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Testing for BRAF Genetic Mutation Beneficial Only in Aggressive Thyroid Cancers

Posted: Published on April 11th, 2013

Newswise PHILADELPHIA - Late stage thyroid cancer patients with aggressive disease may benefit from a genetic test, but experts caution that use of this test in early stage patients is inappropriate because it is unlikely to lead to better outcomes. Testing for BRAF V600E-positive tumors should be reserved for patients older than 45 who have more advanced disease, according to an accompanying editorial in JAMA co-authored by two Perelman School of Medicine researchers at the University of Pennsylvania. The most common form of thyroid cancer, papillary thyroid cancer (PTC), has an excellent prognosis when caught early, with five year survival rates of 98 percent. But 7 percent of people have an aggressive form of PTC that is more difficult to treat. A JAMA study looking at a test for a mutation in the BRAF gene (V600E) suggests that this gene mutation may be part of what makes the tumor so aggressive, suggesting that targeted treatments may be effective at inhibiting the BRAF function in PTC patients with advanced disease. "While thyroid cancer is treatable and has a good prognosis in most cases, the aggressive cases of PTC can be unpredictable" said editorial co-author Anne Cappola, MD, ScM, associate professor of … Continue reading

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PURTIER – Malaysia – Bkt Mertajam – NSY – Cancer – Video

Posted: Published on April 11th, 2013

PURTIER - Malaysia - Bkt Mertajam - NSY - Cancer By: Christin Lee … Continue reading

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Ed Park explains aging – iHealthTube1 – Video

Posted: Published on April 11th, 2013

Ed Park explains aging - iHealthTube1 Dr. Park was Interviewed by iHealthTube's Scott Peters at the 2012 A4M (American Academy of Anti-aging Medicine) Conference in Las Vegas. This is #1 of 10 se... By: Ed Park … Continue reading

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Stem Cell Therapy Treatment for Limb Girdle Muscular Dystrophy by Dr Alok Sharma, Mumbai, India. – Video

Posted: Published on April 11th, 2013

Stem Cell Therapy Treatment for Limb Girdle Muscular Dystrophy by Dr Alok Sharma, Mumbai, India. Stem Cell Therapy Treatment for Limb Girdle Muscular Dystrophy by Dr Alok Sharma, Mumbai, India. After Stem Cell Therapy 1. Power and movements in the finger... By: neurogenbsi … Continue reading

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Alzheimers Treatment – How To Heal It Completely – Video

Posted: Published on April 11th, 2013

Alzheimers Treatment - How To Heal It Completely http://www.tylertolman.com | alzheimers treatment: A lot of people ask me if there is an alzheimer's treatment to possibly reverse it.. Absolutely! Alzheimer... By: Tyler Tolman … Continue reading

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Kansas stem cell research bill: Meddling or progressive?

Posted: Published on April 11th, 2013

KANSAS CITY, Mo. A new bill under debate in the Kansas legislature requires KU Medical Center to create a new adult stem cell research facility, but many have concerns about how to pay for it. Pro-life lawmakers who pushed for the bill say it will help unleash stem cells life-saving potential. But critics say KU Med Center didnt even ask for this, and lawmakers arent giving them a way to pay for it. The bill has been approved in both the house and senate so it only awaits Governor Brownbacks signature, and he has indicated he supports it. The bill creates the Midwest Stem Cell Therapy Center focusing on adult stem cell research. KU Med Center didnt want to comment for this story, but in the past, it has expressed concerns about establishing this new center, because the startup costs alone are more than a million dollars, and KU says it doesnt have that money. KU Med Center says its researchers are already studying adult stem cells and they agree it is important work. But State Sen. Mary Pilcher-Cook, (R-Shawnee) says KU was doing the research on a very limited level. She wants to expand it because shes excited about … Continue reading

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Stephen Hawking visits LA stem cell lab where his disease is studied

Posted: Published on April 11th, 2013

Eric Reed / AP In this photo provided by Cedars-Sinai, Stephen Hawking gives a talk to workers at Cedars-Sinai Medical Center in Los Angeles, on Tuesday, April 9, 2013. By Alicia Chang, The Associated Press LOS ANGELES Stephen Hawking toured a stem cell laboratory Tuesday where scientists are studying ways to slow the progression of Lou Gehrig's disease, a neurological disorder that has left the British cosmologist almost completely paralyzed. After the visit, the 71-year-old Hawking urged doctors, nurses and staff at Cedars-Sinai Medical Center to support the research. Hawking recalled how he became depressed when he was diagnosed with the disease 50 years ago and initially didn't see a point in finishing his doctorate. But his attitude changed when his condition didn't progress quickly and he was able to concentrate on his studies. "Every new day became a bonus," he told a packed room. Cedars-Sinai received nearly $18 million last year from California's taxpayer-funded stem cell institute to study the debilitating disease also known as amyotrophic lateral sclerosis. ALS attacks nerve cells in the brain and spinal cord that control the muscles. People gradually have more and more trouble breathing and moving as muscles weaken and waste away. There's … Continue reading

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Hawking visits stem cell lab

Posted: Published on April 11th, 2013

Eric Reed / AP In this photo provided by Cedars-Sinai, Stephen Hawking gives a talk to workers at Cedars-Sinai Medical Center in Los Angeles, on Tuesday, April 9, 2013. By Alicia Chang, The Associated Press LOS ANGELES Stephen Hawking toured a stem cell laboratory Tuesday where scientists are studying ways to slow the progression of Lou Gehrig's disease, a neurological disorder that has left the British cosmologist almost completely paralyzed. After the visit, the 71-year-old Hawking urged doctors, nurses and staff at Cedars-Sinai Medical Center to support the research. Hawking recalled how he became depressed when he was diagnosed with the disease 50 years ago and initially didn't see a point in finishing his doctorate. But his attitude changed when his condition didn't progress quickly and he was able to concentrate on his studies. "Every new day became a bonus," he told a packed room. Cedars-Sinai received nearly $18 million last year from California's taxpayer-funded stem cell institute to study the debilitating disease also known as amyotrophic lateral sclerosis. ALS attacks nerve cells in the brain and spinal cord that control the muscles. People gradually have more and more trouble breathing and moving as muscles weaken and waste away. There's … Continue reading

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Physicist Stephen Hawking visits LA stem cell lab

Posted: Published on April 11th, 2013

LOS ANGELES (AP) Stephen Hawking toured a stem cell laboratory Tuesday where scientists are studying ways to slow the progression of Lou Gehrig's disease, a neurological disorder that has left the British cosmologist almost completely paralyzed. After the visit, the 71-year-old Hawking urged doctors, nurses and staff at Cedars-Sinai Medical Center to support the research. Hawking recalled how he became depressed when he was diagnosed with the disease 50 years ago and initially didn't see a point in finishing his doctorate. But his attitude changed when his condition didn't progress quickly and he was able to concentrate on his studies. "Every new day became a bonus," he told a packed room. Cedars-Sinai received nearly $18 million last year from California's taxpayer-funded stem cell institute to study the debilitating disease also known as amyotrophic lateral sclerosis. ALS attacks nerve cells in the brain and spinal cord that control the muscles. People gradually have more and more trouble breathing and moving as muscles weaken and waste away. There's no cure and no way to reverse the disease's progression. Few people with ALS live longer than a decade. Diagnosed at age 21 while a student at Cambridge University, Hawking has survived longer than … Continue reading

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Cardiopoietic 'Smart' Stem Cells Show Promise in Heart Failure Patients

Posted: Published on April 11th, 2013

Released: 4/10/2013 9:55 AM EDT Source Newsroom: Mayo Clinic VIDEO ALERT: Audio and video resources are available on the Mayo Clinic News Network. First-in-humans study introduces next generation cell therapy Newswise ROCHESTER, Minn. -- Translating a Mayo Clinic stem-cell discovery, an international team has demonstrated that therapy with cardiopoietic (cardiogenically-instructed) or smart stem cells can improve heart health for people suffering from heart failure. This is the first application in patients of lineage-guided stem cells for targeted regeneration of a failing organ, paving the way to development of next generation regenerative medicine solutions. Results of the clinical trial appear online of the Journal of the American College of Cardiology. The multi-center, randomized Cardiopoietic stem cell therapy in heart failure (C-CURE) trial involved heart failure patients from Belgium, Switzerland and Serbia. Patients in the control group received standard care for heart failure in accordance with established guidelines. Patients in the cell therapy arm received, in addition to standard care, cardiopoietic stem cells -- a first-in-class biotherapeutic. In this process, bone marrow was harvested from the top of the patients hip, and isolated stem cells were treated with a protein cocktail to replicate natural cues of heart development. Derived cardiopoietic stem cells … Continue reading

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