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Whole body vibration therapy increases bone strength

Posted: Published on June 18th, 2013

June 17, 2013 A treatment known as whole body vibration therapy significantly increases bone strength among adolescents with cerebral palsy, a new clinical trial from New Zealand shows. The results were presented Saturday at The Endocrine Society's 95th Annual Meeting in San Francisco. Cerebral palsy affects more than half a million people in the United States. Caused by brain damage around the time of birth, the disorder affects muscle tone and movement, which can severely decrease the quality of life by making walking and other daily activities difficult. As movement becomes impaired, disuse weakens both the muscles and bones. Although few therapies have proven successful at increasing bone and muscle strength among people with cerebral palsy, one promising approach is whole body vibration therapy, or WBVT. This method, as its name implies, involves standing on a machine that moves the body, causing a tilting movement of the pelvis similar to the motion of walking but much more frequently. Previous research among healthy adults, including post-menopausal women, has demonstrated that whole body vibration therapy can promote bone and muscle health. To see if these beneficial effects occur in adolescents with cerebral palsy, researchers measured bone-mineral density and muscle mass after a … Continue reading

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RSNA: Concussion Patients Show Alzheimer’s-like Brain Abnormalities

Posted: Published on June 18th, 2013

Oak Brook, IL (PRWEB) June 17, 2013 The distribution of white matter brain abnormalities in some patients after mild traumatic brain injury (MTBI) closely resembles that found in early Alzheimers dementia, according to a new study published online in the journal Radiology. Findings of MTBI bear a striking resemblance to those seen in early Alzheimers dementia, said the studys lead author, Saeed Fakhran, M.D., assistant professor of radiology in the Division of Neuroradiology at the University of Pittsburgh School of Medicine. Additional research may help further elucidate a link between these two disease processes. MTBI, or concussion, affects more than 1.7 million people in the United States annually. Despite the name, these injuries are by no means mild, with approximately 15 percent of concussion patients suffering persistent neurological symptoms. Sleep-wake disturbances are among the earliest findings of Alzheimers patients, and are also seen in a subset of MTBI patients, Dr. Fakhran said. Furthermore, after concussion, many patients have difficulty filtering out white noise and concentrating on the important sounds, making it hard for them to understand the world around them. Hearing problems are not only an independent risk factor for developing Alzheimers disease, but the same type of hearing problem … Continue reading

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Concussion patients show Alzheimer’s-like brain abnormalities

Posted: Published on June 18th, 2013

Public release date: 18-Jun-2013 [ | E-mail | Share ] Contact: Linda Brooks lbrooks@rsna.org 630-590-7762 Radiological Society of North America OAK BROOK, Ill. The distribution of white matter brain abnormalities in some patients after mild traumatic brain injury (MTBI) closely resembles that found in early Alzheimer's dementia, according to a new study published online in the journal Radiology. "Findings of MTBI bear a striking resemblance to those seen in early Alzheimer's dementia," said the study's lead author, Saeed Fakhran, M.D., assistant professor of radiology in the Division of Neuroradiology at the University of Pittsburgh School of Medicine. "Additional research may help further elucidate a link between these two disease processes." MTBI, or concussion, affects more than 1.7 million people in the United States annually. Despite the name, these injuries are by no means mild, with approximately 15 percent of concussion patients suffering persistent neurological symptoms. "Sleep-wake disturbances are among the earliest findings of Alzheimer's patients, and are also seen in a subset of MTBI patients," Dr. Fakhran said. "Furthermore, after concussion, many patients have difficulty filtering out white noise and concentrating on the important sounds, making it hard for them to understand the world around them. Hearing problems are not … Continue reading

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Chelmsford woman will ride to end MS

Posted: Published on June 18th, 2013

On June 29 and 30, Erin Hennessey, of Chelmsford, will join more than 2,200 people riding 150 miles by bicycle from UMass Boston to Provincetown during the 29th annual Bike MS: Cape Cod Getaway, presented by EMD Serono & Pfizer. Hennessey is one of a select group of about 50 riders who have MS. Diagnosed in 2011, she chose to ride and to raise funds to fuel cutting-edge research and treatments to stop progression, restore function, and end MS forever. This is her second Cape Cod Getaway. A member of the Peps Peddlers team, Hennessey is participating in the I Ride with MS campaign, sponsored by Genzyme, a Sanofi Company, which is committed to supporting the MS community through its MS One to One (www.msonetoone.com) program. She will wear a special cycling jersey during the ride that says, "I Ride with MS," which provides greater visibility for riders living with MS to everyone else on the ride. By personalizing the disease, all cyclists are more strongly connected to the movement, inspiring and empowering them to pedal a bit harder along their journeys. Organized by the National Multiple Sclerosis Society, Bike MS (www.bikeMS.org) consists of 100 cycling events across the country … Continue reading

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Intellect Neurosciences Engages Evli Corporate Finance to Explore Strategic Alternatives to Maximize Shareholder Value

Posted: Published on June 18th, 2013

NEW YORK, June 18, 2013 (GLOBE NEWSWIRE) -- Intellect Neurosciences, Inc. (ILNS), a biopharmaceutical company engaged in the discovery and development of treatments for the prevention and treatment of neurodegenerative diseases, announced today that its Board of Directors has engaged Evli Corporate Finance to assist the company with the exploration of strategic alternatives. The Board of Directors is undergoing a strategic review of the feasibility and relative merits of various financial strategies for the company, which may include partnerships, strategic business model alternatives, a sale or other transaction. Evli Corporate Finance is part of Evli Bank Plc, which is an independent investment and wealth management bank whose clients are institutions, companies and high net worth individuals. The Evli Group, with headquarters in Finland, has through its corporate finance operations significant experience in working with development companies in the pharma and medtech industries. Elliot Maza, a director of the company, commented, "We have selected Evli Corporate Finance for this strategic review because of Evli's extensive international relationships in the pharmaceutical industry. Several of our potential partners are based in Europe where Evli has deep and widespread relationships. Evli shares the Board of Directors' belief that the company's asset portfolio, which includes … Continue reading

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Stem cell discovery might someday help regrow lost fingers

Posted: Published on June 18th, 2013

The power of regeneration might be right at your fingertips Clumsy manicurists can thank a set of stem cells under the base of the fingernail for erasing their mistakes. Those cells allow not only trimmed fingernails but amputated fingertips to regrow. Doctors might one day use nail stem cells to treat malformed nails or even amputated limbs, according to research by Mayumi Ito of New York University Langone Medical Center. Scientists have long known that children and some adults can regrow the tips of their fingers after amputation. But digits cant regenerate if more than the nail region is amputated. Ito and her colleagues traced the fate of cells on the back feet of mice during nail growth and found a population of stem cells that produces the hard part of the nail and the soft tissue underneath. When the researchers cut off the end of a toe, signals from the regrowing nail stimulated the tissue underneath to form new bone, the authors reported in the journal Nature last week. The digit bones can regenerate only if the amputated stump still has some nail stem cells, the researchers found. But the cells alone are not enough; also crucial is a … Continue reading

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Opposing Sides Passionate Over Stem Cell Research Initiative

Posted: Published on June 18th, 2013

February 24, 2006 Nancy Hughson of Kirkwood is one of the 46,000 state residents who've joined Missouri Stem Cell Research and Cures Initiative. The group hopes to place a measure on the November ballot to protect such research from interference by state legislators. "I've joined and I look forward to seeing this on the state ballot," said Hughson. "My son had leukemia when he was a little boy, so I am very sensitive to the need for medical research for life-saving cures. "My son benefitted from research that had just resulted in some new, approved approaches for his illness," added Hughson. "I don't think we should allow roadblocks to be put up in front of research. I think we should encourage any research in the battle to defeat life-threatening diseases." Among the groups lining up against the cause of Missouri Stem Cell Research and Cures Initiative is Missouri Right to Life. Pam Fichter, a Warson Woods resident and the state president of Missouri Right to Life, said she opposes the initiative petition "because it seeks to place the right to clone and to kill in the state constitution." Fichter said her group is mounting an information campaign against the drive … Continue reading

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CollabRx to Collaborate With the University of Chicago Medical Center on Clinical Cancer Sequencing and Interpretation

Posted: Published on June 18th, 2013

SAN FRANCISCO, June 18, 2013 (GLOBE NEWSWIRE) -- CollabRx, Inc. (CLRX), a data analytics company focused on informing clinical decision making in molecular medicine, today announced a collaboration with the thoracic oncology program at the University of Chicago Medical Center, one of the nation's leading cancer treatment centers with innovative clinical and translational research programs in cancer genetics and therapeutics. The joint initiative will combine CollabRx content and technology resources with the results of genetic sequencing-based tests conducted at the University of Chicago Medical Center. The tests are designed to enable physicians to consider a tumor's unique genetic profile in cancer treatment planning. The collaboration will be led at the University of Chicago Medical Center by Ravi Salgia, MD, PhD, a professor of medicine and vice chair of translational research at the University of Chicago. "Our program is committed to identifying optimal treatments for cancer patients using a holistic approach," said Dr. Salgia. "This commitment includes consideration of drugs and other therapies that target genetic abnormalities in tumors. These genetic abnormalities can now be efficiently identified using cancer mutation panels based on next generation sequencing technologies. CollabRx's expert systems add substantial value to these panels by infusing interpretation and insight … Continue reading

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Genetic testing company should free data

Posted: Published on June 18th, 2013

Now that the Supreme Court has ruled that merely isolating a DNA sequence does not make it eligible to patent, the question arises, What will happen to the crucially important data accumulated by an overly broad monopoly? The answer to this question has implications for people who may have an inherited risk for breast and ovarian cancer and to the scientists who hope to use that data for life-saving decisions about cancer surgery. For the past 15 years, Myriad Genetics of Salt Lake City, Utah, has performed more than a million diagnostic tests for mutations in two genes -- BRCA1 and BRCA2 -- that are associated with inherited risk of breast and ovarian cancer. The Supreme Court ruling means Myriad has enjoyed a 15-year monopoly far broader than it should have been. The company now faces a fateful decision about what to do with that data it collected as a monopolist. Will Myriads data be kept as proprietary assets to give Myriad a leg up on the competition that has already arisen, with four companies announcing after the Courts decision they will introduce BRCA genetic testing? Or will Myriad share the data so others outside Myriad can know the basis … Continue reading

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Similar genetic variation found in overweight newborns and adults

Posted: Published on June 18th, 2013

Public release date: 18-Jun-2013 [ | E-mail | Share ] Contact: Aaron Lohr alohr@endocrine.org 240-482-1380 The Endocrine Society Similar genetic variations occur in both overweight newborns and obese adults, a large study finds. The results will be presented Tuesday at The Endocrine Society's 95th Annual Meeting in San Francisco. "Our data suggest that adult obesity and newborn adiposity share, in part, a common genetic background," said study lead author Reeti Chawla, MD, fellow in pediatric endocrinology at Ann & Robert H. Lurie Children's Hospital of Chicago and the Northwestern University Feinberg School of Medicine, in Chicago, IL. "Allowing earlier identification of high-risk newborns may allow for earlier interventions to take place to possibly prevent obesity later in life. " Obesity has become an epidemic worldwide. In the United States alone, more than one-third of adults are obese, according to the Centers for Disease Control and Prevention. Excess weight and obesity are related to numerous health problems, including heart disease, type 2 diabetes, stroke and some cancers. Since being obese in childhood increases the risk of adult obesity, medical researchers are interested in identifying early risk factors, or genetic markers, to help predict who is at greater risk for weight gain. … Continue reading

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