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Concerns as opening of stroke unit delayed again

Posted: Published on July 24th, 2013

Concerns as opening of stroke unit delayed again Tuesday, July 23, 2013 By Brendan Furlong and Fiachra Cionnaith A stroke unit due to open in Cork last month after two years of delays will remain closed until at least September. Dr ine Carroll, HSE national director of clinical strategy and programmes, told the Joint Oireachtas Health Committee in May that the unit would be open last month. However, the introduction of a temporary day surgical unit at the hospital, and claims of inadequate staffing levels, have caused yet more delays to the opening of the stroke unit. The opening of the facility, which will eventually work in tandem with another unit at the Mercy University Hospital in Cork City, was to bring to nine the number of units set up via the HSE National Stroke Programme. The HSE aimed to establish units in Dublin, the midlands, the north east, the south east, the west, Cork, and Limerick. The HSEs joint national clinical lead for stroke, Prof Joe Harbison, said the opening of the CUH unit had been slower than aimed for because of the temporary day surgical unit. However, it is understood inadequate staffing, technical and data protection issues have … Continue reading →

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XenoPort Announces Inclusion of Horizant (Gabapentin Enacarbil) in Guidelines for Long-Term Treatment of Restless Legs …

Posted: Published on July 24th, 2013

SANTA CLARA, Calif.--(BUSINESS WIRE)-- XenoPort, Inc. (XNPT) announced today the inclusion of gabapentin enacarbil, the active ingredient in Horizant (gabapentin enacarbil) Extended-Release Tablets, as a first-line therapy in new treatment guidelines created by the Task Force of the International Restless Legs Syndrome Study Group (IRLSSG). The manuscript, published in the current issue of Sleep Medicine, provides information for physicians determining treatment choices for restless legs syndrome/Willis-Ekbom Disease (RLS/WED) based on the long-term benefits and risks of each major class of medications. Horizant is the only non-dopamine agonist and the only alpha-2-delta ligand approved by the U.S. Food and Drug Administration (FDA) for the treatment of moderate-to-severe primary restless legs syndrome in adults. The last few years have seen tremendous advances in our knowledge of both the etiology of RLS/WED and its effective treatment, stated Diego Garcia-Borreguero, M.D., Chair, International Restless Legs Study Group and Director, Sleep Research Institute, Madrid, Spain. These guidelines are an important tool for guiding physicians in the choice for pharmacotherapy of patients requiring long-term treatment of RLS/WED symptoms. The guidelines state that either dopamine-receptor agonists or the alpha-2-delta ligands, which include gabapentin enacarbil, are the first-line treatment for patients with RLS/WED, and that the choice of … Continue reading →

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Italian doctor to present research on Irish set dancing as remedy for Parkinson's

Posted: Published on July 24th, 2013

By JANE WALSH, IrishCentral Staff Writer Published Tuesday, July 23, 2013, 7:21 AM Updated Tuesday, July 23, 2013, 9:41 AM Italian Doctor Daniel Volpe has discovered that Irish dancing has a positive effect on patients suffering from Parkinson's disease Photo by ParkinsonsItalia.it An Italian Doctors chance discovery of the therapeutic effects of Irish set dancing in the treatment of Parkinson's disease will be the subject of an international Gathering event in Co. Clare next month. Dr Daniel Volpe who is the Director of Neurological Rehabilitation at St. Raffaele Arcangelo Hospital in Venice will present his research work confirming the benefits of set dancing in the rehabilitative therapy for people with Parkinson's disease. As part of the 26th Annual International Traditional Music Festival in Feakle, the Italian neurologist will present his latest research on "The Therapeutic Effects of Irish Set Dancing in the Treatment of Parkinson's Disease." The Conference will feature a series of lectures, workshops, set dancing, sean-ns dancing and a Cil. Original post: Italian doctor to present research on Irish set dancing as remedy for Parkinson's … Continue reading →

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A new player in brain disease and stroke

Posted: Published on July 24th, 2013

Public release date: 23-Jul-2013 [ | E-mail | Share ] Contact: Eleanor Howell press@f1000.com 44-020-763-19129 Faculty of 1000 In degenerative brain diseases and after stroke, nerve cells die while their support cells activate the brain's immune system to cause further damage. Now Jonathan Gilthorpe, Adrian Pini and Andrew Lumsden at the MRC Centre for Developmental Neurobiology at King's College London, have found that a single protein, histone H1, causes these distinct outcomes. The research passed peer review within a week of being published in F1000Research, where Jan-Marino Ramirez, of the University of Washington, called the work "a very important contribution to our understanding of neurodegenerative disease and the response of the brain to injury" in his public referee report. He also noted that he is "confident that this study will be a much cited contribution to the field of traumatic brain injury". The most unexpected finding in this study is that a histone protein is responsible for neuronal damage. "Histone H1 partners with DNA in the cell nucleus and has been thought of as harmless," explain the authors, "The surprise came when we discovered that it can be released from brain cells upon injury, killing healthy nerve cells and activating … Continue reading →

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How to prolong remission of Multiple Sclerosis – Video

Posted: Published on July 24th, 2013

How to prolong remission of Multiple Sclerosis How to prolong remission of Multiple Sclerosis Multiple sclerosis (MS) is a chronic viral infection of Schwann cells and oligodendrocytes. I intend here to o... By: Gershom Zajicek M.D, … Continue reading →

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'MS wonder drug has given me a second chance at life…'

Posted: Published on July 24th, 2013

MULTIPLE sclerosis sufferer Kerry Lovatt says she has been given a second chance at life after becoming only the 76th person in the country to be prescribed a 1,400-a-month drug. The 32-year-old was diagnosed with the condition after suffering poor balance and blurred vision in September 2009. Kerry Lovatt with her friend Stewart Jepson. Picture: Ben Warburton Doctors initially thought Kerry, of Hampshire Crescent, Lightwood, had shingles after one side of her face went numb. Kerry, an assistant manager at Bon Marche, said: "First of all I had problems with my ears, they were over sensitive and I couldn't bear to hear running water or the TV. My vision went and I struggled to pick things up. Then things started to get worse. I had funny sensations down the left side of my body, I couldn't walk and I was being sick all of the time. It was really scary because no one knew what was up with me." We are more than just TV specialists Panasonic Fridge Freezers really are cool and we have an offer to SAVE 250 with a scoop buy ONLY 399 delivered fast and free plus we will collect the old one Terms: Offer while … Continue reading →

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Cannabis constituent has no effect on MS progression, study shows

Posted: Published on July 24th, 2013

Public release date: 23-Jul-2013 [ | E-mail | Share ] Contact: Andrew Gould andrew.gould@plymouth.ac.uk University of Plymouth The first large non-commercial clinical study to investigate whether the main active constituent of cannabis (tetrahydrocannabinol or THC) is effective in slowing the course of progressive multiple sclerosis (MS), shows that there is no evidence to suggest this; although benefits were noted for those at the lower end of the disability scale. The study is published in The Lancet Neurology. The CUPID (Cannabinoid Use in Progressive Inflammatory brain Disease) study was carried out by researchers from Plymouth University Peninsula Schools of Medicine and Dentistry. The study was funded by the Medical Research Council (MRC), the Multiple Sclerosis Society and the Multiple Sclerosis Trust, and managed by the National Institute for Health Research (NIHR) on behalf of the MRC-NIHR partnership. CUPID enrolled nearly 500 people with MS from 27 centres around the UK, and has taken eight years to complete. People with progressive MS were randomised to receive either THC capsules or identical placebo capsules for three years, and were carefully followed to see how their MS changed over this period. The two main outcomes of the trial were a disability scale administered by … Continue reading →

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Speech 1010- Persuasive Speech- Stem Cell Research – Video

Posted: Published on July 24th, 2013

Speech 1010- Persuasive Speech- Stem Cell Research Angad SPeech. By: MrAngaddeep … Continue reading →

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Stricter standards sought to curb stem-cell confusion

Posted: Published on July 24th, 2013

The exact nature and properties of mesenchymal stem cells remain unclear. STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY Pamela Robey is used to being sent samples by scientists who are anxious to know whether the mesenchymal stem cells (MSCs) they have extracted from fat can be coaxed to turn into either bone or cartilage. Robey, who directs the Stem Cell Unit at the US National Institutes of Health (NIH), is also used to delivering bad news to many of those who seek her help. They usually are not happy, she says, when her attempts to differentiate the cells produce little more than fatty globules. To Robey, that disappointment reflects a pervasive misunderstanding about what MSCs are and what they can do one that is fuelled by a lack of information. MSCs have been proposed as treatments for a wide range of ailments including heart and brain injury, joint damage, Crohns disease and multiple sclerosis. But some scientists say that these clinical aspirations have far outrun the basic science. It always seems a little bit like hocus pocus when youre treating everything from skeletal to immunological disorders, says George Daley, director of the Stem Cell Transplantation Program at Boston Childrens Hospital in Massachusetts. An … Continue reading →

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UC Davis Stem Cell Study Uncovers the Brain-Protective Powers of Astrocytes

Posted: Published on July 24th, 2013

SACRAMENTO, Calif. (PRWEB) July 23, 2013 One of regenerative medicines greatest goals is to develop new treatments for stroke. So far, stem cell research for the disease has focused on developing therapeutic neurons the primary movers of electrical impulses in the brain to repair tissue damaged when oxygen to the brain is limited by a blood clot or break in a vessel. New UC Davis research, however, shows that other cells may be better suited for the task. Published today in the journal Nature Communications, the large, collaborative study found that astrocytes neural cells that transport key nutrients and form the blood-brain barrier can protect brain tissue and reduce disability due to stroke and other ischemic brain disorders. "Astrocytes are often considered just housekeeping cells because of their supportive roles to neurons, but theyre actually much more sophisticated," said Wenbin Deng, associate professor of biochemistry and molecular medicine at UC Davis and senior author of the study. "They are critical to several brain functions and are believed to protect neurons from injury and death. They are not excitable cells like neurons and are easier to harness. We wanted to explore their potential in treating neurological disorders, beginning with stroke." Deng … Continue reading →

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