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Will the Supreme Court end human gene patents after three decades?

Posted: Published on April 14th, 2013

Since the 1980s, patent lawyers have been claiming pieces of humanity's genetic code. The United States Patent and Trademark Office has granted thousands of gene patents. The Federal Circuit, the court that hears all patent appeals, has consistently ruled such patents are legal. But the judicial winds have been shifting. The Supreme Court has never ruled on the legality of gene patents. And recently, the Supreme Court has grown increasingly skeptical of the Federal Circuit's patent-friendly jurisprudence. Meanwhile, a growing number of researchers, health care providers, and public interest groups have raised concerns about the harms of gene patents. The American Civil Liberties Union estimates that more than 40 percent of genes are now patented. Those patents have created "patent thickets" that make it difficult for scientists to do genetic research and commercialize their results. Monopolies on genetic testing have raised prices and reduced patient options. On Monday, the high court will hear arguments about whether to invalidate a Utah company's patents on two genes associated with breast cancer. But the legal challenge, spearheaded by the American Civil Liberties Union and the Public Patent Foundation, could have much broader implications. A decision could invalidate thousands of patents and free medical … Continue reading

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New gene variations associated with heart rate identified

Posted: Published on April 14th, 2013

Apr. 14, 2013 Through a collaborative genome-wide study on individuals, researchers have discovered 14 new genetic variations that are associated with heart rate. Since heart rate is a marker of cardiovascular health, these findings could provide a better understanding of genetic regulation of heart beat and is a first step towards identifying targets for new drugs to treat cardiovascular disease. The study, titled, "Identification of Heart Rate-Associated Loci and Their Effects on Cardiac Conduction and Rhythm Disorders," was published online this week in the April issue of Nature Genetics. Led by researchers at the Icahn School of Medicine at Mount Sinai and the Medical Research Council Epidemiology Unit in Cambridge, UK, the collaboration involved 268 researchers from 211 institutions, as well as six large research consortia joined forces. In order to gain new insights into the genetic regulation of heart rate, Dr. Ruth Loos, Director of the Genetics of Obesity and Related Metabolic Traits Program at the Charles Bronfman Institute for Personalized Medicine at Mount Sinai and honorary investigator at the Medical Research Council Epidemiology Unit and her team, spent three years working on a genome-wide association study using data from 181,171 participants from 65 studies during 2009-2012. "Without any … Continue reading

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Study Identifies New Gene Variations Associated With Heart Rate

Posted: Published on April 14th, 2013

Findings pinpoint 14 genetic targets in humans that may provide insight for the treatment of cardiovascular disease Newswise (New York, NY April 14, 2013) Through a collaborative genome-wide study on individuals, researchers have discovered 14 new genetic variations that are associated with heart rate. Since heart rate is a marker of cardiovascular health, these findings could provide a better understanding of genetic regulation of heart beat and is a first step towards identifying targets for new drugs to treat cardiovascular disease. The study, titled, Identification of Heart Rate-Associated Loci and Their Effects on Cardiac Conduction and Rhythm Disorders, was published online this week in the April issue of Nature Genetics. Led by researchers at the Icahn School of Medicine at Mount Sinai and the Medical Research Council Epidemiology Unit in Cambridge, UK, the collaboration involved 268 researchers from 211 institutions, as well as six large research consortia joined forces. In order to gain new insights into the genetic regulation of heart rate, Dr. Ruth Loos, Director of the Genetics of Obesity and Related Metabolic Traits Program at the Charles Bronfman Institute for Personalized Medicine at Mount Sinai and honorary investigator at the Medical Research Council Epidemiology Unit and her team, … Continue reading

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Mount Sinai study identifies new gene variations associated with heart rate

Posted: Published on April 14th, 2013

Public release date: 14-Apr-2013 [ | E-mail | Share ] Contact: Renatt Brodsky Renatt.Brodsky@mountsinai.org 212-241-9200 The Mount Sinai Hospital / Mount Sinai School of Medicine (New York, NY April 14, 2013) Through a collaborative genome-wide study on individuals, researchers have discovered 14 new genetic variations that are associated with heart rate. Since heart rate is a marker of cardiovascular health, these findings could provide a better understanding of genetic regulation of heart beat and is a first step towards identifying targets for new drugs to treat cardiovascular disease. The study, titled, "Identification of Heart Rate-Associated Loci and Their Effects on Cardiac Conduction and Rhythm Disorders," was published online this week in the April issue of Nature Genetics. Led by researchers at the Icahn School of Medicine at Mount Sinai and the Medical Research Council Epidemiology Unit in Cambridge, UK, the collaboration involved 268 researchers from 211 institutions, as well as six large research consortia joined forces. In order to gain new insights into the genetic regulation of heart rate, Dr. Ruth Loos, Director of the Genetics of Obesity and Related Metabolic Traits Program at the Charles Bronfman Institute for Personalized Medicine at Mount Sinai and honorary investigator at the Medical … Continue reading

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"IPR in Biotechnology: A Live Session With Biological Researchers" at IIT Bombay – Video

Posted: Published on April 14th, 2013

"IPR in Biotechnology: A Live Session With Biological Researchers" at IIT Bombay IPR Aware World: A Social Campaign (Non-Profit Programme) Talks of following students: Gulshan Mehra Molecular Virology Lab, Hemendra Pal Singh Dhaked Molecu... By: Sandeep Kumar Khichar … Continue reading

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Janssen's experimental drug targeting 3 types of cancers gets FDA boost

Posted: Published on April 14th, 2013

Less than a year after the Food and Drug Administration began accepting applications for breakthrough therapy designations to fast-track promising new drugs, regulators have approved just 11 of 35 requests from pharmaceutical companies. Three of those approvals, however, have gone to one niche market cancer drug that Raritan-based Janssen Pharmaceuticals is developing with Pharmacyclics Inc. of Sunnyvale, Calif. The drug, called Ibrutinib, has so far proved effective at blocking three different types of blood cancers in patients who had relapsed several times after taking existing therapies. The FDA designations are for chronic lymphocytic leukemia, mantle cell lymphoma and Waldenstroms macroglobulinemia. Industry analysts say Ibrutinib has mostly flown under the radar because of its small market, but still believe it holds significant potential for its unique technology and relatively mild side effects. Last week, the FDA granted Ibrutinib its latest breakthrough designation to treat CLL, one of the most common forms of adult leukemia that affects about 16,000 Americans a year. The disease, a slow-growing cancer that starts in the white blood cells, targets the elderly, with an average survival of about five years. Clinical trials have shown Ibrutinib is effective for all CLL patients but works particularly well in those … Continue reading

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Hannity Blows Up At Austan Goolsbee Over White House Party: 'You're On Drugs! Can't Be Serious!' – Video

Posted: Published on April 14th, 2013

Hannity Blows Up At Austan Goolsbee Over White House Party:'You're On Drugs! Can't Be Serious!' 4/9/13 - Sean Hannity opened his show mocking President Obama's "Memphis Soul" White House party tonight as a "sequestration celebration." He reminded viewer... By: MichaelSavage4Prez … Continue reading

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Doing Drugs In Public Prank FAILS + EXTRAS – Video

Posted: Published on April 14th, 2013

Doing Drugs In Public Prank FAILS + EXTRAS MAIN VIDEO: http://youtu.be/6wlnHppSZaI MAIN CHANNEL: http://youtube.com/whatever FACEBOOK: http://facebook.com/whateverYT TWITTER: http://twitter.com/whatev... By: whatever2ND … Continue reading

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Addictions: sex, drugs, alcohol – Video

Posted: Published on April 14th, 2013

Addictions: sex, drugs, alcohol Video uploaded from my mobile phone. Sorry guys I new to this, once I get a newer phone or a video camera, I will start post more professional clips and inse... By: Renata Y … Continue reading

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ALZHEIMER'S DRUGS APPROVED BY THE FDA – Video

Posted: Published on April 14th, 2013

ALZHEIMER'S DRUGS APPROVED BY THE FDA http://www.alzheimer-herbs.com ALZHEIMER'S ALTERNATIVE TREATMENT AND PREVENTION http://www.alzheimer-herbs.com Although current medications cannot cure Alzhe... By: Anand Krish … Continue reading

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