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Stem-cell hope for spinal patients as big test nears

Posted: Published on June 29th, 2013

Thursday, June 27, 2013 A leading researcher into severe spinal cord injuries says trials for stem-cell therapy show groundbreaking results in helping immobile patients to walk again. After progress in a second round of tests using stem cells to regrow nerve fibers, the China Spinal Cord Injury Network, set up in Hong Kong, has applied for regulatory approval in the mainland for a third and final phase, which could start in the autumn. "This will convince the doctors of the world that they do not need to tell patients `you will never walk again,"' said US- based doctor Wise Young, the alliance's chief executive. "Hong Kong is going to be way ahead of all countries if the spinal cord injury trial turns out to be positive. He said 15 of 20 patients in Kunming who received umbilical cord blood cell transplants and intensive therapy were on average able to walk with minimal assistance seven years after suffering complete spinal cord injury. "It's the first time in human history that we can see the regeneration of the spinal cord," Young added. The treatment involves injecting umbilical cord blood mononuclear cells into patients' spines to help regenerate nerves, while lithium is used … Continue reading

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Doctor claims breakthrough in race for spinal 'cure'

Posted: Published on June 29th, 2013

A leading researcher into severe spinal cord injuries on Wednesday said trials for stem-cell therapy showed groundbreaking results in giving immobile patients the ability to walk again. After progress in a second round of tests using stem cells to regrow nerve fibres, the China Spinal Cord Injury Network (ChinaSCINet) has applied for regulatory approval in China for a third and final phase, which it hopes to start in the autumn. "This will convince the doctors of the world that they do not need to tell patients 'you will never walk again'," US-based doctor Wise Young, chief executive officer of ChinaSCINet, told AFP. He said that 15 out of 20 patients in the Chinese city of Kunming, who received umbilical cord blood cell transplants and intensive walking therapy, were on average able to walk with minimal assistance seven years after complete spinal cord injury. "It's the first time in human history that we can see the regeneration of the spinal cord," Young said. The treatment involves injecting umbilical cord blood mononuclear cells into patients' damaged spines to help regenerate nerves, while lithium is used to promote the growth of the nerve fibres. Each component of the combination therapy will be tested … Continue reading

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Stem cell therapy holds promise for eye disorders

Posted: Published on June 29th, 2013

Cell-based therapies are providing new hope for the treatment of sight-threatening inflammation. A review published in Progress in Retinal and Eye Research provides a comprehensive outline of current and future therapy for uveitis (also called intra-ocular inflammation). Uveitis is a group of conditions that account for a significant proportion of visual disability, characterised by progressive visual loss caused by retinal inflammation and oedema. The disorder is most common in people aged 2060, and the financial burden is as high as that of diabetic eye disease. Current treatment for uveitis includes the use of antibiotics, immunosuppressants, and oral steroids, however, they result in side-effects and none have been specifically approved for the treatment of uveitis (they have all been prescribed off label). Professor John Forrester from the Centre for Experimental Immunology, Lions Eye Institute, Perth says that there is a long list of side-effects caused by current treatment programs including renal failure, anaemia, and high blood pressure. In about 50 per cent of patients with uveitis, no infectious cause can be found and an immune-mediated or autoimmune cause is suspected. In these instances, pioneering cell-based therapies may provide the best hope for long-term treatment. Cell-based therapies can be divided into two … Continue reading

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VistaGen Provides Update on $36 Million Strategic Financing Agreement

Posted: Published on June 29th, 2013

SOUTH SAN FRANCISCO, CA--(Marketwired - Jun 28, 2013) - VistaGen Therapeutics, Inc. (OTCQB: VSTA), a biotechnology company applying pluripotent stem cell technology for drug rescue, predictive toxicology and drug metabolism assays, today announced an update on the status of its strategic financing agreement with Autilion AG. Under the terms of the parties' April 2013 agreement, as amended, Autilion AG has committed to invest $36 million in VistaGen in consideration for 72 million shares of restricted VistaGen common stock, at a price of $0.50 per share, in a series of closings ending on or before September 30, 2013. The parties have amended their agreement, completed a first closing and scheduled additional closings to occur in July, August and September 2013. As noted previously, the self-placed strategic financing does not include warrants or investment banking fees. Shawn K. Singh, VistaGen's Chief Executive Officer, stated, "I met with Autilion's team earlier this week, and we have been working closely with them since signing our agreement in April.We are confident and excited about completing this transformative financing.Building on the positive developments in our labs presented during the Annual Meetings of the Society of Toxicology and International Society of Stem Cell Research in March and … Continue reading

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April receiving stem cell treatment in Mexico – Video

Posted: Published on June 29th, 2013

April receiving stem cell treatment in Mexico April's US Dr. Lucinda Messer and friend Patty. By: april2dance … Continue reading

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House probe on stem cell treatments sought

Posted: Published on June 29th, 2013

MANILA -- A Visayan lawmaker sought a congressional inquiry Saturday parallel to the investigation conducted by medical groups on the stem cell treatments done in the country. Malacaang earlier warned the public against stem cell therapy following the recent incident involving a lawmaker who undergone the treatment but has experienced other health problems. Western Samar Representative Mel Senen Sarmiento sought for the inquiry following the deaths of two lawmakers which are linked to complications brought by the treatment. The late Bohol Representative Erico Aumentado and Pedro Romualdo of Camiguin supposedly died after undergoing the stem cell treatment overseas "I will definitely ask for a congressional inquiry, parallel to any other investigations by government agencies and independent medical groups. This concerns public safety. I am also concerned about reports of stem cell treatments being done in the country," Sarmiento said. It was reported that the Philippine Medical Association (PMA) and the Philippine Society for Stem Cell Medicine (PSSCM) is conducting an investigation as to the circumstances of the death of three politicians who went to Germany for the treatment. Dr. Leo Olarte, PMA's president and PSSCM's spokesperson refused to name the politicians pending the result of the investigation. The PMA and … Continue reading

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Palace cautions public on stem cell treatment

Posted: Published on June 29th, 2013

by Natashya Gutierrez Posted on 06/28/2013 7:43 PM |Updated 06/28/2013 8:13 PM SKIN REJUVENATION. One of the alleged benefits of stem cell treatment is skin rejuvenation, which helps make people look younger. Graphic by Teddy Pavon/Rappler MANILA, Philippines - Malacaang on Friday, June 28, warned Filipinos about seeking stem cell therapy from unaccredited practitioners, a treatment 3 lawmakers received before they died and which is now being investigated as possible cause of their deaths. Deputy Presidential Spokesperson Abigail Valte said the public should take precaution, since it's not the cure-all for illnesses. "The so-called cure all is fake. There is no treatment that will cure all of your ills, Valte told reporters in response to questions about stem cell treatments. She reiterated the Department of Health's (DOH) reminder to choose DOH-accredited hospitals for the treatment, warning clinics and hospitals that offer it without accreditation. Let me repeat, its the hospital that must be accredited, not the doctor. Not the individual. Those stand-alone clinics, they cannot get accreditation from the DOH. So that is our warning to our fellowmen, Valte said. According to Valte, hospitals must file for accreditation with the DOH by August 31 to continue offering the treatment. Earlier … Continue reading

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Philippines government to crack down on unaccredited stem cell treatment

Posted: Published on June 29th, 2013

Manila: The government is poised to launch a crackdown on establishments offering stem cell treatment without proper accreditation amid reports that at least two lawmakers had died after undergoing such medical procedure. Health Secretary Enrique Ona said a number of commercial establishments had mushroomed across the country offering stem cell therapy, however, only a few of these are properly accredited by the Department of Health. Reports quoted Ona as saying that patrons are putting their lives at risk by getting service from these practitioners instead of government accredited establishments. The crackdown on unlicensed clinics and hospitals providing these kind of medical services in the country came in the wake of reports that two lawmakers and a government executive had died after undergoing stem cell therapy. Article continues below According to Dr Leo Olarte, President of the Philippine Medical Association, the three had separately undergone stem cell therapy to cure their respective illnesses, particularly liver cancer, heart disease and pneumonia. The three were all senior aged. We were told that the two died one year after undergoing the medical procedures while the third passed away only recently, he said. At least one of the patients, received treatment from a doctor who … Continue reading

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Pluripotent stem cell-derived neurons may be a viable Parkinson's disease treatment

Posted: Published on June 29th, 2013

Public release date: 28-Jun-2013 [ | E-mail | Share ] Contact: Robert Miranda cogcomm@aol.com Cell Transplantation Center of Excellence for Aging and Brain Repair Putnam Valley, NY. (Jun. 28 2013) A team of researchers from Rush University, Yale University, the University of Colorado and the St. Kitts Biomedical Research Foundation transplanted human embryonic stem cells into primate laboratory animals modeled with Parkinson's disease and found "robust survival" of the cells after six weeks and indications that the cells were "well integrated" into the host animals. The study appears as an early e-publication for the journal Cell Transplantation, and is now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/pre-prints/ct1000wakeman. "Parkinson's disease was one of the first neurological disorders to be studied for potential replacement of lost neurons," said Dr. D. Eugene Redmond of Yale University School of Medicine. "Since the 1970s there has been significant progress with learning the required gene expression, growth factors and culture conditions for differentiating cells into apparent dopamine neurons." However, the researchers noted that transplanted dopamine neurons have not produced "long-lasting midbrain specific neurons when transplanted into rodents or monkeys" and there have only been pilot reports of functional improvement. According to the study authors, their study tested the … Continue reading

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Palace: 'Cure-all' stem cell therapies not true

Posted: Published on June 29th, 2013

MANILA - Hospitals in the Philippines offering stem cell treatment should be accredited by the Department of Health, Malacaang said Friday. Deputy presidential spokesperson Abigail Valte said hospitals must file the needed requirements for accreditation beginning August 31. The DOH will issue an administrative order regarding this in the wake of reports that three politicians died after undergoing the treatment abroad. Ang ina-accredit po ng DOH ay mga ospital para po doon sa mga ganitong treatment and come August 31, kailangan na pong mag-file ng mga ospital noong kanilang accreditation requirements for them to continue to offer this treatment, kung sakaling meron na po sila. So may accreditation process po yan, Valte said. She warned the public against individuals or clinics that claim they are authorized to conduct stem cell operations and those that claim they are capable of giving cure-all stem cell treatments. Uulitin po natin, yung ospital po yung ina-accredit hindi po yung doktor. Hindi po individual. Yung mga stand-alone clinic po, hindi po yan pwedeng magpa-accredit sa DOH so yun po yung isang warning po natin doon sa ating mga kababayan, Valte said. Isa pa pong interesting point, mula po sa DOH: Yung stem cell treatment daw … Continue reading

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