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Pope descends Popemobile to bless disabled man before Inaugural Mass – Video

Posted: Published on March 22nd, 2013

Pope descends Popemobile to bless disabled man before Inaugural Mass http://en.romereports.com. By: romereports … Continue reading

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Spot the Signs – Audio Described – Video

Posted: Published on March 22nd, 2013

Spot the Signs - Audio Described Age-related macular degeneration (AMD) can damage your sight in just three months. If you're over 50, you're most at risk. RNIB can help you spot the signs o... By: rnibuk … Continue reading

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New method developed to expand blood stem cells for bone marrow transplant

Posted: Published on March 22nd, 2013

Public release date: 21-Mar-2013 [ | E-mail | Share ] Contact: Lauren Woods Law2014@med.cornell.edu 646-317-7401 Weill Cornell Medical College NEW YORK (March 21, 2013) -- More than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system. In the journal Blood, Weill Cornell researchers and collaborators from Memorial-Sloan Kettering Cancer Center describe how they engineered a protein to amplify adult HSCs once they were extracted from the bone marrow of a donor. The engineered protein maintains the expanded HSCs in a stem-like state -- meaning, they will not differentiate into specialized blood cell types before they are transplanted in the recipient's bone marrow. Finding a bone marrow donor match is challenging and the number of bone marrow cells from a single harvest procedure are often not sufficient for a transplant. Additional rounds of bone marrow harvest and clinical applications to mobilize blood stem cells are often required. … Continue reading

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Cellular Dynamics receives $16 million research grant

Posted: Published on March 22nd, 2013

MILWAUKEE - A Madison company said Thursday it has been awarded $16 million to manufacture stem cell lines for research. Cellular Dynamics International Inc. will receive the grant from the California Institute for Regenerative Medicine, which was established with a $3 billion fund approved by taxpayers in California to accelerate stem cell research in that state. Cellular Dynamics was awarded $16 million to create three stem cell lines -- called induced pluripotent stem cells, or iPSCs -- that can be used for research on Alzheimer's disease, autism spectrum disorders, liver diseases, cardiovascular diseases and many other ailments. According to the National Institutes of Health, iPSCs -- although needing additional research -- already are useful tools for drug development and modeling of diseases, and scientists hope to use them in transplantation medicine. The institute also awarded almost $10 million to Coriell Institute for Medical Research, of Camden, N.J., to set up and "biobank" the iPSC lines. "The California Institute for Regenerative Medicine is a world leader in funding stem cell research," Bob Palay, chairman and chief executive of Cellular Dynamics, said in a statement. "Their human iPSC banking initiative will create the world's largest human iPSC bank." Cellular Dynamics was founded … Continue reading

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Institute teaches stem cell researchers how to give elevator pitch

Posted: Published on March 22nd, 2013

SAN FRANCISCO (KGO) -- There's no doubt that the science behind stem cell research can be complex. So, now the California Institute for Regenerative Medicine is launching a unique effort to help the public better understand it, all by getting researchers to rethink the way they communicate. Bettina Steffen, M.D., works for CIRM -- the taxpayer funded institute that pays for stem cell research. What exactly does she do? She'll explain it on an elevator ride. "I fund stem cell research, finding an interesting discovery in a laboratory model, and try to help them move that to clinics so it can be studied safely in humans," she said. Directors at the institute scored the videos on brevity, clarity, and creativity. Some of the researchers were born performers, while others looked as if they'd be slightly more comfortable in front of a microscope than a camera, and there were those whose mastery of cell biology was a bit stronger than their mastery of the 30 second deadline. While all the contestants were brilliant researchers and good sports on top of it, CIRM Science Officer Kevin Whittlesey believes their future often hinges on convincing the people paying the bills. "By and large … Continue reading

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International Stem Cell Corp. to Host Conference Call on Friday, March 22 to Discuss Positive Study Data of Parkinson …

Posted: Published on March 22nd, 2013

CARLSBAD, CA--(Marketwire - Mar 21, 2013) - International Stem Cell Corporation ( OTCQB : ISCO ) (www.internationalstemcell.com) ("ISCO" or "the Company"), a California-based biotechnology company, today announced that the Company will host a conference call on Friday, March 22, 2013 to discuss results of its Parkinson's Disease studythat it presented at the American Academy of Neurology 65th Annual Meeting (AAN) on March 20, 2013. Dr. Ruslan Semechkin, Vice President of Research and Development for ISCO and Dr. Simon Craw, Executive Vice President will host the call. Date: March 22, 2013 Time: 11:00 a.m. ET Conference Line (U.S.): 1-888-846-5003 International Dial-In: 1-480-629-9856 Conference ID: 4610097 Webcast: http://public.viavid.com/index.php?id=104002 Please log in at least 10-minutes before the start time to ensure timely participation. A slide deck accompanying the presentation is available through newsroom section on the Company's website: http://www.internationalstemcell.com/Company_Presentation. A playback of the call will be available from 2:00 p.m. ET on March 22, 2013 to 11:59 p.m. ET on April 4, 2013. To listen, call 1-877-870-5176 within the United States or 1-858-384-5517 when calling internationally. Please use the replay pin number 4610097. About International Stem Cell Corporation International Stem Cell Corporation is focused on the therapeutic applications of human parthenogenetic stem cells … Continue reading

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Global Survey Underscores Importance of Patient Education and Engagement in Personalised Medicine

Posted: Published on March 22nd, 2013

DUBLIN, March 21, 2013 /PRNewswire/ -- Nearly two out of three people in four major European countries have no awareness of personalised medicine - despite the fact that this evolving discipline has vast implications for Europe's healthcare issues and Europeans' personal health. These statistics presented today at the European Alliance for Personalised Medicine (EAPM) conference taking place in Dublin, in association with the Irish EU Presidency, were part of the PACE Cancer Perception Index that studied knowledge and attitudes about cancer treatment and care, the healthcare system and patient involvement. PACE, a Lilly Oncology initiative, stands for Patient Access to Cancer care Excellence. The EAPM Conference on Innovation and Patient Access to Personalised Medicine brought together researchers, patients, healthcare professionals, payers, regulators, policymakers and industry to evaluate the potential and the development of personalised medicine in light of the European economic crisis.[i] Irish Minister of Health Dr. James Reilly stressed the potential of personalised medicine "to provide solutions that are better tailored to the individual patient than traditional 'one size fits all' medicinal products."[ii] "Personalised medicine is a promising concept," said Tonio Borg, European Union (EU) Commissioner for Health and Consumers. "As patients are divided into groups based on their … Continue reading

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Affymetrix Signs Contract With UK Biobank to Genotype 500,000 UK Individuals in the Largest Ever Study of Genetic and …

Posted: Published on March 22nd, 2013

SANTA CLARA, Calif.--(BUSINESS WIRE)-- Affymetrix, Inc. (AFFX) today announced that it has signed a contract with UK Biobank to genotype 500,000 DNA samples donated by UK residents as part of a prospective epidemiological study of complex diseases that are of great relevance to public health. Affymetrix Axiom Genotyping Solution will be used to generate billions of high-quality genotypes which will provide UK Biobank and the research community with valuable insight to genetic factors underlying human diseases for improved prevention, diagnosis, and treatment of conditions such as heart disease, cancer, and diabetes. Professor Rory Collins, UK Biobank CEO and Principal Investigator said: UK Biobank is pleased to join forces with Affymetrix for this next phase of the UK Biobank project. The two organizations will work closely together to ensure that world class data are provided quickly and securely to help scientists working on the causes of a wide range of life-threatening and disabling diseases. I urge health scientists everywhere to think carefully about how this resource could be used to help their research, and to register with UK Biobank. I am also very grateful to the half a million participants whose generosity and vision for the future has allowedthis resource to … Continue reading

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Study Finds New Genetic Test Better Predicts Mother’s Risk of Having a Child With Fragile X Syndrome

Posted: Published on March 22nd, 2013

AUSTIN, Texas, March 21, 2013 /PRNewswire/ -- Asuragen Inc., a leading molecular diagnostics company, today announced results from a study demonstrating that a new molecular test called Xpansion Interpreter can improve the determination of a woman's risk of having a child with fragile X syndrome, the most common inherited cause of intellectual disability and autism, compared to existing risk measures. The Xpansion Interpreter Test is based on a technology breakthrough that reveals both the number and position of "interrupting" DNA sequences in the fragile X gene of the mother and more accurately estimates the likelihood that her child will have fragile X syndrome. The study will be published in the April issue of the American Journal of Medical Genetics and presented today at the 2013 American College of Medical Genetics and Genomics Annual Clinical Genetics Meeting in Phoenix, AZ. To view the multimedia assets associated with this release, please click: http://www.multivu.com/mnr/60719-asuragen-xpansion-interpreter-xi-test-data-fragile-x-syndrome-autism "The increased testing of women for fragile X status has led to the identification of carriers whose risk of having a child with fragile X syndrome is unknown," said Sally Nolin, Ph.D., Director of the Fragile X Laboratory at the New York Institute for Basic Research in Developmental Disabilities … Continue reading

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For the first time, recommendations offer guidance about incidental genetic findings

Posted: Published on March 22nd, 2013

Public release date: 21-Mar-2013 [ | E-mail | Share ] Contact: Tom Langford tlangford@partners.org 617-534-1605 Brigham and Women's Hospital Boston In a highly anticipated report, landmark recommendations on the handling of incidental findings in clinical genome and exome sequencing are being issued from the American College of Medical Genetics and Genomics (ACMG). A report of the recommendations, led by Robert C. Green, MD, MPH, a medical geneticist at Brigham and Women's Hospital (BWH), outlines for the first time a minimum list of genetic conditions, genes and variants that laboratories performing clinical sequencing should seek and report to the physicians that ordered the testing -- regardless of the original reasons for which the test was ordered. "If, as expected, these recommendations are adopted by laboratories and clinicians, they will have important implications," said Green, who also co-chaired the ACMG Working Group that developed the recommendations. "As clinical sequencing becomes more widespread, laboratories are looking for guidance on how and what should be communicated to clinicians when results are analyzed. These recommendations will allow a small percentage of families to learn unexpected but potentially life-saving information about an illness they may have never suspected they were at risk for." The recommendations are … Continue reading

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