizures. Dr. Shabbar Danish, director of functional neurosurgery at Robert Wood Johnson Hospital and assistant professor of surgery at Rutgers Robert Wood Johnson Medical School in New Brunswick, N.J., is part of one of the few teams in the country that perform this cutting-edge procedure. "If you could achieve the same exact outcome without opening up your head, why would you? said Danish. In all of medicine we're looking for minimally invasive procedures." Neurosurgeons insert a fiber-optic cable into a small hole in the skull that is just 3 millimeters in diameter. Then, using guided imagery, they thread it past blood vessels and healthy gray matter into the targeted brain lesion without damaging any healthy brain tissue. The laser uses thermal energy to wipe-out problematic tissue, while the surgical team monitors temperature in real time through magnetic resonance imaging (MRI). "By using a non-ionizing radiation source, we are able to deliver heat, kill what you want to destroy, and save what you … Continue reading

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Jerry Kill seeks epilepsy treatment in Grand Rapids

Posted: Published on October 24th, 2013

GRAND RAPIDS (WZZM) -- Michigan football fans probably became more aware of epilepsy after the Minnesota coach missed a recent game due to the disorder. Now, one media outlet reports Coach Jerry Kill took medical leave to seek treatment in Grand Rapids. The University of Minnesota will not confirm the report, but aMinneapolis Star Tribune sports writer WZZM 13 he is confident through his source that Kill was in Grand Rapids. If there's one man who's become the face of a chronic brain disorder, it's Minnesota Football Coach Jerry Kill. He's suffered five game day seizures since taking the position at Minnesota including one on the day of the University of Michigan game. Kill's advocacy for the life-threatening, memory-robbing disorder has also inspired thousands. Now he's seeking the best treatment not at the Mayo Clinic or a Minneapolis Hospital, but at a "renowned epilepsy clinic in Grand Rapids," according to the Minneapolis Star Tribune. HIPPA prevents us knowing if it's Saint Mary's Hauenstein Neuroscience Center or Spectrum Health's Epilepsy Center. Both are Level 4, the highest ranking centers. Dr. Brien Smith, Spectrum Health's Chief of Neurology, and board chair for the national Epilepsy Foundation says the clinic is attracting patients … Continue reading

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Jerry Kill reportedly seeks epilepsy treatment in Grand Rapids

Posted: Published on October 24th, 2013

GRAND RAPIDS (WZZM) -- Michigan football fans probably became more aware of epilepsy after the Minnesota coach missed a recent game due to the disorder. Now, one media outlet reports Coach Jerry Kill took medical leave to seek treatment in Grand Rapids. The University of Minnesota will not confirm the report, but aMinneapolis Star Tribune sports writer WZZM 13 he is confident through his source that Kill was in Grand Rapids. If there's one man who's become the face of a chronic brain disorder, it's Minnesota Football Coach Jerry Kill. He's suffered five game day seizures since taking the position at Minnesota including one on the day of the University of Michigan game. Kill's advocacy for the life-threatening, memory-robbing disorder has also inspired thousands. Now he's seeking the best treatment not at the Mayo Clinic or a Minneapolis Hospital, but at a "renowned epilepsy clinic in Grand Rapids," according to the Minneapolis Star Tribune. HIPPA prevents us knowing if it's Saint Mary's Hauenstein Neuroscience Center or Spectrum Health's Epilepsy Center. Both are Level 4, the highest ranking centers. Dr. Brien Smith, Spectrum Health's Chief of Neurology, and board chair for the national Epilepsy Foundation says the clinic is attracting patients … Continue reading

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Many Kids With Autism on Multiple Medications, Study Finds

Posted: Published on October 24th, 2013

By Serena Gordon HealthDay Reporter TUESDAY, Oct. 22 (HealthDay News) -- Children with autism in the United States routinely take one or more prescription medications, even though little evidence exists regarding the drugs' safety or effectiveness for treating the neurodevelopmental condition, a new study finds. The study of almost 34,000 children with an autism spectrum disorder found nearly two-thirds were prescribed at least one medication. Within that group, more than one-third were given two medications, and one in seven took three drugs. "There are a lot of children who are being treated with psychotropic medications with unknown effects for benefits and harms," said the study's senior author, Dr. Anjali Jain, a managing consultant with the Falls Church, Va.-based Lewin Group, a health care consulting firm. "I hope everyone -- parents and providers -- will consider these medications with caution," she added. Children with autism have impaired communication and social skills, and often exhibit repetitive behaviors. In the United States, about one in 88 children has been diagnosed with an autism spectrum disorder, which can range from mild, as in Asperger syndrome, to severe autism. The study, released online Oct. 21 in Pediatrics, looked at the use of psychotropic medications, which … Continue reading

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