Early and continuous use ofOcrevus(ocrelizumab) significantly slows disability progression and delays the time until wheelchair reliance in people with primary progressive multiple sclerosis (PPMS), new Phase 3 data spanning more than six years show. Findings fromthe ORATORIO trial, comparing immediate use with a two-year delay, support Ocrevus sustained and long-term benefits, and highlight gains realized through earlier treatment initiation in PPMS patients Continue reading →

This is an interesting concept that makes sense. Like the nine-hole peg test that some neurologists use to test finger dexterity, and like some apps that attempt to measure this, monitoring how quickly, and in what manner I can move my fingers might allow a physician to track the progression of my disease. It could be done remotely and frequently Continue reading →

November 26, 2020 By HSC, Shared Health Study published in U.S. Continue reading →

Clene Nanomedicine is trying to set a new gold standard in neurodegenerative diseases through the development of a new class of drugs called bioenergetic nanotherapeutics that harnesses the properties of gold nanocrystals. The gold nanocrystals are used to amplify bioenergetic reactions in patients in order to drive intracellular biological reactions. Bioenergetic nanotherapeutics are a clean break from pharmaceutical drug development that uses classical synthetic chemistry, Clene Chief Executive Officer Rob Etherington told BioSpace in an interview. Continue reading →

This article was originally published here Neurol Ther. 2020 Nov 23. doi: 10.1007/s40120-020-00223-2 Continue reading →

There are important reasons to study chronic pain and PTSD together, says Matthew J. Bair, MD, MS. Chronic pain and PTSD co-occur frequently.This comorbidity leads to significant adverse effects for patients, and their co-occurrence is worse for patients with only one of these conditions.The comorbidity has negative additive effects on pain and PTSD symptoms, including pain intensity, pain-related disability, worse quality of life, depression, and anxiety, all of which may complicate treatment Continue reading →