Public release date: 3-Oct-2013 [ | E-mail | Share ] Contact: Anne DeLotto Baier abaier@health.usf.edu 813-974-3303 University of South Florida (USF Health) Tampa, FL (Oct. 3, 2013) -- University of South Florida researchers have suggested a new view of how stem cells may help repair the brain following trauma. In a series of preclinical experiments, they report that transplanted cells appear to build a "biobridge" that links an uninjured brain site where new neural stem cells are born with the damaged region of the brain. Their findings were recently reported online in the peer-reviewed journal PLOS ONE. "The transplanted stem cells serve as migratory cues for the brain's own neurogenic cells, guiding the exodus of these newly formed host cells from their neurogenic niche towards the injured brain tissue," said principal investigator Cesar Borlongan, PhD, professor and director of the USF Center for Aging and Brain Repair. Based in part on the data reported by the USF researchers in this preclinical study, the U.S. Food and Drug Administration recently approved a limited clinical trial to transplant SanBio Inc's SB632 cells (an adult stem cell therapy) in patients with traumatic brain injury. Stem cells are undifferentiated, or blank, cells with the … Continue reading
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