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Chicken fingers chain coming to Tyler

Posted: Published on June 11th, 2013

TYLER (TYLER MORNING TELEGRAPH) - Raising Cane's Chicken Fingers is coming to Tyler. Raising Cane's USA, LLC, of Plano, filed a building permit to construct a new 2,715-square-foot dine-in fast food restaurant with drive-thru service at 4186 S. Broadway Ave. for $800,000. Work includes removing existing trees and paving, providing new grading, paving and landscaping and constructing the building. MAPP Construction, of Baton Rouge, La., is the contractor. The Tyler Independent School District is renovating the science labs at the two local high schools. Work includes gutting and redoing four labs at John Tyler High School, at 1120 NNW Loop 323, for $800,000; and gutting and redoing six lab rooms at Robert E. Lee High School, at 411 ESE Loop 323, for $1.2 million. WRL General Contractors Ltd., of Flint, is the contractor. Smith County is turning a 2,508-square-foot space at 308 E. Ferguson into an office for the Precinct 1 constable for $45,000. Mike Pile BMW is doing demolition work to its 23,199-square-foot facility at 2401 WSW Loop 323 for $30,000. Lay Construction is the agent and Vastida Systems, of Plano, is the contractor. TSR Construction Inc. is putting a new metal roof on a storage building at 1005 … Continue reading

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News Obituaries

Posted: Published on June 11th, 2013

Linda Vallesillo Linda Vallesillo, 72, passed away on May 4, 2013 at her home in Banning due to heart failure. She was a resident of Banning for over 60 years. She retired from the Banning School District and Christmas Store. She enjoyed gardening, camping, scrapbooking and spending time with her family. She was preceded in death by her husband, John Vallesillo of Banning and sisters, Nancy Golden of Long Beach and Janet Mitchell of San Bernardino. A memorial will be held June 15 at 11 a.m. at Weaver Mortuary in Beaumont with a reception to follow. Evelyn Kringen (Ilac) Evelyn Kringen (Ilac), 65, departed this life and went to her eternal heavenly home on May 7, 2013, while at her home in Banning surrounded by her family. She was born July 6, 1947 in Manila, Philippines. Evelyn retired from Palm Springs Unified School District after serving as a registar for Cathedral City for 14 years. She danced with Polynesia Halau OTiana and blessed many with her gracefulness and love of hula. Originally posted here: News Obituaries … Continue reading

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Researchers receive career awards

Posted: Published on June 11th, 2013

Five up-and-coming University of Otago scholars, described as ''shining examples'' of academic talent, have been recognised through Early Career Awards for Distinction in Research. Recipients of the university's latest annual early career awards are Dr Karen Brouneus, National Centre for Peace and Conflict Studies; Dr Lyndie Foster Page, dentistry; Dr Carla Meledandri, chemistry; Dr Virginia Toy, geology; and Dr Suetonia Palmer, of the Christchurch campus. Their research spans the psychological aspects of peace-building, improving young people's oral health, developing nanoscale materials for nanomedicine, as well as structural geology and seismic processes, and improving kidney disease treatment. Announcing the awards, the deputy vice-chancellor, research and enterprise, Prof Richard Blaikie said the five scholars were ''shining examples'' of the depth and breadth of talent among the university's up-and-coming researchers. Their work was already creating ''new knowledge that underpins improvements in health, technology, social wellbeing and our understanding of environmental processes'' . The five academics were well-placed to be among Otago's future research leaders, Prof Blaikie said. Each award winner receives a $5000 grant to use for research and scholarly development, and becomes a member of the university's O-Zone group of early-to-mid career researchers. Dr Brouneus is a recipient of Otago's New Supervisor … Continue reading

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Seattle Genetics Announces Initiation of Phase 1/2 Trial of ADCETRIS® (Brentuximab Vedotin) in Combination with …

Posted: Published on June 10th, 2013

BOTHELL, Wash.--(BUSINESS WIRE)-- Seattle Genetics, Inc. (SGEN) today announced the initiation of a phase 1/2 clinical trial evaluating ADCETRIS (brentuximab vedotin) in combination with bendamustine for patients with Hodgkin lymphoma (HL) after first relapse. The multi-phase study is divided into two cohorts to determine the recommended dosing level and tolerability of combination use and to assess the complete remission rate associated with ADCETRIS in combination with bendamustine. Seattle Genetics is the leader in the field of antibody-drug conjugates (ADCs) and ADCETRIS is an ADC directed to CD30, a defining marker of classical HL. ADCETRIS is not approved for salvage HL patients who are deemed eligible for autologous stem cell transplant (ASCT). One of the key goals of our broad ADCETRIS clinical development program is to evaluate its use in earlier lines of HL therapy. This trial will assess the ability of ADCETRIS in combination with bendamustine to induce durable complete remissions in second-line treatment of HL patients prior to transplant, said Clay B. Siegall, Ph.D., President and Chief Executive Officer at Seattle Genetics. In this treatment setting, single-agent bendamustine has been shown to induce a high rate of remissions with limited durability. Data from an investigator-sponsored trial with single-agent ADCETRIS … Continue reading

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Stemline Therapeutics' SL-401 Receives Orphan Drug Designation for the Treatment of Blastic Plasmacytoid Dendritic …

Posted: Published on June 10th, 2013

NEW YORK, June 10, 2013 (GLOBE NEWSWIRE) -- Stemline Therapeutics, Inc. (STML) today announced that SL-401 has received Orphan Drug designation from the U.S. Food and Drug Administration (FDA) for the treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare and aggressive hematologic malignancy for which there is no effective treatment. SL-401 also has Orphan Drug status for the treatment of acute myeloid leukemia (AML). SL-401 is a novel targeted therapy directed to the interleukin-3 receptor (IL-3R) present on tumor bulk and cancer stem cells (CSCs) of multiple hematologic cancer indications. SL-401 has demonstrated single agent clinical activity in patients with advanced hematologic cancers, including BPDCN, AML, and myelodysplastic syndrome (MDS). "We are focused on the rapid development of SL-401 due to its potential for the treatment of IL-3R-expressing hematologic malignancies," commented Eric K. Rowinsky, M.D., Chief Medical Officer and Head of Research and Development at Stemline. "SL-401 is demonstrating robust clinical activity in heavily-pretreated patients with BPDCN who are refractory to available therapies, including high-dose chemotherapy and allogeneic stem cell transplantation. This Orphan Drug designation provides us with a number of benefits that further strengthen our SL-401 program. Stemline will progress SL-401 into pivotal trials in BPDCN and … Continue reading

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StemCells, Inc. Strengthens Product Development Team and Appoints Executive to Focus on Scientific and Strategic …

Posted: Published on June 10th, 2013

NEWARK, Calif., June 10, 2013 (GLOBE NEWSWIRE) -- StemCells, Inc. (STEM) today announced key hires to strengthen its product development capabilities and announced the creation of a new corporate function responsible for establishing scientific and strategic alliances and for building on the Company's existing stem cell technology platform. Eliseo Salinas, M.D., has joined the Company as Executive Vice President and Head of Research and Development, and will be responsible for the Company's research, product development and clinical translation activities. Dr. Salinas will report to Martin McGlynn, President and CEO of the Company. Ann Tsukamoto, Ph.D., who has most recently served as the Company's Executive Vice President of Research and Development, will assume the new role of Executive Vice President, Scientific and Strategic Alliances, responsible for developing the Company's alliances with research institutions, corporations, government agencies and disease foundations. Dr. Tsukamoto will continue to report to Mr. McGlynn. The Company also announced that Nicki Vasquez, Ph.D., has joined the Company as Vice President of Program and Portfolio Management, and Allyson Gage, Ph.D., has joined as Senior Director of Clinical Development. "The Company's clinical trials have so far been single-arm open-label studies, involving a small number of patients and conducted at one … Continue reading

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Newly discovered cell shows promise for liver regeneration

Posted: Published on June 10th, 2013

Washington, June 10 (ANI): Liver transplantation is the mainstay of treatment for patients with end-stage liver disease, but a new research from the Icahn School of Medicine at Mount Sinai has suggested that it may one day become possible to regenerate a liver using cell therapy in patients with liver disease. Investigators discovered that a human embryonic stem cell can be differentiated into a previously unknown liver progenitor cell, an early offspring of a stem cell, and produce mature and functional liver cells. "The discovery of the novel progenitor represents a fundamental advance in this field and potentially to the liver regeneration field using cell therapy," said the study's senior author, Valerie Gouon-Evans, PharmD, PhD, Assistant Professor, in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, at the Icahn School of Medicine at Mount Sinai. "Until now, liver transplantation has been the most successful treatment for people with liver failure, but we have a drastic shortage of organs. This discovery may help circumvent that problem," In conjunction with the laboratory of Matthew J. Evans, PhD, from the Department of Microbiology at Icahn School of Medicine at Mount Sinai, investigators demonstrated the functionality of the liver cells … Continue reading

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BrainStorm Treats 8th Patient in Phase IIa Trial; Completes Enrollment of Final 4 Patients

Posted: Published on June 10th, 2013

NEW YORK, NY and PETACH TIKVAH, ISRAEL--(Marketwired - Jun 10, 2013) - BrainStorm Cell Therapeutics (OTCQB: BCLI), a leading developer of adult stem cell technologies for neurodegenerative diseases, today announced that it has successfully treated the eighth patient in its ongoing Phase IIa ALS clinical trial at the Hadassah Medical Center in Jerusalem, Israel, thus completing treatment of the second of three cohorts. Enrollment of the final group of four patients has also been completed, and the company expects to conclude treatment of these patients by the end of the third quarter of this year. In this Phase IIa dose-escalating trial, currently underway at Hadassah under the direction of Principal Investigator Professor Dimitrios Karussis, 12 ALS patients are receiving combined intramuscular (IM) and intrathecal (IT) administration of NurOwn cells, in three cohorts, with increasing doses. The study participants will be monitored for six months following transplantation. About BrainStorm Cell Therapeutics, Inc. BrainStorm Cell Therapeutics Inc. is a biotechnology company engaged in the development of first-of-its-kind adult stem cell therapies derived from autologous bone marrow cells for the treatment of neurodegenerative diseases. The Company holds the rights to develop and commercialize its NurOwn technology through an exclusive, worldwide licensing agreement with … Continue reading

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The Sentinel commented Staffordshire cancer sufferer undergoes revolutionary treatment

Posted: Published on June 10th, 2013

CANCER sufferer Kate Blackhurst is recovering at home after undergoing a revolutionary stem cell transplant to try to beat the disease. The 20-year-old, picturedright, was offered the treatment on the NHS after being struck down with cancer twice in three years. The latest treatment saw some of Kate's healthy stem cells frozen by experts at The Queen Elizabeth Hospital, in Birmingham. She then received chemotherapy five times more powerful than a normal dose to try to kill the cancerous cells as the frozen stem cells were put back in her body during almost four weeks of treatment last month. BlueSky CVs Print voucher BlueSky CVs consultants can help you with some simple techniques that will help you feel confident and comfortable in your next interview - helping the real you to shine through Terms: 50% up front payment and 50% on completion Contact: 01538 710408 Valid until: Wednesday, June 12 2013 See the article here: The Sentinel commented Staffordshire cancer sufferer undergoes revolutionary treatment … Continue reading

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10 Days on Testosterone – Video

Posted: Published on June 10th, 2013

10 Days on Testosterone By: Brandon Randall … Continue reading

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