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Stem cell finding gives cancer hope

Posted: Published on August 11th, 2013

Stem cell technology can be used to mass-produce cancer-killing immune cells designed to target different kinds of tumour, scientists have shown. The research opens up the prospect of immunotherapy treatments helping many more cancer patients in the future. In theory cancer can be tackled by elements of the body's own immune defences, especially white blood cells called T-cells. But in practice, T-cells that target and kill cancer cells while ignoring healthy cells are very rare, and progress towards immune-based cancer treatments has been limited. The new approach provides a way to reprogramme T-cells and create large numbers of them "off the shelf" primed to attack specific cancers. A small number of healthy human T-cells were first reprogrammed into malleable stem cells with embryonic properties, US scientists reported in the journal Nature Biotechnology. These induced pluripotent stem cells (iPScs) were then engineered to produce a tumour-specific receptor molecule on their surfaces. Finally, the stem cells were coaxed to re-acquire their original T-cell properties while expanding to large numbers. Each of the T-cells now had the all-important receptor that allowed it to target a particular cancer "antigen" or protein, in this case lymphoma. Injected into mice with a human form of lymphoma, … Continue reading

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Genetic birth defects may lead to childhood cancer

Posted: Published on August 11th, 2013

Washington, Aug 11 (IANS) Children born with genetic birth defects like Down's syndrome are at an increased risk of developing childhood cancer, says a study. Scientists have said that children born with non-chromosomal birth defects have a two-fold higher risk of cancer before age 15, compared to children born without birth defects. However, cancer risk varies by the specific type of birth defect, and is not significantly increased in many of the more common birth defects, Science Daily reported citing the study published in July in PLOS ONE. Birth defects are an increasing health concern worldwide, and in 2010 the World Health Organisation identified birth defect prevention and care as a global priority. "There is a large body of evidence for increased cancer risk in children with Down's syndrome, a genetic birth defect caused by the presence of an extra copy of chromosome 21," says Lorenzo Botto, professor of paediatrics at the University of Utah School of Medicine and an author of the study. "However, studies to date have provided inconsistent findings on cancer risk in children with structural birth defects that are not caused by chromosome abnormalities." Excerpt from: Genetic birth defects may lead to childhood cancer … Continue reading

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New patterns found in the genetic relationship of 5 major psychiatric disorders

Posted: Published on August 11th, 2013

Public release date: 11-Aug-2013 [ | E-mail | Share ] Contact: Eric Peters petersem@vcu.edu 804-828-0563 Virginia Commonwealth University An international consortium has shown for the first time evidence of substantial overlap of genetic risk factors shared between bipolar disorder, major depressive disorder and schizophrenia and less overlap between those conditions and autism and attention deficit-hyperactivity disorder (ADHD), according to a study published this week in Nature Genetics' Advance Online publication. The root cause of psychiatric illnesses such as bipolar disorder, major depressive disorder schizophrenia, autism and ADHD is not fully understood. For more than 125 years, clinicians have based diagnosis on a collection of symptoms observed in patients. But, scientists have since identified that the five psychiatric disorders share a common genetic link and are now moving toward understanding the molecular underpinnings of psychiatric illness. The precise degree to which these disorders share common ground has remained unknown, until now. The project is led by the Cross-Disorder Group of the Psychiatric Genomics Consortium and is the largest genetic study of psychiatric illness to date. The findings provide insight into the biological pathways that may predispose an individual to disease and could ultimately lead to the development of new therapeutic avenues … Continue reading

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Better than STEM-CELL THERAPY, be healthier and become six (6) years younger using 4LIFE – Video

Posted: Published on August 11th, 2013

Better than STEM-CELL THERAPY, be healthier and become six (6) years younger using 4LIFE Become 6 years younger using 4LIFE Contact FAYE 09999271383 Transfer factors are smart cells that keep your immune system working properly. Without a proper ... By: Homebased Business … Continue reading

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Wake Forest researchers study urine as source for stem cells

Posted: Published on August 11th, 2013

WINSTON-SALEM, N.C. A daily bodily function urinating may become another option for collecting stem cells that can be transformed into regenerated tissue and organs. Researchers with the Wake Forest Institute of Regenerative Medicine have identified stem cells in urine that can become multiple cell types. Their report is available on the website of the journal Stem Cells. In a separate study released July 30, a group of researchers from the Guangzhou Institutes of Biomedicine and Health said they have been able to generate in mice tooth-like structures from urine-induced pluripotent stem cells. Dr. Anthony Atala, director of the Wake Forest institute, said the use of urine-derived stem cells to regenerate human tissue and organs remains several years away. Weve been looking at urine as a stem cell option since 2006, Atala said. Research has been so far, so good in rodents. Being able to use a patients own stem cells for therapy is considered advantageous because they do not induce immune responses or rejection. However, because tissue-specific cells are a very small subpopulation of cells, they can be difficult to isolate from organs and tissues. The challenge has been getting the right cells and the right results every time, Atala … Continue reading

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Stem-cell treatment not a cure-all, charging patients for clinical study unethical – 21 doc groups

Posted: Published on August 11th, 2013

By: Jet Villa, InterAksyon.com August 11, 2013 8:10 AM REUTERS FILE PHOTO InterAksyon.com The online news portal of TV5 MANILA - Twenty-one medical organizations have already signed a position statement, calling for stricter regulations of stem cell products and physicians doing the transplant. These are the: Philippine College of Physicians, Philippine College of Geriatric Medicine, Philippine Society of Allergy, Asthma and Immunology, Philippine Society of Hematology and Blood Transfusion, Philippine Society of Nephrology, Philippine Neurological Society, Philippine Society of General Surgeons, Philippine College of Surgeons, Philippine Heart Association, Philippine Society of Endocrinology and Metabolism, Philippine Society of Medical Oncology, Diabetes Philippines, Philippine Society of General Medicine, Philippine Society for Vascular Surgery, Philippine College of Chest Physicians, Philippine Rheumatology Association, Philippine Society of Gastroenterology, Philippine Society for Microbiology and Infectious Diseases, Philippine Academy of Rehabilitation Medicine, Philippine Society of Nuclear Medicine, and Academy of Filipino Neurosurgeons. The groups have called on the Department of Health and the Food and Drug Administration to issue clearer regulations for stem cell therapy for practicing clinicians to safeguard the health of Filipinos. Stem cell therapy for unproven indications is proliferating in the Philippines and posing serious safety issues to unknowing clients, they said. (We are) … Continue reading

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Looking for a cure with stem cells

Posted: Published on August 11th, 2013

Medical science has progressed by leaps and bounds with the advent of stem cell therapy. Stem cell is a generic cell that has the potential to become many types of specialised cells for the treatment of a wide range of diseases. In stem cell treatment, the damaged tissues of the diseased part are replaced by new adult cells. Stem cells have the potential to divide and grow into multiple tissues and regenerate natural organs. Stem cell therapy is the new realm of regenerative medicine for Diabetes Type 1, wound healing, Parkinson's, spinal cord injury, MI, MS, and many other terminal conditions. Who can become a Stem Cell Therapist? From a chief scientific officer to a lab assistant, opportunities are many for medical and non-medical students. There is a prevalent misconception that only medical professionals can become a stem cell therapist. In fact, stem cells cover a lot of ground, from molecular biology and biotechnology to cell transplantation and therapy. It means that people can come into stem cell biology from more or less any field. Candidates skilled in imaging are also eligible to become stem cells researchers or therapists. As there is always need for more tools, an electrical engineer … Continue reading

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India stem cell transplant – Video

Posted: Published on August 11th, 2013

India stem cell transplant Melinda beattie. By: Minreiny Beattie … Continue reading

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Stem Cell Therapy Treatment for Transverse Myelitis by Dr Alok Sharma, Mumbai, India. – Video

Posted: Published on August 11th, 2013

Stem Cell Therapy Treatment for Transverse Myelitis by Dr Alok Sharma, Mumbai, India. Improvement seen after Stem Cell Therapy Treatment for Transverse Myelitis by Dr Alok Sharma, Mumbai, India. After Stem Cell Therapy PT assessment: Objectively : 1) Grade 3-4 spasticity in... By: Neurogen Brain and Spine Institute … Continue reading

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Stem Cell Therapy Treatment for Stroke by Dr Alok Sharma, Mumbai, India. – Video

Posted: Published on August 11th, 2013

Stem Cell Therapy Treatment for Stroke by Dr Alok Sharma, Mumbai, India. Improvement seen in just 5 day after Stem Cell Therapy Treatment for Stroke by Dr Alok Sharma, Mumbai, India. After Stem Cell Therapy 1. Voluntary control of... By: Neurogen Brain and Spine Institute … Continue reading

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