Page 4,900«..1020..4,8994,9004,9014,902..4,9104,920..»

Genetics in Medicine publishes special issue dedicated to genomics in electronic health records

Posted: Published on September 20th, 2013

Public release date: 19-Sep-2013 [ | E-mail | Share ] Contact: Kathy Ridgely Beal kbeal@acmg.net 301-238-4582 American College of Medical Genetics September 19, 2013 Bethesda, MD Genetic tests can now tell us whether we are at increased risk of various cancers, heart or kidney disease, asthma and a number of other conditions. Other genetic tests can tell whether you will respond to certain medicines or be harmed by side effects linked to your genetic code. But harnessing that information to benefit individual patients and prevent illnesses in others will require that doctors have access to genomic information for each patient. As health records are converted to digital form, the most likely place to store and retrieve genomic information will be Electronic Health Records (EHR). But when and how that happens will depend on having good models to build upon. Now, in the first collection of its kind, the October 2013 issue of Genetics in Medicine, the official peer-reviewed journal of the American College of Medical Genetics and Genomics, provides a series of research articles detailing challenges and solutions for integrating genomic data into EHR. The issue features the insights of research teams actively engaged in integrating genomic medicine into clinical … Continue reading

Comments Off on Genetics in Medicine publishes special issue dedicated to genomics in electronic health records

BIND Therapeutics Announces Pricing of Initial Public Offering

Posted: Published on September 20th, 2013

CAMBRIDGE, Mass.--(BUSINESS WIRE)-- BIND Therapeutics, Inc., a clinical-stage nanomedicine platform company developing targeted and programmable therapeutics called Accurins, announced today the pricing of its initial public offering of 4,700,000 shares of its common stock at a public offering price of $15.00 per share, before underwriting discounts and commissions. The shares are expected to begin trading on The NASDAQ Global Select Market under the ticker symbol BIND on September 20, 2013. In addition, BIND has granted the underwriters a 30-day option to purchase up to an additional 705,000 shares of common stock at the same price to cover over-allotments, if any. The offering is expected to close on September 25, 2013, subject to customary closing conditions. Credit Suisse (USA) LLC and Cowen and Company, LLC are acting as joint book-running managers for the offering. Stifel Nicolaus & Company, Incorporated and JMP Securities LLC are acting as co-managers. A registration statement relating to these securities has been filed with, and declared effective by, the U.S. Securities and Exchange Commission on September 19, 2013. The offering is being made only by means of a written prospectus forming part of the effective registration statement. Copies of the prospectus relating to and describing the terms … Continue reading

Comments Off on BIND Therapeutics Announces Pricing of Initial Public Offering

ACT Files Investigational New Animal Drug (INAD) Application with FDA to Treat 10 Different Disease Indications Using …

Posted: Published on September 19th, 2013

MARLBOROUGH, Mass.--(BUSINESS WIRE)-- Advanced Cell Technology, Inc. ("ACT"; OTCBB: ACTC), a leader in the field of regenerative medicine, announced today that it has filed an Investigational New Animal Drug (INAD) application with the Food and Drug Administration (FDA) to test its proprietary off-the-shelf mesenchymal stem cells (MSC) in a range of different disease indications. The studies will evaluate the safety and efficacy of ACTs pluripotent stem cell-derived MSCs in ten spontaneous disease models in dogs, which are similar to various human inflammatory and immune-mediated diseases. While these companion animal studies represent research intended for ultimate licensure of veterinary therapeutics, ACT anticipates that the trial results may be relevant to its path to clinical trials in human patients and may provide a more robust assessment of safety and therapeutic endpoints than what can be obtained from inbred rodent models. The INAD is directed to ten canine disorders corresponding to hepatitis, glomerulonephritis, osteoarthritis, Crohns disease, inflammatory bowel disease, spinal cord/disc disease, meningoencephalitis, hemolytic anemia, pancreatitis and sepsis. This INAD filing extends our ongoing work with world experts in veterinary and regenerative medicine , said Robert Lanza, M.D., chief scientific officer of ACT. Preliminary studies in rodents have shown that our hESC-derived MSCs … Continue reading

Posted in Stem Cell Human Trials | Comments Off on ACT Files Investigational New Animal Drug (INAD) Application with FDA to Treat 10 Different Disease Indications Using …

OncoMed Pharmaceuticals Initiates Phase 1b/2 Clinical Trial of Demcizumab (Anti-DLL4) in Combination with Paclitaxel …

Posted: Published on September 19th, 2013

REDWOOD CITY, Calif., Sept. 19, 2013 (GLOBE NEWSWIRE) -- OncoMed Pharmaceuticals, Inc. (OMED), a clinical-stage company developing novel therapeutics that target cancer stem cells (CSCs), or tumor-initiating cells, today announced that it has started a Phase 1b/2 clinical trial of its anti-cancer stem cell product candidate, demcizumab (OMP-21M18) in ovarian cancer. The trial will enroll patients at the MD Anderson Cancer Center in Houston, TX, and is being funded in part under an ovarian cancer National Cancer Institute SPORE Grant Program. In this Phase 1b/2 trial, demcizumab is being tested in combination with paclitaxel in patients with platinum-resistant ovarian cancer, fallopian tube cancer or primary peritoneal cancer. Following a Phase 1b safety run-in, a Phase 2 clinical trial will proceed in these patients. The primary endpoints of the Phase 2 part of the trial will be to determine the progression-free survival and response rate of the novel demcizumab with paclitaxel combination. Key secondary and exploratory endpoints include overall survival, biomarker endpoints and safety. Dr. Robert Coleman, Professor & Vice Chair, Clinical Research, Department of Gynecologic Oncology and Reproductive Medicine at The University of Texas MD Anderson Cancer Center in Houston, TX, and the Principal Investigator who treated the first patient … Continue reading

Comments Off on OncoMed Pharmaceuticals Initiates Phase 1b/2 Clinical Trial of Demcizumab (Anti-DLL4) in Combination with Paclitaxel …

Orlando Plastic Surgeon Dr. Daryl Wier Joins the Aesthetic Surgery Center of Winter Park

Posted: Published on September 19th, 2013

Winter Park, FL (PRWEB) September 19, 2013 The Aesthetic Surgery Center of Winter Park is adjacent to the Breast Center at the Bougainvillea Clinique. As one of Orlandos most highly respected general surgeons with over 30 years of experience in breast surgery, Dr. Wier will expand and improve the Breast Centers services for breast cancer patients. By providing general surgery services, Dr. Wier and Dr. Hartog together will be able to provide immediate breast reconstruction using autologous fat grafting (AFT) at the same time as a mastectomy procedure. This service is particularly valuable for patients who choose prophylactic mastectomy procedures due to a strong family history of breast cancer, or a BRCA-positive condition (breast cancer early onset). Additionally the Center will be able to provide the full spectrum of breast surgery procedures for breast cancer, breast reconstruction and cosmetic breast surgery. Initiating autologous fat grafting at the time of the mastectomy has numerous advantages, the most obvious of which is that the patient can leave the facility with a small breast mound, and some fullness in the breast, says Dr. Jeffrey Hartog, the Medical Director of the Bougainvillea Clinique. This is a great advantage when post-mastectomy patients try to wear … Continue reading

Posted in Aesthetic Surgery | Comments Off on Orlando Plastic Surgeon Dr. Daryl Wier Joins the Aesthetic Surgery Center of Winter Park

Stem Cell Therapy Treatment for Autism with MR by Dr Alok Sharma, Mumbai, India – Video

Posted: Published on September 19th, 2013

Stem Cell Therapy Treatment for Autism with MR by Dr Alok Sharma, Mumbai, India Improvement seen in just 3 months after Stem Cell Therapy Treatment for Autism with MR by Dr Alok Sharma, Mumbai, India After Stem Cell Therapy 1. Her sitting tolerance has improved from 15... By: Neurogen Brain and Spine Institute … Continue reading

Comments Off on Stem Cell Therapy Treatment for Autism with MR by Dr Alok Sharma, Mumbai, India – Video

Stem Cell Therapy Treatment for Cerebellar Ataxia by Dr Alok Sharma, Mumbai, India – Video

Posted: Published on September 19th, 2013

Stem Cell Therapy Treatment for Cerebellar Ataxia by Dr Alok Sharma, Mumbai, India Improvement seen in just 3 Months after Stem Cell Therapy Treatment for Cerebellar Ataxia by Dr Alok Sharma, Mumbai, India. Stem Cell Therapy done at Dr Alok... By: Neurogen Brain and Spine Institute … Continue reading

Comments Off on Stem Cell Therapy Treatment for Cerebellar Ataxia by Dr Alok Sharma, Mumbai, India – Video

Hitguj Stem Cell Therapy – Video

Posted: Published on September 19th, 2013

Hitguj Stem Cell Therapy For more info log on to http://www.24taas.com Like us on https://www.facebook.com/Zee24Taas Follow us on https://twitter.com/zee24taasnews. By: Zee24Taas … Continue reading

Comments Off on Hitguj Stem Cell Therapy – Video

NIH Grant to support Mount Sinai Research Program to Create Biological Network Model of Alzheimer’s Disease in …

Posted: Published on September 19th, 2013

New York (PRWEB) September 18, 2013 Scientists from the Icahn School of Medicine at Mount Sinai, in partnership with the New York Stem Cell Foundation (NYSCF), and other institutions, have been awarded a multi-year grant from the National Institutes of Health (NIH) to study Alzheimers disease. This study will apply innovative analytical methods to large-scale molecular, cellular, and clinical data from Alzheimers patients to construct biological network models and gain new insights into the complex mechanisms of the disease, and identify potential therapeutic targets. Biological network models are complex mathematical representation of large amounts of data. These networks provide a unified map that integrates not only the key genes involved in a disease but also the biological pathways that those genes control. The NIH grant will enable the research team at Mount Sinai and partner institutions to build upon the discovery published earlier this year in the journal Cell of a network of genes as a key mechanism driving Late Onset Alzheimers Disease (LOAD) through involvement in the inflammatory response in the brain. Eric Schadt, PhD, The Jean C. and James W. Crystal Professor of Genomics at the Icahn School of Medicine at Mount Sinai, and Director of the Icahn … Continue reading

Posted in Stem Cell Human Trials | Comments Off on NIH Grant to support Mount Sinai Research Program to Create Biological Network Model of Alzheimer’s Disease in …

StemCells, Inc. Announces New Preclinical Data Showing HuCNS-SC(R) Cells Preserve Visual Function by Keeping …

Posted: Published on September 19th, 2013

NEWARK, Calif., Sept. 18, 2013 (GLOBE NEWSWIRE) -- StemCells, Inc. (STEM) today announced the publication of preclinical data confirming that the Company's proprietary HuCNS-SC cells (purified human neural stem cells) preserve photoreceptor cells and visual function in a widely used model of retinal degeneration. The data show not only that HuCNS-SC cells preserve the number of photoreceptors that would otherwise be lost, but also that the surviving photoreceptors appear healthy and normal, and maintain their synaptic connection to other important cells necessary for visual function. The study was published in Investigative Ophthalmology and Visual Science (IVOS), the journal of the Association for Research in Vision and Ophthalmology, and is available at (http://www.iovs.org/content/early/recent.) These results are highly relevant to disorders of vision loss, the most notable of which is age-related macular degeneration (AMD), which afflicts approximately 30 million people worldwide. "This study demonstrates that, at the cellular and sub-cellular level, the surviving photoreceptors have all the components that characterize a healthy and normal photoreceptor, and they have the correct synaptic connections," said Nicolas Cuenca, PhD, Professor in the Department of Physiology, Genetics and Microbiology at the University of Alicante, Spain, and lead author of the paper. "The robust anatomical preservation of … Continue reading

Posted in Stem Cell Human Trials | Comments Off on StemCells, Inc. Announces New Preclinical Data Showing HuCNS-SC(R) Cells Preserve Visual Function by Keeping …

Page 4,900«..1020..4,8994,9004,9014,902..4,9104,920..»