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Biogen Idec wins FDA approval for MS pill that analysts project will become blockbuster drug

Posted: Published on March 27th, 2013

By Robert Weisman, Globe Staff Federal regulators Wednesday approved Biogen Idec Inc.s first pill to treat multiple sclerosis, a decision that cements the Weston biotechnology companys dominance in the market for MS treatments and could allow thousands of patients to stop taking drugs by needle or through intravenous infusions. The Food and Drug Administration said Biogen Idec can sell the treatment, called Tecfidera, in the United States in the form of a capsule to be taken twice a day. Analysts have projected Tecfridera could become one of the best-selling drugs of all time by the end of the decade if MS patients shift from existing therapies now on the market. The company said it expects to start making the drug available within days. MS, one of the most common causes of neurological disability in young adults, is an autoimmune disorder that affects the central nervous system of about 400,000 people in the United States and 2.5 million globally. It disrupts communication between the brain and other parts of the body. Most people experience their first MS symptoms between the age of 20 and 40. No drug provides a cure for multiple sclerosis so it is important to have a variety … Continue reading

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MS patient ‘punished’ after controversial treatment

Posted: Published on March 27th, 2013

A Dartmouth woman with multiple sclerosis claims she is being denied a check-up with a vein specialist in Nova Scotia after undergoing a controversial treatment in Europe. The health minister says it shouldn't be a problem for her to see someone, but Karen Clarke said she feels punished by the medical community. These days the 59-year-old says she has renewed energy, one of the benefits she credits of a controversial treatment for MS. The numbness is gone out of my feetI died and went to heaven. It's just fantastic, she said. In September 2011, Clarke flew to Brussels where she spent her inheritance, $15,000, on what's been dubbed "liberation therapy." Doctors made an incision near her groin, and inserted a balloon to open her jugular vein. It's an unproven and contested procedure. Clarke said she knew shed be running a risk back in Nova Scotia. I was told that when I came back I wouldnt be able to see any doctors about my procedure. If I went to a neurologist they would look at me as though I was some sort of weirdo. But almost a year and a half later Clarke asked her doctor to refer her to a … Continue reading

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Common tax questions – Video

Posted: Published on March 27th, 2013

Common tax questions FOX21 News, dedicated to providing relevant news, information and weather to Southern Colorado. Go to http://FOX21news.com for the latest. By: FOX21NewsColorado … Continue reading

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Exercise is Medicine at the University of South Florida – Video

Posted: Published on March 27th, 2013

Exercise is Medicine at the University of South Florida By: wellnessusf … Continue reading

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Functional ovarian tissue engineered in lab

Posted: Published on March 27th, 2013

Mar. 26, 2013 A proof-of-concept study suggests the possibility of engineering artificial ovaries in the lab to provide a more natural option for hormone replacement therapy for women. In Biomaterials, a team from Wake Forest Baptist Medical Center's Institute for Regenerative Medicine report that in the laboratory setting, engineered ovaries showed sustained release of the sex hormones estrogen and progesterone. Although there are medications that can compensate for the loss of female sex hormone production, the drugs are often not recommended for long-term use due to the increased risk of heart disease and breast cancer. "Our goal is to develop a tissue- or cell-based hormone therapy -- essentially an artificial ovary- to deliver sex hormones in a more natural manner than drugs," said Emmanuel C. Opara, Ph.D., professor of regenerative medicine and senior author. "A bioartificial ovary has the potential to secrete hormones in a natural way based on the body's needs, rather than the patient taking a specific dose of drugs each day." Ovaries are the female reproductive organs that produce eggs that are fertilized for pregnancy as well as secrete hormones important to bone and cardiovascular health. The loss of ovarian function can be due to surgical removal, … Continue reading

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Toward a Natural HRT

Posted: Published on March 27th, 2013

A proof-of-concept study suggests the possibility of engineering artificial ovaries in the lab to provide a more natural option for hormone replacement therapy for women. A team from Wake Forest Baptist Medical Center's Institute for Regenerative Medicine report that in the laboratory setting, engineered ovaries showed sustained release of the sex hormones estrogen and progesterone. The study was published in the journal Biomaterials. A release from the center notes that although there are medications that can compensate for the loss of female sex hormone production, the drugs are often not recommended for long-term use due to the increased risk of heart disease and breast cancer. Senior author Emmanuel C. Opara, Ph.D. is quoted as saying, "Our goal is to develop a tissue- or cell-based hormone therapy essentially an artificial ovary to deliver sex hormones in a more natural manner than drugs. A bioartificial ovary has the potential to secrete hormones in a natural way based on the body's needs, rather than the patient taking a specific dose of drugs each day." Copyright 1997 - 2013 ThirdAge Media, LLC. All rights reserved. View original post here: Toward a Natural HRT … Continue reading

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Researchers Build Functional Ovarian Tissue in Lab

Posted: Published on March 27th, 2013

Bioartificial Ovary May One Day Provide Natural Hormone Replacement Therapy Newswise WINSTON-SALEM, N.C. March 26, 2013 A proof-of-concept study suggests the possibility of engineering artificial ovaries in the lab to provide a more natural option for hormone replacement therapy for women. In Biomaterials, a team from Wake Forest Baptist Medical Centers Institute for Regenerative Medicine report that in the laboratory setting, engineered ovaries showed sustained release of the sex hormones estrogen and progesterone. Although there are medications that can compensate for the loss of female sex hormone production, the drugs are often not recommended for long-term use due to the increased risk of heart disease and breast cancer. Our goal is to develop a tissue- or cell-based hormone therapy essentially an artificial ovary to deliver sex hormones in a more natural manner than drugs, said Emmanuel C. Opara, Ph.D., professor of regenerative medicine and senior author. A bioartificial ovary has the potential to secrete hormones in a natural way based on the bodys needs, rather than the patient taking a specific dose of drugs each day. Ovaries are the female reproductive organs that produce eggs that are fertilized for pregnancy as well as secrete hormones important to bone and cardiovascular … Continue reading

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Certain breast cancers have a trait that could be attacked by new therapies

Posted: Published on March 27th, 2013

Public release date: 27-Mar-2013 [ | E-mail | Share ] Contact: Tim Wall walltj@missouri.edu 573-882-3346 University of Missouri-Columbia More than 100 women per day die from breast cancer in the United States. The odds of developing breast cancer increase for women taking hormone replacement therapy to avoid the effects of menopause. New research by University of Missouri scientist Salman Hyder may lead to treatments for breast cancers associated with taking these synthetic hormones. Hyder, along with an international team, found that hormone-therapy-related breast cancer cells have a physical feature that could be attacked by cancer therapies. "We identified a specific cell membrane protein that blocks cell death in breast cancer cells and allows these cells to grow in response to hormone replacement therapy," said Hyder. "Others have observed an over-abundance of these proteins in a population of breast cancer cells which may explain increased risk of breast cancer in women who consume hormone replacement therapy. Therapies could be developed that would block the activity of these cell membrane proteins, which would make cancer cells more likely to die. The membrane protein is known as PGRMC1." The proteins identified by Hyder and his colleagues were affected by progestin, one of the … Continue reading

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Biology Group 30 (11 AM) Stem Cell Research Project – Video

Posted: Published on March 27th, 2013

Biology Group 30 (11 AM) Stem Cell Research Project New Project 1. By: Erin Thorn … Continue reading

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GREG PHILLIPS Stem Cell Research – Video

Posted: Published on March 27th, 2013

GREG PHILLIPS Stem Cell Research Stem Cell Research. By: Michael Michaux … Continue reading

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