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Human Cloning Produces Embryonic Stem Cells

Posted: Published on May 16th, 2013

Editor's Choice Academic Journal Main Category: Stem Cell Research Article Date: 16 May 2013 - 0:00 PDT Current ratings for: Human Cloning Produces Embryonic Stem Cells Stem cells derived by somatic cell nuclear transfer (SCNT) have the potential to transform into any cell type, such as bone or brain tissue cells. They can be used to treat and help understand a wide range of conditions and health problems. Stem cells come from two main sources: Experts are describing this latest achievement as one of the biggest breakthroughs in stem cell research since last year when Isreali scientistssuccessfully created the first human embryonic stem cell (hESC) lines that are free of animal contamination and whose production complies with Good Manufacturing Practices (GMP). Lead author, Shoukhrat Mitalipov, PhD, of Oregon Health & Science University in Portland, Ore., said: SCNT involves removing the nucleus of a donor cell and transferring it to an egg cell that has had its nucleus removed. SCNT creates embryos which are nearly identical to those of the donor. In the past, creating identical cells in this manner has been a major challenge. Normally a female germ cell begins to divide when it has about 150 cells - at … Continue reading

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Research and Markets: The Market for Primary Cells & Stem Cell-Derived Cells: Current and Future Opportunities

Posted: Published on May 16th, 2013

DUBLIN--(BUSINESS WIRE)-- Research and Markets (http://www.researchandmarkets.com/research/k4d3lg/the_market_for) has announced the addition of the "The Market for Primary Cells & Stem Cell-Derived Cells: Current and Future Opportunities" report to their offering. This study of the academic and pharma/biotech sectors in North America and Europe provides an analysis of the market for primary cells and an assessment of the brand equity for the leading companies who serve this market. This report also describes the emerging market for stem cell-derived differentiated cells, a potential threat -or opportunity- for this market. This study explores the following market analytics: - The number of researchers who currently or plan to use primary cells in their research - Proportion of researchers/labs who purchase primary cells - Annual lab budget associated with primary cell purchase - Market size, in terms of revenue, based on 2012 - Supplier share in terms of revenue - Market growth in terms of revenue in the next 12 months (through 2013) Go here to read the rest: Research and Markets: The Market for Primary Cells & Stem Cell-Derived Cells: Current and Future Opportunities … Continue reading

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Embryonic stem cells made from skin

Posted: Published on May 16th, 2013

US researchers have reported a breakthrough in stem cell research, describing how they have turned human skin cells into embyronic stem cells for the first time. The method described by Oregon State University scientists on Wednesday in the journal Cell, would not likely be able to create human clones, said Shoukhrat Mitalipov, senior scientist at the Oregon National Primate Research Centre. But it is an important step in research because it does not require the use of embryos in creating the type of stem cell capable of transforming into any other type of cell in the body. The technique involves transplanting an individual's DNA into an egg cell that has been stripped of genetic material, a variation of a method called somatic cell nuclear transfer. 'A thorough examination of the stem cells derived through this technique demonstrated their ability to convert just like normal embryonic stem cells, into several different cell types, including nerve cells, liver cells and heart cells,' said Mitalipov. He added that since the reprogrammed cells use genetic material from the patient, there is no concern about transplant rejection. 'While there is much work to be done in developing safe and effective stem cell treatments, we believe … Continue reading

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Scientists for the first time create human stem cells through cloning

Posted: Published on May 16th, 2013

A breakthrough in stem cell research could pave the way for new medical treatments A team of scientists have successfully cloned human embryos that can produce stem cells, a major breakthrough that could lead to new medical treatments and, potentially, human cloning. Scientists from Oregon Health and Science University, reporting their finding Wednesday in the journal Cell, said they had taken a baby's skin cells and combined them with human eggs. The result? Human embryos genetically identical to the original baby that, crucially, were able to produce fresh stem cells. SEE MORE: The eurozone's longest recession ever: By the numbers The process, known as a somatic-cell nuclear transfer (SCNT), involves taking the nucleus of one cell and implanting it into an unfertilized egg that has had its nucleus removed. "The egg 'reprograms' the DNA in the donor cell to an embryonic state and divides until it has reached the early, blastocyst stage," explains Nature's David Cyranoski. "The cells are then harvested and cultured to create a stable cell line that is genetically matched to the donor and that can become almost any cell type in the human body." SEE MORE: Anthony Weiner is still maybe running for mayor of New … Continue reading

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Researchers make embryonic stem cells from skin

Posted: Published on May 16th, 2013

US researchers have reported a breakthrough in stem cell research, describing how they have turned human skin cells into embyronic stem cells for the first time. The method described Wednesday by Oregon State University scientists in the journal Cell, would not likely be able to create human clones, said Shoukhrat Mitalipov, senior scientist at the Oregon National Primate Research Center. But it is an important step in research because it does not require the use of embryos in creating the type of stem cell capable of transforming into any other type of cell in the body. The technique involves transplanting an individual's DNA into an egg cell that has been stripped of genetic material, a variation of a method called somatic cell nuclear transfer. "A thorough examination of the stem cells derived through this technique demonstrated their ability to convert just like normal embryonic stem cells, into several different cell types, including nerve cells, liver cells and heart cells," said Mitalipov. He added that since the reprogrammed cells use genetic material from the patient, there is no concern about transplant rejection. "While there is much work to be done in developing safe and effective stem cell treatments, we believe this … Continue reading

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US researchers make embryonic stem cells from skin

Posted: Published on May 16th, 2013

US researchers have reported a breakthrough in stem cell research, describing how they have turned human skin cells into embyronic stem cells for the first time. The method described Wednesday by Oregon State University scientists in the journal Cell, would not likely be able to create human clones, said Shoukhrat Mitalipov, senior scientist at the Oregon National Primate Research Center. But it is an important step in research because it does not require the use of embryos in creating the type of stem cell capable of transforming into any other type of cell in the body. The technique involves transplanting an individual's DNA into an egg cell that has been stripped of genetic material, a variation of a method called somatic cell nuclear transfer. "A thorough examination of the stem cells derived through this technique demonstrated their ability to convert just like normal embryonic stem cells, into several different cell types, including nerve cells, liver cells and heart cells," said Mitalipov. He added that since the reprogrammed cells use genetic material from the patient, there is no concern about transplant rejection. "While there is much work to be done in developing safe and effective stem cell treatments, we believe this … Continue reading

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Angelina Jolie's double mastectomy puts genetic key to breast cancer in the spotlight

Posted: Published on May 16th, 2013

Even celebrities are mortal. They share our genes and, like us, cannot escape their inheritance. Angelina Jolies graceful and dignified account of her encounter with her own mortality in The New York Times will inspire millions. It will also shine a light on the developing science of genetic diagnosis and DNA profiling which is increasingly allowing patients at high risk of inherited diseases to be identified so that they can take preventive action. The BRCA1 and BRCA2 genes were the first to be identified in breast and ovarian cancer more than 20 years ago. The presence of faulty versions of the genes increases the risk of the diseases by at least 50 per cent, the exact proportion depending on other factors. Just as the risk varies from woman to woman, so does the response. In Ms Jolies case it was radical surgery to remove her breasts. About 3,000 women in the UK have done likewise. But for other women the decisions required may be less radical and distressing, involving modifying lifestyle, having regular mammograms or MRI scans or starting a course of preventive drugs. Only last January, the UKs National Institute for Clinical Excellence recommended for the first time in … Continue reading

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DNA sequencing set to become routine medicine

Posted: Published on May 16th, 2013

A Queensland researcher says actress Angelina Jolie is a great example of the potential benefits of genetic testing. The Hollywood star revealed this week that she has undergone a preventative double mastectomy after discovering a genetic variation dramatically increased her risk of breast cancer. Professor Matthew Brown from the University of Queensland has been awarded a Premier's Science Fellowship to research genetic testing for rheumatoid arthritis and tuberculosis. He says DNA sequencing will be a routine part of medical care within four to five years. "When you go to a GP or a specialist they will use that genetic information to say, 'well you've got this risk of getting the disease and these symptoms and I think it's likely that you've got a very early case of this'," he said. "When it's early on we can often treat those diseases much more effectively than once they're established." Court challenge Meanwhile, a legal challenge is continuing in Brisbane over patents on genetic material associated with an increased risk of breast and ovarian cancer. The BRCA1 and BRCA2 cancer genes are subject to commercial patent. A Federal Court judge extended the patent in a landmark ruling in February, but lawyer Rebecca Gilsenan … Continue reading

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Genetic Testing Market Outlook to 2017

Posted: Published on May 16th, 2013

NEW YORK, May 15, 2013 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue: Genetic Testing Market Outlook to 2017 http://www.reportlinker.com/p01182998/Genetic-Testing-Market-Outlook-to-2017.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Genomics A recent report, "Genetic Testing Market Outlook to 2017", provides an in-depth analysis of the current and future genetic testing market. A comprehensive introduction of gene-based tests, their working principles and types are covered in around a 140-page report. On account of our analysis of the past and present market trends; drivers; and existing strengths and challenges; forecast for genetic testing has been drawn, according to which, the market is likely to grow at a CAGR of around 9% during 2012-2017. Our report is an outcome of extensive interaction with industry experts which has led us to portray the updated status of genetic testing in various therapeutic areas, major geographies and significant industry applications. The genetic testing industry has seen several new product launches, active research innovations, strategic activities, launch of new DTC tests, and wider therapeutic applications. The report effectively illustrates the role of genetic testing in diseases such as Cancer, Cystic Fibrosis, and Alzheimer. It also incorporates the information on disease prevalence, available tests, and genes that cause a particular disease. … Continue reading

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Genetic medicine unit now seeing 800 new cases a year in bid to prevent inherited cancers

Posted: Published on May 16th, 2013

Genetic medicine unit now seeing 800 new cases a year in bid to prevent inherited cancers 6:00am Thursday 16th May 2013 in News By Barry Nelson, Health Editor A GENETIC medicine expert has revealed that a regional breast and ovarian cancer prevention unit set up nearly a decade ago is now seeing 800 new referrals a year. Dr Paul Brennan, director of the Northern Genetic Service, said referrals of women who have an increased risk of inherited breast or ovarian cancer had steadily increased since the service was established at James Cook University Hospital in Middlesbrough in 2004. "It was a trickle at first but we are now getting 800 new referrals a year of women with a family history of mainly breast, ovarian and colon cancer," said Dr Brennan, who also works at the International Centre for Life in Newcastle. Following the admission by actress Angelina Jolie that she has had a double mastectomy to reduce her chances of breast cancer, Dr Brennan said he now expected an increase in the number of North-East women with a family history of breast and ovarian cancer being referred to the Northern Genetic Service. "When we started the cancer family history service … Continue reading

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