Public release date: 2-Aug-2013 [ | E-mail | Share ] Contact: Press Office presse@iqwig.de 49-022-135-6850 Institute for Quality and Efficiency in Health Care The clot-inhibiting drug apixaban (trade name: Eliquis) has been approved in Germany since November 2012 for the prevention of embolism and stroke in adults with non-valvular atrial fibrillation. In an early benefit assessment pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined the added benefit of apixaban. IQWiG found an indication of a considerable added benefit of apixaban for each of two patient groups: Patients who can also be treated with a vitamin K antagonist (VKA) have a lower risk of dying, stroke or major bleeding than with warfarin treatment. This only applies to people older than 65 years, however. For younger patients, apixaban does not have an advantage. In patients for whom VKA is not an option, stroke and embolism occur less frequently than with acetylsalicylic acid (ASA). The G-BA distinguishes between two treatment situations Atrial fibrillation that is not caused by a leaking heart valve is referred to as "non-valvular atrial fibrillation". Apixaban is an option for patients … Continue reading
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