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Family hope AT Society research can save little Taunton schoolgirl Gracie

Posted: Published on June 12th, 2013

Family hope AT Society research can save little Taunton schoolgirl Gracie 1:00pm Tuesday 11th June 2013 in News By Phil Hill THE family of a seven-year-old girl with a rare time-bomb condition hope a research project could buy her more time. Gracie Potter will die young unless a cure is found for ataxia-telangiectasia, which has resulted in her needing a wheelchair and regular treatment. Her low immune system means even a cold is serious, while she nearly died from chickenpox, is at increased risk of cancer and can only walk short distances with a frame. Gracie, who attends Blackbrook Primary School, Taunton, needs haemoglobin pumped into her body weekly and regular antibiotics. Her mother, Sheryl, said: A-T severely shortens people's lives. If Gracie catches a cold, it's ten times worse and when she got chickenpox, the medicine gave her kidney failure and it was touch and go. A-T affects her chest and lungs which could kill her. We're living with a ticking time-bomb. She's unlikely to live much past her teens. Continue reading here: Family hope AT Society research can save little Taunton schoolgirl Gracie … Continue reading

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Ap Government Stem Cell Research – Video

Posted: Published on June 12th, 2013

Ap Government Stem Cell Research I created this video with the YouTube Video Editor (http://www.youtube.com/editor) By: Carly Roberts … Continue reading

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Stem Cell Primer Video – Video

Posted: Published on June 12th, 2013

Stem Cell Primer Video By: Dr. Max Gomez … Continue reading

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Novel Liver Stem Cell Model Could Speed Up Process for Developing New Drugs

Posted: Published on June 12th, 2013

Durham, NC (PRWEB) June 11, 2013 The path to bringing a new drug to market is, simply put, a rocky one. Not only is it estimated to take over 12 years at an average price tag running anywhere between US $800 million and US $2 billion, but more often than not the new drug never makes it through the process. But now a research team reports that it has developed a way to speed up the process. Their work, which involves the creation of a highly stable and sensitive liver stem cell model, is reported in the latest issue of STEM CELLS Translational Medicine. Liver toxicity is the second most common cause of human drug failure, explained David Hay, Ph.D., of the University of Edinburghs MRC Centre for Regenerative Medicine, who led the team made up of university colleagues and scientists from Bristol-Myers Squibb, Princeton, N.J. But one major bottleneck in safety testing new drugs has been finding a routine supply of good quality primary human hepatocytes from the desired genetic background. Scientists have long believed that finding an efficient way to force pluripotent stem cells (PSCs) to develop into hepatocytes liver cells could be the way around the problem. … Continue reading

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Thermo Fisher Scientific Expands Stem Cell Media Offerings with HyCell-STEM and HyCell-STEM-FF Systems

Posted: Published on June 12th, 2013

Yields optimized stem cell growth and expansion per passage to accelerate research and discovery BOSTON--(BUSINESS WIRE)--Thermo Fisher Scientific Inc., the world leader in serving science, today introduced the Thermo Scientific HyClone HyCell-STEM and HyCell-STEM-FF stem cell culture media, designed to optimize the expansion rate of human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) per passage for cell culture applications including cell signaling, drug discovery and therapeutic research. The new HyCell-STEM media solutions will be showcased this week at the 11thAnnual International Society for Stem Cell Research (ISSCR) conference at the Boston Convention and Exhibition Center, Booth #637. With the introduction of HyCell-STEM and HyCell-STEM-FF, we are offering researchers solutions that increase the rate of stem cell expansion while preserving cell morphology, stemness and pluripotency. Further, scientists may anticipate outstanding recovery after thaw, following cryopreservation of cells. There are exciting discoveries being made in the stem cell area today, and researchers demand the highest quality products to increase yields and integrity of their cell cultures, said Roberta Morris, business director for Thermo Fisher Scientific. With the introduction of HyCell-STEM and HyCell-STEM-FF, we are offering researchers solutions that increase the rate of stem cell expansion while preserving cell morphology, … Continue reading

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Stem cells reach standard for use in drug development

Posted: Published on June 12th, 2013

Public release date: 11-Jun-2013 [ | E-mail | Share ] Contact: Tara Womersley tara.womersley@ed.ac.uk 44-131-650-9836 University of Edinburgh Drug development for a range of conditions could be improved with stem cell technology that helps doctors predict the safety and the effectiveness of potential treatments. Medical Research Council scientists at the University of Edinburgh have been able to generate cells in the laboratory that reach the gold standard required by the pharmaceutical industry to test drug safety. The researchers used stem cell technology to generate liver cells which help our bodies to process drugs. They found that the cells were equally effective, reaching the same standard, as cells from human liver tissue currently used to assess drug safety. These human cells used in drug testing are in short supply and vary considerably due to different donors. As a result they are not an ideal source for drug development. The stem cell based technique developed in Edinburgh, addresses these issues by offering a renewable production of uniform liver cells in the laboratory. Dr David Hay of the Medical Research Council (MRC) Centre for Regenerative Medicine at the University of Edinburgh, said: "Differing genetic information plays a key role in how patients' livers … Continue reading

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Life Technologies Launches Industry’s First Stem Cell Characterization Panel

Posted: Published on June 12th, 2013

CARLSBAD, Calif., June 12, 2013 /PRNewswire/ --Life Technologies Corporation (LIFE) today launched the TaqMan hPSC Scorecard Panel, a first-of-its-kind characterization assay that establishes a standardized benchmark against which researchers can now evaluate pluripotency and trilineage differentiation potential in human embryonic (ES) and induced pluripotent stem (iPS) cell lines. Life will showcase the technology during the International Society for Stem Cell Research (ISSCR) conference in Boston June 12-15. Until now, scientists have evaluated pluripotency the potential for ES and iPS cells to differentiate into any cell type with laborious, costly and non-standardized methods that provide ambiguous results. Additionally, their inability to accurately determine cell lines' propensity to differentiate into one of the three primary cell germ layers has contributed to major hurdles that impede stem cell technology from moving into the clinic. The TaqMan hPSC Scorecard Panel, however, relies on a specific range of gene expression levels identified at Harvard University to accurately characterize cell lines in two critical areas: pluripotency and lineage bias. The panel is also being offered with cloud-based software for rapid data analysis and data sharing among research collaborators. "The rapid advancements in stem cell research over the last few years have created a need for more … Continue reading

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Companion Diagnostics and Other Aspects of Personalized Medicine

Posted: Published on June 12th, 2013

NEW YORK, June 11, 2013 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Companion Diagnostics and Other Aspects of Personalized Medicine http://www.reportlinker.com/p01277476/Companion-Diagnostics-and-Other-Aspects-of-Personalized-Medicine.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Therapy The focus of this report is the use of personalized medicine for pharmacological/diagnostic combinations; particularly pharmacological therapies and the diagnostic tests, which can provide information on the likelihood of a patient to respond to specific treatments. Historically, drugs have been developed on a "one-size-fits-all" basis, but due to patients responding differently to the same drug and having potentially life threatening side effects, new therapies have been developed for approaching the treatment of diseases. Such an approach is with personalized medicine. Personalized medicine is an all-encompassing term for focused treatments in diseases. While in some areas, personalized medicine may focus on an inpidual's genome in response to therapy, in others it may be broader and focus on tailoring a medical treatment to the characteristics of each patient. Often in the form of drug/diagnostic combinations, personalized medicine is commonly used in treating breast cancer. Such an example is using estrogen and progesterone receptors, which are biomarkers, in combination with immunochemistry tests to determine an appropriate therapy. Other methods of personalized medicine for breast … Continue reading

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Genetic studies lead to clinical trial of new treatment for type 1 diabetes

Posted: Published on June 12th, 2013

Public release date: 11-Jun-2013 [ | E-mail | Share ] Contact: Jen Middleton j.middleton@wellcome.ac.uk 44-207-611-7262 Wellcome Trust A clinical trial is underway for a potential new treatment for type 1 diabetes that could eventually mean patients are able to reduce insulin treatment from several times a day to only once or twice a week. The new treatment is a direct result of research to understand the genetics of the disease. Type 1 diabetes is the most common severe chronic autoimmune disease worldwide and the incidence of the disease is rising rapidly. It causes the immune system to mistake cells in the pancreas as harmful and attack them. When these cells are damaged the pancreas is unable to produce insulin, which plays an essential role in transferring glucose out of the bloodstream and into cells to be converted into energy. The management of type 1 diabetes usually involves measuring the amount of glucose in the blood and injecting artificial insulin to make up for the insulin the pancreas is not producing. Type 1 diabetes is known to be a genetically complex disease there is no single gene that causes the disease, but rather dozens of genes that increase the risk of … Continue reading

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Sequenom CMM Opens New CLIA Lab Facility In North Carolina

Posted: Published on June 12th, 2013

SAN DIEGO, June 12, 2013 /PRNewswire/ --Sequenom, Inc. (SQNM), a life sciences company providing innovative genetic analysis solutions, today announced that its wholly owned subsidiary, the Sequenom Center for Molecular Medicine (Sequenom CMM), has completed the build-out and validation of an additional laboratory location in Raleigh-Durham, NC, and is now processing patient samples commercially. This new laboratory location adds capacity and redundancy to the existing Sequenom CMM laboratory locations in California and Michigan. With an initial capacity of 100,000 tests per year, the North Carolina facility will primarily support processing of the MaterniT21 PLUS laboratory-developed test (LDT) and will immediately increase Sequenom CMM's total MaterniT21 PLUS testing capacity to over 300,000 test samples per year. This practice-changing prenatal LDT analyzes the relative amount of chromosome 21, 18, and 13, as well as X and Y material in cell-free fetal DNA obtained from a maternal blood sample as early as 10 weeks ofpregnancy. "We are excited about the opening in North Carolina of our third US-based laboratory location. Our investment in establishing this new presence on the East coast will allow us to better meet the needs of health care providers by providing critical additional capacity and geographic back-up needed to … Continue reading

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