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Staying slim at menopause (2)

Posted: Published on July 2nd, 2013

Oladapo Ashiru | credits: File copy Contd. from last week Androgen: This hormone is responsible for sending your new weight directly to your mid section. In fact, weight gain during menopausal years is often known as mid age spread because of the rapid growth of the mid-section. Often, one of the first signs of menopause is an increased level of androgen in your body, which causes you to gain weight around your abdomen instead of around your lower half. Testosterone: helps your body to create lean muscle mass out of the calories that you take in. Muscle cells burn more calories than fat cells do, thereby increasing your metabolism. In natural menopause, levels of testosterone drop, resulting in the loss of muscle. Unfortunately, this means a lower metabolism rate. The lower your metabolism is, the slower your body burns calories. Hormone replacement There are some misconceptions about hormone replacement therapy that, if followed, can make you gain weight during menopause. The first misconception is that decreased estrogen levels is the main reason for many of the uncomfortable symptoms of menopause, such as hot flushes, sweating and mood swings, to mention but a few. We now know that the deficiency in … Continue reading →

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HRT ups risk of ‘brain tumour in women’ by 30pc

Posted: Published on July 2nd, 2013

London, July 02 : Women, who use hormone replacement therapy (HRT), are at a 30 per cent higher risk of developing brain tumours, a study has revealed. The research, conducted by the Danish Cancer Research Centre, found that the longer a woman is on the treatment, the higher is the risk, the Sun reported. Those who used HRT for ten years or more, had a 70 per cent chance of getting a tumour. The research, which explains why meningioma- the most common brain tumour -is found more frequently in women, also talks about why cases have risen in recent years. According to the research centre, long-term HRT use, particularly of combined oestrogen-progestogen, may increase the risk of meningioma. Women with meningioma also have a higher risk of breast cancer. It was found that about 85 per cent of meningiomas are benign but the tumours still cause symptoms including headaches, seizures, loss of balance and hearing loss. Excerpt from: HRT ups risk of 'brain tumour in women' by 30pc … Continue reading →

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Genome Institute of Singapore Scientists Discover Molecular Communication Network in Human Stem Cells

Posted: Published on July 2nd, 2013

Singapore, July 2, 2013 - (ACN Newswire) - Scientists at A*STAR's Genome Institute of Singapore (GIS) and the Max Planck Institute for Molecular Genetics (MPIMG) in Berlin (Germany) have discovered a molecular network in human embryonic stem cells (hESCs) that integrates cell communication signals to keep the cell in its stem cell state. These findings were reported in the June 2013 issue of Molecular Cell. Human embryonic stem cells have the remarkable property that they can form all human cell types. Scientists around the world study these cells to be able to use them for medical applications in the future. Many factors are required for stem cells to keep their special state, amongst others the use of cell communication pathways. Cell communication is of key importance in multicellular organisms. For example, the coordinated development of tissues in the embryo to become any specific organ requires that cells receive signals and respond accordingly. If there are errors in the signals, the cell will respond differently, possibly leading to diseases such as cancer. The communication signals which are used in hESCs activate a chain of reactions (called the extracellular regulated kinase (ERK) pathway) within each cell, causing the cell to respond by … Continue reading →

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ResearchMoz.us: Stem Cells Market (Adult, Human Embryonic, Induced Pluripotent, Rat-Neural, Umbilical Cord, Cell …

Posted: Published on July 2nd, 2013

ALBANY, New York, July 1, 2013 /PRNewswire/ -- New Report Added in ResearchMoz Reports Database Stem Cells Market (Adult, Human Embryonic, Induced Pluripotent, Rat-Neural, Umbilical Cord, Cell Production, Cell Acquisition, Expansion, Sub-Culture) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2012-2018 ResearchMoz announces that it has published a new study Stem Cells Market (Adult, Human Embryonic, Induced Pluripotent, Rat-Neural, Umbilical Cord, Cell Production, Cell Acquisition, Expansion, Sub-Culture) Stem cells are undifferentiated cells which are capable of differentiating into any type of cell that make-up the human body and thus, are capable of producing non-regenerative cells such as neural and myocardial cells. This report estimates the market for global stem cells in terms of revenue (USD billion) for the period 2012 - 2018, keeping 2011 as the base year. The global stem cells market is mainly segmented into four major sub-types namely market by products, market by technology, market by applications and market by geography. To Browse Full TOC, Tables & Figures visit:http://www.researchmoz.us/stem-cells-market-adult-human-embryonic-induced-pluripotent-rat-neural-umbilical-cord-cell-production-cell-acquisition-expansion-sub-culture-global-industry-analysis-size-share-growth-trends-and-forecast-2012-2018-report.html The market by products is segmented into three sub-types, namely adult stem cells, human embryonic stem cells and other type of stem cells. Adult stem cells are further segmented into hematopoietic stem cells, mesenchymal stem cells, … Continue reading →

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Vitamin C Influences Gene Activity In Stem Cells

Posted: Published on July 2nd, 2013

Featured Article Academic Journal Main Category: Stem Cell Research Also Included In: Nutrition / Diet;Fertility;Cancer / Oncology Article Date: 02 Jul 2013 - 3:00 PDT Current ratings for: Vitamin C Influences Gene Activity In Stem Cells 5 (2 votes) Senior author and stem-cell scientist Miguel Ramalho-Santos of the University of California San Francisco (UCSF) and colleagues write about their findings in a June 30th online issue of Nature. In cells, not all genes are active all the time. There is a regulated pattern of gene expression that switches genes on and off. This is held in the epigenome, the set of instructions that get passed on with DNA about how to control the DNA. One of the mechanisms the epigenome uses to regulate gene expression is DNA methylation. In DNA methylation, the epigenome adds a methyl group to a selected point on the genome to stop certain genes from being expressed. What Ramalho-Santos and colleagues discovered is that vitamin C plays a crucial role in helping to release the brakes that stop certain genes from being expressed in stem cells in embryos soon after fertilization when the sperm fuses with the egg. The team came across the result while comparing … Continue reading →

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Scientists In Singapore, Germany Discover Network In Human Stem Cells

Posted: Published on July 2nd, 2013

SINGAPORE, July 2 (Bernama) -- Scientists in Singapore and Germany have discovered a molecular network in human embryonic stem cells (hESCs) that integrates cell communication signals to keep the cell in its stem cell state. In a statement, A*STAR's Genome Institute of Singapore (GIS) said these findings by the institute and the Max Planck Institute for Molecular Genetics (MPIMG) in Berlin, were reported in the June 2013 issue of Molecular Cell. Many factors are required for stem cells to keep their special state, among others is the use of cell communication pathways. Cell communication is of key importance in multicellular organisms, such as the coordinated development of tissues in the embryo so that cells receive signals and respond accordingly. If there are errors in the signals, the cell will respond differently, possibly leading to diseases such as cancer. The communication signals which are used in hESCs activate a chain of reactions (called the extracellular regulated kinase (ERK) pathway) within each cell, causing the cell to respond by activating genetic information. The authors propose a model that integrates this bi-directional control to keep the cell in the stem cell state. These findings are particularly relevant for stem cell research, but they … Continue reading →

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Parkinson’s Treatment With Pluripotent Stem Cell-Derived Neurons Shows Promise

Posted: Published on July 2nd, 2013

Editor's Choice Academic Journal Main Category: Parkinson's Disease Also Included In: Stem Cell Research Article Date: 01 Jul 2013 - 0:00 PDT Current ratings for: Parkinson's Treatment With Pluripotent Stem Cell-Derived Neurons Shows Promise 3 (2 votes) The study - "Survival and Integration of Neurons Derived from Human Embryonic Stem Cells in MPTP Lesioned Primates" - has been published in the journal Cell Transplantation. Dr. D. Eugene Redmond, Yale University School of Medicine, said "Parkinson's disease was one of the first neurological disorders to be studied for potential replacement of lost neurons. Since the 1970s there has been significant progress with learning the required gene expression, growth factors and culture conditions for differentiating cells into apparent dopamine neurons." However, the authors explained that there have been disappointing results when transplanting dopamine neurons into rodents or monkeys - they did not become long-lasting midbrain specific neurons. They added that "there have only been pilot reports of functional improvement". In this study, the scientists assessed the long-term survival of apparent dopamine neurons in monkeys modeled with Parkinson's-like symptoms. They also tested the functional benefit of the new neurons. The authors found, as in previous studies, that gene expression of TH (tyrosine hydroxylase) … Continue reading →

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Varsity adds to research on asthma

Posted: Published on July 2nd, 2013

Bob Hancox. Genetic risk assessments could eventually also be used to predict which children with asthma were likely to grow out of the condition, and which would continue having symptoms as they grew older, the research suggested. The study's lead author is Dr Daniel Belsky, of the Duke University Medical Centre, in North Carolina, in the United States, and one of the Otago authors is Associate Prof Bob Hancox, a respiratory physician in the Otago preventive and social medicine department. Prof Hancox said the results were ''interesting'' from a scientific viewpoint but, like all good research, also raised many questions. ''There's a lot more to find out.'' It was ''early days'', a great deal more research had to be done, and it was much too early to apply the research to the clinical management of individual patients. The research again high-lighted the international importance of the long-running Dunedin multidisciplinary study of about 1000 children born in 1972-73, he said. A team of Otago and Duke University researchers set out to test how genetic discoveries concerning asthma predisposition related to the developmental and biological characteristics of the condition. Their findings were published last month in the online edition of the United … Continue reading →

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Giving hope: The promise of stem cell therapy – Video

Posted: Published on July 2nd, 2013

Giving hope: The promise of stem cell therapy MANILA - As stem cell treatment begins to gain traction among Filipinos, a surgeon believes the country is now entering a new phase in medicine. By: TheABSCBNNews … Continue reading →

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Type 2 Diabetes Patients Benefit From Bone Marrow Stem Cell Transplants

Posted: Published on July 2nd, 2013

Editor's Choice Academic Journal Main Category: Diabetes Also Included In: Stem Cell Research;Transplants / Organ Donations Article Date: 01 Jul 2013 - 0:00 PDT Current ratings for: Type 2 Diabetes Patients Benefit From Bone Marrow Stem Cell Transplants The research, published in Cell Transplantation, was carried out in India and looked at the safety and efficacy of autologous transplanted bone marrow stem cells in patients with type 2 diabetes (TD2M). Study corresponding author Anil Bhansali, PhD, professor and head of the Endocrinology Department at the Post Graduate Institute of Medical Education in Chandrigarh, India, said: Although there is an increasing interest in using stem cell transplantation to treat people with this condition, there has been little research observing the benefit of bone marrow-derived stem cells. "By experimenting with bone marrow-derived stem cells, the researchers sought to exploit the rich source of stem cells in bone marrow," the researchers said. The experts wanted to examine the efficacy and safety of autologous bone marrow-derived stem cell transplantation in patients with T2DM and who also had good glycemic control. Good glycemic control appeared as a critical factor in the transplantation group and in the non-transplanted control group. Cell transplantation had a considerable influence … Continue reading →

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