Public release date: 24-May-2013 [ | E-mail | Share ] Contact: Mount Sinai Press Office newsmedia@mssm.edu 212-241-9200 The Mount Sinai Hospital / Mount Sinai School of Medicine Two mutations central to the development of infantile myofibromatosis (IM)a disorder characterized by multiple tumors involving the skin, bone, and soft tissuemay provide new therapeutic targets, according to researchers from the Icahn School of Medicine at Mount Sinai. The findings, published in the American Journal of Human Genetics, may lead to new treatment options for this debilitating disease, for which the only current treatment option is repeated surgical removal of the tumors. IM is an inheritied disorder that develops in infancy or even in utero and tumors continue to present throughout life. The tumors do not metastasize, but can grow large enough to invade the tissue surrounding them causing physical limitations, disfiguration, bone destruction, intestitinal obstruction, and even death. Currently, the standard of care is to excise the tumors when possible, which can be invasive, painful, and disfiguring, and most patients require multiple surgeries throughout their lives. Led by John Martignetti, MD, PhD, Associate Professor of Genetics and Genomic Sciences, Oncological Sciences, and Pediatrics and other researchers at the Icahn School of Medicine … Continue reading →

May 23, 2013 Ethnic background plays a surprisingly large role in how diabetes develops on a cellular level, according to two new studies led by researchers at the Stanford University School of Medicine. The researchers reanalyzed disease data to demonstrate that the physiological pathways to diabetes vary between Africa and East Asia and that those differences are reflected in part by genetic differences. The studies published online simultaneously May 23 in the journals PLoS Genetics and Diabetes Care. "We have new insights into the differences in diabetes across the world, just by this new perspective applied to older studies," said Atul Butte, MD, PhD, senior author of the studies and chief of the Division of Systems Medicine and associate professor of pediatrics and of genetics. "There's more still to learn about diabetes than we knew." The early stages of type-2 diabetes, or adult-onset diabetes, can develop when the pancreas has problems creating sufficient insulin, a hormone critical for regulating blood sugar, or when the body's cells have trouble responding to insulin, a condition called "insulin resistance." Both problems will lead to the same result: too much sugar in a person's blood stream, which is the main criterion for diagnosing diabetes. … Continue reading →

Stem Cell Training Video Testimonials Stem Cell Training Video Testimonials. By: Regenestem Pembroke … Continue reading →

Medical Files By Rafael Castillo Philippine Daily Inquirer I have received a couple of queries regarding capsules or drink solutions which are supposed to boost the number of stem cells in the body and these could assist in cellular renewal or rejuvenation. I understand these are being marketed locally by direct sellers who are part of multilevel networking companies. These stem-cell-enhancing preparations come from blue-green algae sources, which as far back as I can remember, have been promoted to be a panacea for all sorts of illnesses. Apparently the claim that it can boost stem cell production or its release from the bone marrow puts a scientific basis to it, which is attuned with the times since stem cell treatment is now the exciting buzz word. I last reviewed the scientific literature on stem cell treatment earlier this year when I was requested to give a lecture partly discussing the effects of adult stem cells on the cardiovascular system. I remember coming across some articles on the potential role of blue-green algae in enhancing stem cell production but most of these studies were done either on mice and other experimental animals or in tissue cultures in the laboratory. Theres still … Continue reading →