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House approves bill requiring KU Medical Center to establish stem cell research center

Posted: Published on March 27th, 2013

Topeka A bill supported by abortion opponents that would require the Kansas University Medical Center to start a center on adult stem cell research was approved by the House on Tuesday. State Rep. David Crum, R-Augusta, described the bill as pro-life, in that adult stem cell research has the potential to establish cures that improve the quality of life and extend life. But opponents of Senate Bill 199 said legislators shouldnt mandate KU start a center without any state funding, while many of those same legislators also voted to cut funding to the school in the state appropriations bill. And the opponents said KU did not ask for the bill and that traditionally the startup of a research and treatment center requires a lengthy planning process that brings together school leaders, researchers and the business community before approaching the Legislature. We are in uncharted territory, state Rep. Barbara Bollier, R-Mission Hills, said. Stem cell research and therapy is incredibly complex, Bollier said. The doctors and researchers who are involved know what they are doing and they dont need us to set up a specific stem cell treatment center. Bollier tried to add an amendment to the bill that she said … Continue reading

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ViaCord Releases 250th Cord Blood Stem Cell Unit

Posted: Published on March 27th, 2013

WALTHAM, Mass.--(BUSINESS WIRE)-- ViaCord, PerkinElmers family cord blood and tissue preservation business, announced today the release of its 250th umbilical cord blood stem cell unit for use in medical treatments and clinical trials. For nearly 20 years, ViaCord has released life-saving stem cells for disease therapies using a proven method of processing and cryopreserving cord blood. To date, ViaCord has released more units for use in medical treatments and clinical trialsthan any other family bank. Reaching this milestone is a testament to our dedication to improving the quality of life for families, said Morey Kraus, Chief Scientific Officer, ViaCord. The benefits of cord blood banking are constantly evolving as research, some of which ViaCord has been instrumental in supporting, continues to expand the number of diseases treated. We are excited to continue to assist families who have chosen to bank their newborns stem cells. Cord blood stem cells have been used in the treatment of nearly 80 diseases, and more than 30,000 treatments have been conducted worldwide using cord blood stem cells. ViaCord has released stem cells for the treatment of diseases ranging from acute lymphoblastic leukemia, thalassemia major and sickle cell disease. ViaCords 250th unit was used to treat … Continue reading

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Gina Lollobrigida jewels estimated at $3 million to be sold for charity

Posted: Published on March 27th, 2013

Gina Lollobrigida jewels: The Italian actress plans to sell 22 jewels in an auction to raise funds for stem cell research. Gina Lollobrigida says it's time to give back. Italian actress Gina Lollobrigida, one of the leading sex symbols of the 1950s and 1960s, is selling some of her diamond jewelry to raise money for stem cell research, saying now is the time to give back for the fortunate life she has had. Subscribe Today to the Monitor Click Here for your FREE 30 DAYS of The Christian Science Monitor Weekly Digital Edition After a humble, rural upbringing, Lollobrigida played opposite Hollywood stars such as Humphrey Bogart, Rock Hudson, Burt Lancaster, Tony Curtis and Frank Sinatra. As her career took off in France, Italy and Hollywood, Lollobrigida said she started to collect jewels from Bulgari, always buying them herself and enjoying the purchasing power of her hard work. Now 85 and having largely left acting in the 1980s for photojournalism, humanitarian work and sculpting, Lollobrigida said it was time to put the jewelry to good use. Some 22 jewels from her collection will be auctioned by Sotheby's in Geneva on May 14 after going on display in London, New York … Continue reading

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Mount Sinai Leads Global Program Using Stem Cells, Collaborates with The New York Stem Cell Foundation to Accelerate …

Posted: Published on March 27th, 2013

Newswise Sam Gandy, MD, PhD, of the Icahn School of Medicine at Mount Sinai is leading an international team of researchers working to reprogram skin cells into brain cells to gain a better understanding of Alzheimers disease (AD). As part of the Consortium, Dr. Gandy is collaborating with Scott Noggle, PhD, the NYSCF Charles Evans Senior Research Fellow for Alzheimers Disease and Director of the New York Stem Cell Foundation (NYSCF)s laboratory in Manhattan. Dr. Gandy heads the Stem Cell Research Consortium funded by the Cure Alzheimers Fund (CAF). The Consortium consists of six institutions that plan to directly investigate, for the first time, brain cells in petri dishes from individual patients who have the common form of AD. Dr. Gandy is working with Dr. Noggles team to reprogram skin cells from AD patients into brain cells using stem-cell technology. The research team will obtain and monitor adult AD brain cells, providing not only a way to study the causes of the disease but also a system for discovering potentially effective drugs. The strategy has been nicknamed the patient-specific disease in a dish and enables studies on a time scale of minutes or hours, compared with mouse model testing, which … Continue reading

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International Stem Cell Corporation to Host Conference Call Thursday, March 28 to Discuss Year End 2012 Financial …

Posted: Published on March 27th, 2013

CARLSBAD, CA--(Marketwire - Mar 26, 2013) - International Stem Cell Corporation (OTCQB: ISCO) (www.internationalstemcell.com) ("ISCO" or "the Company"), a California-based biotechnology company, today announced the management will host a conference call on Thursday, March 28, 2013 to provide a business update and discuss its financial results for the year ended December 31, 2012. Dr. Simon Craw, Executive Vice President and Ms. Linh Nguyen, Chief Financial Officer of International Stem Cell, will host the conference call. To attend the call, please use the dial in information below: Date: Thursday March 28, 2013 Time: 11:00 a.m. ET Conference Line (U.S.): 1-877-941-2068 International Dial-In: 1-480-629-9712 Conference ID: 4610666 Webcast: http://public.viavid.com/player/index.php?id=104040 Please log in at least 10 minutes before the call start time to ensure timely participation. A playback of the call will be available from 2:00 p.m. ET on March 28, 2013 to 11:59 p.m. ET on April 11, 2013. Teleconference Replay Details: US Domestic: 1-877-870-5176 International: 1-858-384-5517 Conference ID: 4610666 About International Stem Cell Corporation International Stem Cell Corporation is focused on the therapeutic applications of human parthenogenetic stem cells (hpSCs) and the development and commercialization of cell-based research and cosmetic products. ISCO's core technology, parthenogenesis, results in the creation of pluripotent … Continue reading

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Life Technologies Announces SFDA Clearance for its 3500xL Dx Genetic Analyzer in China and the Launch of 10 Assays …

Posted: Published on March 27th, 2013

SHANGHAI, March 27, 2013 /PRNewswire/ --Life Technologies Corporation (LIFE) today announced that its Applied Biosystems 3500xL Dx Genetic Analyzer has been approved by China's State Food and Drug Administration (SFDA) for clinical diagnostic use in China and the launch of 10 Assays from its joint venture with Daan Gene. The development marks a major extension of Life Technologies' capabilities to serve the clinical end market in China with Sanger-based solutions. The 3500xL Dx is an automated 24 capillary-based Sanger Sequencer designed for a wide range of sequencing applications. It delivers high quality performance, higher throughput and increased productivity for clinical laboratories around the world. Together with Life Technologies' genetic analyzer 3500 Dx that was approved by SFDA for IVD use in 2011 in China, the 3500 series genetic analyzers are intended for use in a wide range of applications in the process of clinical research, including de novo sequencing and mutational profiling as well as HLA typing. The newly expanded offering of both the 3500 Dx and the 3500xL Dx provides hospitals of all sizes the flexibility they need to meet their unique throughput demands. Based on the 3500 Dx series platform, ten assays have been developed or licensed by … Continue reading

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Childhood asthma tied to combination of genes and wheezing illness

Posted: Published on March 27th, 2013

Public release date: 27-Mar-2013 [ | E-mail | Share ] Contact: John Easton john.easton@uchospitals.edu 773-795-5225 University of Chicago Medical Center About 90 percent of children with two copies of a common genetic variation and who wheezed when they caught a cold early in life went on to develop asthma by age 6, according to a study to be published March 28 by the New England Journal of Medicine. These children, all from families with a history of asthma or allergies, were nearly four times as likely to develop the disease as those who lacked the genetic variation and did not wheeze. The effects of eachthe genetic variation and wheezing illness caused by a human rhinovirus infectionare not merely additive but also interactive, the authors say. The genetic marker studied, a variation on chromosome 17, is common. Half of the children in the study had one copy and 25 percent had two. Colds caused by human rhinoviruses also are extremely common, affecting almost all infants. But the combination of genetic risk plus the wheezing response to rhinovirus infection by children under age 3 was tightly linked to the development of asthma by age 6. "We found that the interaction between this … Continue reading

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Study finds strong genetic component to childhood obesity

Posted: Published on March 27th, 2013

Public release date: 26-Mar-2013 [ | E-mail | Share ] Contact: Rosie Waldron r.waldron@ucl.ac.uk 020-767-99041 University College London Previous research has shown that obesity runs in families, and twin studies suggest that this is largely due to genetic factors, with heritability estimates over 50%. 32 genes have been identified as risk factors for obesity but previous analyses suggest that these genes alone cannot fully explain the high level of heritability in childhood obesity, as together they explain only 2% of individual differences in childhood body weight. This has led to a problem of 'missing heritability'. In this study, researchers used a new method called Genome-wide Complex Trait Analysis (GCTA), to investigate the molecular genetic heritability of body weight in children. GCTA takes advantage of the fact that some people are more genetically similar to one another than others, by chance; and looks to see whether individuals who just happen to be more genetically similar might also be more similar in weight. Using this approach, GCTA estimates the combined effects of all known common genes across the whole genome, associated with childhood body weight. The study is based on data from a population-based cohort of 2,269 children aged between eight and … Continue reading

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Scientists ID genetic markers tied to breast, prostate, ovarian cancer; no quick payoff seen

Posted: Published on March 27th, 2013

NEW YORK, N.Y. - A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person's risk for breast, ovarian or prostate cancer, scientists reported Wednesday. It's the latest mega-collaboration to learn more about the intricate mechanisms that lead to cancer. And while the headway seems significant in many ways, the potential payoff for ordinary people is mostly this: Someday there may be genetic tests that help identify women with the most to gain from mammograms, and men who could benefit most from PSA tests and prostate biopsies. And perhaps farther in the future these genetic clues might lead to new treatments. "This adds another piece to the puzzle," said Harpal Kumar, chief executive of Cancer Research U.K., the charity which funded much of the research. One analysis suggests that among men whose family history gives them roughly a 20 per cent lifetime risk for prostate cancer, such genetic markers could identify those whose real risk is 60 per cent. The markers also could make a difference for women with BRCA gene mutations, which puts them at high risk for breast cancer. Researchers … Continue reading

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Genetic Markers For Cancer Risk Identified In Huge International Effort

Posted: Published on March 27th, 2013

NEW YORK A huge international effort involving more than 100 institutions and genetic tests on 200,000 people has uncovered dozens of signposts in DNA that can help reveal further a person's risk for breast, ovarian or prostate cancer, scientists reported Wednesday. It's the latest mega-collaboration to learn more about the intricate mechanisms that lead to cancer. And while the headway seems significant in many ways, the potential payoff for ordinary people is mostly this: Someday there may be genetic tests that help identify women with the most to gain from mammograms, and men who could benefit most from PSA tests and prostate biopsies. And perhaps farther in the future these genetic clues might lead to new treatments. "This adds another piece to the puzzle," said Harpal Kumar, chief executive of Cancer Research U.K., the charity which funded much of the research. One analysis suggests that among men whose family history gives them roughly a 20 percent lifetime risk for prostate cancer, such genetic markers could identify those whose real risk is 60 percent. The markers also could make a difference for women with BRCA gene mutations, which puts them at high risk for breast cancer. Researchers may be able to … Continue reading

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