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Boyd "Rainmaker" Melson, Professional Athlete and Advocate for Spinal Cord Injury Treatment, Signs on as Advisory …

Posted: Published on September 19th, 2013

Lexington, MA (PRWEB) September 18, 2013 Melson is a gifted professional boxer who donates all of the money that he earns in the ring to spinal cord injury research. His advocacy efforts have been profiled on Emmy Award winning HBO series Real Sports, ESPN.com, Sports Illustrated and Yahoo. He is a founder of the organization Team Fight to Walk (http://www.teamfighttowalk.com), which through professional boxers and other athletes raises money for JustADollarPlease (http://www.justadollarplease.org), which supports efforts to bring clinical trials of adult stem cell treatments for spinal cord injury to the United States. In the United States alone, where a spinal cord injury occurs every 43 minutes, there are 300,000 people living with the tragic after-effects, said Melson. Of those, 40,000 are US Armed Forces Veterans. The exploding field of regenerative medicine holds great promise for the treatment of these injuries. My dearest friend in this world, Christan, who is the inspiration behind my passion for all things relating to spinal cord injury treatment, lives every day with the challenges resulting from a spinal cord injury. I have experienced firsthand, in her case, how adult stem cells can improve the quality of life. I live to help Christan and others like … Continue reading

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Signal gradients in 3-D guide stem cell behavior

Posted: Published on September 18th, 2013

Sep. 18, 2013 Scientists know that physical and biochemical signals can guide cells to make, for example, muscle, blood vessels or bone. But the exact recipes to produce the desired tissues have proved elusive. Now, researchers at Case Western Reserve University have taken a step toward identifying that mix by developing an easy and versatile way of forming physical and biochemical gradients in three dimensions. Ultimately, one of their goals is to engineer systems to manipulate stem cells to repair or replace damaged tissues and organs. "If we can control the spatial presentation of signals, we may be able to have more control over cell behavior and enhance the rate and quality of tissue formation," said Eben Alsberg, an associate professor of biomedical engineering and orthopaedic surgery at Case Western Reserve and senior author of the research. "Many tissues form during development and healing processes at least in part due to gradients of signals: gradients of growth factors, gradients of physical triggers." Alsberg, postdoctoral scholar Oju Jeon and graduate student Daniel S. Alt of Case Western Reserve, and Stephen W. Linderman, a visiting undergraduate on a National Science Foundation Research Experience for Undergraduates summer fellowship, tested their system on mesenchymal … Continue reading

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Structure Of The Brain May Predispose You To Chronic Pain

Posted: Published on September 18th, 2013

September 18, 2013 [ Watch the Video: Pain in the Brain with Dr. Vania Apkarian ] Brett Smith for redOrbit.com Your Universe Online By using brain scans on chronic pain sufferers, neuroscientists based in Chicago have discovered a connection between the brain and experiencing chronic pain, according to a report in the journal Pain. We may have found an anatomical marker for chronic pain in the brain, said study author Vania Apkarian, a professor of physiology at Northwestern University Feinberg School of Medicine. About 23 percent of individuals with low back pain are chronic, or long-term, sufferers. While some sources of pain can be seen at the site of injury, recent research indicates that the brain may be more involved with chronic pain than previously thought. Currently we know very little about why some patients suffer chronic low back pain, said Dr. Debra Babcock, a program director at the National Institute of Neurological Disorders and Stroke (NINDS). The earlier we detect pain will become chronic, the better we may be able to treat patients. The research team began by scanning the brains of 46 volunteers who reported low back pain for about three months before coming to a hospital for … Continue reading

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The Invisible Brain Injury Project Surpasses $100,000 in Donations

Posted: Published on September 18th, 2013

Denver, CO (PRWEB) September 17, 2013 The Invisible Brain Injury Project (http://www.invisibleheadinjury.com), a partnership between the Tug McGraw Foundation and CereScan Corp. of Denver, CO, and others has recently surpassed the $100k mark in initial funding. This project is specifically geared to seek new and more efficient identification of and treatment for invisible wounds such as Mild-to-Moderate Traumatic Brain Injury (mTBI). The Invisible Brain Injury Project is aimed at addressing mTBI sustained by current and former military members and is an endeavor sponsored in part by CereScan, a clinical facility dedicated to state of the art functional brain imaging for the identification of a wide array of brain based disorders. John Kelley, Chairman and CEO of CereScan comments, We are delighted to see the donations to this project continue to increase. When combining the power and capabilities of both The Tug McGraw Foundation and CereScan, the Invisible Brain Injury Project stands as a beacon of hope for the thousands of brain injured service members who are seeking assistance. The continued growth of donations to this project speaks to an increasing national awareness of the problems confronted by our returning warfighters who have sustained an mTBI and the demonstrated track record … Continue reading

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Genzyme wins regulatory approval in Europe of its second drug to treat multiple sclerosis

Posted: Published on September 18th, 2013

By Robert Weisman / Globe Staff/ September 17, 2013 European regulators Tuesday put their stamp of approval on Genzymes multiple sclerosis drug candidate Lemtrada, giving the Cambridge biotechnology company its second MS treatment on the market in the European Union only weeks after it was first approved there. The move vindicated French drug maker Sanofi SAs decision to pay $20.1 billion for Genzyme in 2011, a deal that hinged on the potential of Lemtrada, then an experimental therapy. While it has not yet been approved for sale in the United States the Food and Drug Administration is expected to rule on Genzymes application by the end of the year Lemtrada won the European Commissions blessing both for patients who have taken other MS drugs as well as newly diagnosed patients. Full story for BostonGlobe.com subscribers. Copyright 2013 Globe Newspaper Company. Get the full story with unlimited access to BostonGlobe.com. Just 99 for 4 weeks. Get Access Now View original post here: Genzyme wins regulatory approval in Europe of its second drug to treat multiple sclerosis … Continue reading

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Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Acceptance for Review of the New Drug Submission of …

Posted: Published on September 18th, 2013

MISSISSAUGA, ON, Sept. 18, 2013 /CNW/ - Sunovion Pharmaceuticals Canada Inc. (Sunovion) today announced that Health Canada has accepted for review the company's New Drug Submission (NDS) for eslicarbazepine acetate for use as a once-daily adjunctive therapy in the treatment of partial-onset seizures in patients 18 years of age and older with epilepsy. The efficacy and safety of eslicarbazepine acetate as an adjunctive or monotherapy treatment for partial-onset seizures in adults living with epilepsy has not yet been established. "The acceptance of our eslicarbazepine acetate submission is an important milestone not only for our company, but for thousands of Canadians living with and affected by epilepsy," said Douglas Reynolds, President, Sunovion Pharmaceuticals Canada Inc. "Adequate seizure control remains an unmet medical need for a significant number of patients and Sunovion is committed to providing a treatment option to address this need. If approved, eslicarbazepine acetate may offer adult patients an effective,adjunctive treatment option for better managing partial-onset seizures". The NDS for eslicarbazepine acetate is supported by data from three Phase III randomized, double-blind, placebo-controlled 12-week maintenance trials of similar study design, which included more than 1,400 patients with partial-onset seizures. In these trials, treatment with eslicarbazepine acetate demonstrated statistically significant … Continue reading

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Nicole Gibson, Transgender Model, Walks In London Fashion Week

Posted: Published on September 18th, 2013

Days before her planned gender reassignment surgery, a transgender model wowed audiences on the catwalk at London's Fashion Week, just two years after beginning hormone replacement therapy. Nicole Gibson, 32, took part in the Catwalk For Change campaign for Models of Diversity, a fashion showcase that sought to challenge the lack of diversity within the fashion industry. "The fashion show was amazing," said Gibson. "They say you have not really made it as a model until you walk along the catwalk in a sheer dress with your nipples showing -- and here I was doing it in my first show. Luckily, thanks to the hormones, I have quite a nice pair now. I didnt have time to get nervous, I was just so excited." Up until her 20s, Gibson identified as a gay man. She then started to wear women's clothing for a number of years before deciding to begin hormone replacement therapy. "To me it is just something that I have to do," stated Gibson. "It is like having two horns on my head that I have to get rid of to become the person that I have always felt I was inside.' Prior to embarking on her modeling … Continue reading

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Study: Different hormone therapy formulations may pose different risks for heart attack and stroke

Posted: Published on September 18th, 2013

Public release date: 18-Sep-2013 [ | E-mail | Share ] Contact: Sally Stewart sally.stewart@cshs.org 310-248-6566 Cedars-Sinai Medical Center LOS ANGELES (Embargoed Until 9 a.m. EDT/6 a.m. PDT on Sept. 18, 2013) Post-menopausal women whose doctors prescribe hormone replacement therapy for severe hot flashes and other menopause symptoms may want to consider taking low doses of Food and Drug Administration-approved bioidentical forms of estrogen or getting their hormones via a transdermal patch. A new observational study shows bioidentical hormones in transdermal patches may be associated with a lower risk of heart attack and FDA-approved products -- not compounded hormones -- may be associated with a slightly lower risk of stroke compared to synthetic hormones in pill form. "If confirmed by future randomized trials, these findings may be significant because for the past decade, many women who experienced severe menopause symptoms opted not to use hormone therapy because of the reported increased risk of stroke and heart attacks," said Chrisandra Shufelt, MD, director of the Women's Hormone and Menopause Program at the Barbra Streisand Women's Heart Center in the Cedars-Sinai Heart Institute. Shufelt said the study's findings are not conclusive and are based on observational follow-up, not a randomized clinical trial. Additionally, … Continue reading

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Different Hormone Therapy Formulations may Pose Different Risks for Heart Attack and Stroke

Posted: Published on September 18th, 2013

Newswise LOS ANGELES (EMBARGOED until 9 a.m. EDT/6 a.m. PDT on Sept. 18, 2013) Post-menopausal women whose doctors prescribe hormone replacement therapy for severe hot flashes and other menopause symptoms may want to consider taking low doses of Food and Drug Administration-approved bioidentical forms of estrogen or getting their hormones via a transdermal patch. A new observational study shows bioidentical hormones in transdermal patches may be associated with a lower risk of heart attack and FDA-approved products -- not compounded hormones -- may be associated with a slightly lower risk of stroke compared to synthetic hormones in pill form. If confirmed by future randomized trials, these findings may be significant because for the past decade, many women who experienced severe menopause symptoms opted not to use hormone therapy because of the reported increased risk of stroke and heart attacks, said Chrisandra Shufelt, MD, director of the Womens Hormone and Menopause Program at the Barbra Streisand Womens Heart Center in the Cedars-Sinai Heart Institute. Shufelt said the studys findings are not conclusive and are based on observational follow-up, not a randomized clinical trial. Additionally, all types of hormone therapy had similar rates of total cardiovascular outcomes and all-cause mortality, the study … Continue reading

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Hormone therapy formulations may pose varying risks for heart attack and stroke

Posted: Published on September 18th, 2013

Sep. 18, 2013 Post-menopausal women whose doctors prescribe hormone replacement therapy for severe hot flashes and other menopause symptoms may want to consider taking low doses of Food and Drug Administration-approved bioidentical forms of estrogen or getting their hormones via a transdermal patch. A new observational study shows bioidentical hormones in transdermal patches may be associated with a lower risk of heart attack and FDA-approved products -- not compounded hormones -- may be associated with a slightly lower risk of stroke compared to synthetic hormones in pill form. "If confirmed by future randomized trials, these findings may be significant because for the past decade, many women who experienced severe menopause symptoms opted not to use hormone therapy because of the reported increased risk of stroke and heart attacks," said Chrisandra Shufelt, MD, director of the Women's Hormone and Menopause Program at the Barbra Streisand Women's Heart Center in the Cedars-Sinai Heart Institute. Shufelt said the study's findings are not conclusive and are based on observational follow-up, not a randomized clinical trial. Additionally, all types of hormone therapy had similar rates of total cardiovascular outcomes and all-cause mortality, the study showed. The similarities in results across formulations were greater than the … Continue reading

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