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Cytomedix to Host Fourth Quarter and Fiscal Year 2012 Financial Results Conference Call on Tuesday, March 19, 2013

Posted: Published on March 13th, 2013

GAITHERSBURG, MD--(Marketwire - Mar 12, 2013) - Cytomedix, Inc. ( OTCQX : CMXI ) (the "Company"), a regenerative therapies company commercializing and developing innovative platelet and adult stem cell technologies, announced today that the Company will release financial results for the three- and twelve-months ended December 31, 2012, after the close of the market on Monday, March 18, 2013. Martin Rosendale, Chief Executive Officer, and Andrew Maslan, Chief Financial Officer, will host a conference call beginning at 8:30am Eastern time on Tuesday, March 19, 2012 to discuss the fourth quarter and fiscal year 2012 results and to answer questions. James Hinson, MD, Chief Medical Officer, will join the call to discuss progress made on rolling out Coverage with Evidence Development for AutoloGel. Conference Call & Webcast Tuesday, March 19, 2013 @ 8:30am Eastern/5:30am Pacific Domestic dial in: 866-700-0161 International: 617-213-8832 Passcode: 42664770 Webcast: http://www.cytomedix.com Replays - Available through March 26, 2013 Domestic: 888-286-8010 International: 617-801-6888 Passcode: 23856984 About Cytomedix, Inc. Cytomedix, Inc. is an autologous regenerative therapies company commercializing innovative platelet technologies for orthopedics and wound care with a pipeline of adult stem cell therapies for tissue repair. The Company markets the AutoloGel System, a device for the production of … Continue reading

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BioTime to Present at 25th Annual ROTH Conference

Posted: Published on March 13th, 2013

ALAMEDA, Calif.--(BUSINESS WIRE)-- BioTime, Inc. (NYSE MKT: BTX), a biotechnology company that develops and markets products in the field of regenerative medicine, today announced that Dr. Michael D. West, Chief Executive Officer, will present a corporate overview of BioTime and its subsidiaries at the 25th Annual ROTH Conference. The presentation will take place on Monday, March 18, 2013 at 5:30 p.m. PDT at The Ritz-Carlton, Laguna Niguel, in Dana Point, California. The presentation will be webcast and available online at the Investors section of the website at http://www.biotimeinc.com and at http://wsw.com/webcast/roth27/btx/. About BioTime, Inc. BioTime, headquartered in Alameda, California, is a biotechnology company focused on regenerative medicine and blood plasma volume expanders. Its broad platform of stem cell technologies is enhanced through subsidiaries focused on specific fields of application. BioTime develops and markets research products in the fields of stem cells and regenerative medicine, including a wide array of proprietary PureStem cell lines, HyStem hydrogels, culture media, and differentiation kits. BioTime is developing Renevia (formerly known as HyStem-Rx), a biocompatible, implantable hyaluronan and collagen-based matrix for cell delivery in human clinical applications. BioTime's therapeutic product development strategy is pursued through subsidiaries that focus on specific organ systems and related diseases … Continue reading

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NIH Funding Puts Researchers on Path to Restoring Vision Loss From Diabetic Eye Disease

Posted: Published on March 13th, 2013

Newswise INDIANAPOLIS -- Researchers at the Eugene and Marilyn Glick Eye Institute and the Indiana Center for Vascular Biology at Indiana University School of Medicine are on the cusp of perfecting stem cell treatments that would halt and potentially reverse vision loss caused by diabetic retinopathy. Rajashekhar Gangaraju, Ph.D., assistant professor of ophthalmology and cellular and integrative physiology, Eugene and Marilyn Glick Eye Institute and the Indiana Center for Vascular Biology and Medicine, is the principal investigator in the nearly $2 million study funded by the National Eye Institute, part of the National Institutes of Health. Long interested in the causes and effects of diabetic retinopathy his father and grandfather both suffered from diabetes and resulting vision loss Dr. Gangaraju has focused his research on retinal vascular biology. His research team consists of Keith L. March, M.D., Ph.D., director, Indiana Center for Vascular Biology and Medicine and the Center for Regenerative Medicine, Maria B. Grant, M.D., currently at the University of Florida (and joining the Glick Eye Institute as senior chair in July) and others at the Glick Eye Institute and IU School of Medicine who are conducting complementary research. Dr. Gangaraju said the five years of funding puts researchers … Continue reading

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ACT’s Dr. Robert Lanza Voted Top 4 “Most Influential People on Stem Cells”

Posted: Published on March 13th, 2013

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Using fat to fight brain cancer: Stem cells from human adipose tissue used to chase migrating cancer cells

Posted: Published on March 13th, 2013

Mar. 12, 2013 In laboratory studies, Johns Hopkins researchers say they have found that stem cells from a patient's own fat may have the potential to deliver new treatments directly into the brain after the surgical removal of a glioblastoma, the most common and aggressive form of brain tumor. The investigators say so-called mesenchymal stem cells (MSCs) have an unexplained ability to seek out damaged cells, such as those involved in cancer, and may provide clinicians a new tool for accessing difficult-to-reach parts of the brain where cancer cells can hide and proliferate anew. The researchers say harvesting MSCs from fat is less invasive and less expensive than getting them from bone marrow, a more commonly studied method. Results of the Johns Hopkins proof-of-principle study are described online in the journal PLOS ONE. "The biggest challenge in brain cancer is the migration of cancer cells. Even when we remove the tumor, some of the cells have already slipped away and are causing damage somewhere else," says study leader Alfredo Quinones-Hinojosa, M.D., a professor of neurosurgery, oncology and neuroscience at the Johns Hopkins University School of Medicine. "Building off our findings, we may be able to find a way to arm … Continue reading

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VistaGen Therapeutics to Present Enhancements and Expanded Validation of LiverSafe 3D(TM) at Society of Toxicology's …

Posted: Published on March 13th, 2013

SOUTH SAN FRANCISCO, CA--(Marketwire - Mar 12, 2013) - VistaGen Therapeutics, Inc. ( OTCQB : VSTA ), a biotechnology company applying stem cell technology for drug rescue, predictive toxicology and drug metabolism assays, today announces that it will present key enhancements to LiverSafe 3D, its human liver cell-based bioassay system designed to predict liver toxicity and drug metabolism issues, in a poster presentation at the Society of Toxicology's 52nd Annual Meeting, the world's premier toxicology conference,in San Antonio, Texas, onMarch 12, 2013, at 11:00 am PDT. Dr. Kristina Bonham, Senior Scientist, Hepatocyte Biology Project Leader, will present VistaGen's poster titled "Selection of CYP3A4+hESC-derived Hepatocytes for Drug Metabolism and Toxicity Assays," which will detail the following expanded data: H. Ralph Snodgrass, PhD, VistaGen's President and Chief Scientific Officer, stated, "These data demonstrate that we have substantially improved our LiverSafe 3D and now have the potential to identify and purify human hepatocytes with more mature functions, as well as provide a novel assay for drugs that effect CYP3A4 enzyme expression, activity and key drug-drug interactions." Dr. Snodgrass continued, "I am excited by the fact that further improvements in our differentiation protocols have enabled our scientists to produce cultures withmore than80% mature hepatocytes … Continue reading

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Pre-clinical research shows promising treatment for diabetic wounds using stem cells

Posted: Published on March 13th, 2013

Mar. 12, 2013 Pre-clinical research has generated some very promising findings using adult stem cells for the treatment of diabetic wounds. The research carried out by scientists at the National University of Ireland Galway, is published in Diabetes, the official journal of the American Diabetes Association. The work showed that a particular type of stem cell, known as the mesenchymal stem cell (MSC), could increase wound healing when applied together with a biomaterial made from collagen. Diabetic patients have an impaired ability to heal wounds and there is a critical need to develop new treatments to improve healing particularly in patients with foot ulcers. In fact, foot ulceration will affect up to 25% of people suffering from diabetes during their lives and may result in amputation. For the past number of years, lead-author on the research paper Dr Aonghus OLoughlin has been funded by Molecular Medicine Ireland to work in the Regenerative Medicine Institute (REMEDI) at National University of Ireland Galway and Galway University Hospitals. He collaborates with Professor Timothy OBrien, Director of REMEDI, to develop new ways to increase healing of diabetic wounds. Professor OBrien, principal investigator on the research project, said: This data will now allow us proceed … Continue reading

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World's First Three-Parent Monkeys Created

Posted: Published on March 13th, 2013

The finding could fundamentally change how we look at human stem cell tech: If chimeric monkeys require totipotent cells before they can come into being, it stands to reason that human embryonic stem cell therapy might also require totipotent stem cells to render cures. Indeed, the find suggests that testing human therapies on mice and other mammalian species may have sent us down the garden path. The Chimeric Advantage The ability to create chimera from stem cells not only in mice but in other animals, including primates, could prove to be a major advance in biomedical science. In a 2009 study, University of Georgia at Athens cloning expert Steve Stice created 29 chimeric piglets by injecting pluripotent stem cells into pig embryos before implanting them into a surrogate womb. Although it wasnt the first time chimeric pigs were created, it was the first time they came about using cloned pluripotent cells. And because pigs are genetically closer to humans than mice are, success in creating chimeric pigs from stem cells offered renewed hope that the technology could lead to better pharmaceutical testing or stem cell therapies. Mitalipov couldnt agree more. Stem cell therapies hold great promise, he says, from possible … Continue reading

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Nuvilex, Inc. Cell -in-a-Box Technology Could Revitalize the Stem Cell Phenomenon

Posted: Published on March 13th, 2013

NEW YORK, NY--(Marketwire - Mar 12, 2013) - Nuvilex, Inc. ( OTCQB : NVLX ), an international biotech company, could dramatically shift the stem cell conversation with its Cell-in-a-Box technology. Remember not so long ago when every science related conversation seemed to weave its way into a conversation about stem cells? Back around 2007, there was a real phenomenon going on among biotechnology companies that had anything at all to do with stem cells, and now six years later with more research in the books, that enthusiasm has waned a bit. Still, stem cell treatments are being developed for many ailments including heart damage, arthritis, "joint" injuries, neurologic diseases such as Parkinson's, Alzheimer's, ALS, dementia, and even wound repair, among a host of others. However, progress with the development of stem cell-based therapies has been tempered somewhat, largely because of the characteristics of the stem cells themselves. The way the process is supposed to work is that stem cells or other therapeutic cells are implanted or injected into a patient's body to enable the cells' therapeutic action. This therapeutic action can be achieved by the cells producing a "beneficial" healing factor, or by "signaling" to other cells and stimulating healing. … Continue reading

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Painkillers Could Prove Helpful in Stem – Cell Transplants

Posted: Published on March 13th, 2013

Inhibition of a prostaglandin with non-steroidal anti-inflammatory drugs (NSAIDS, such as ibuprofen, acetaminophen and naproxen) has been found to cause stem cells to leave marrow, where they could be harvested for patients with blood disorders By Thea Cunningham and Nature magazine Bone marrow such as this being prepared for a transplant might be easier to extract with the help of aspirin-like drugs. Image: Tino Soriano/National Geographic Society/Corbis Aspirin-like drugs could improve the success of stem-cell transplants for patients with blood or bone-marrow disorders, a study suggests. The compounds coax stem cells from bone marrow into the bloodstream where they can be harvested for use in transplantation and they do so with fewer side effects than drugs now in use. For patients with blood disorders such as leukemia, multiple myeloma or non-Hodgkins lymphoma, transplantation of haematopoietic stem cells precursor cells that reside in the bone marrow and give rise to all types of blood cell can be an effective treatment. Previous work has shown that prostaglandin E2, or PGE2, a lipid known to regulate multiple bodily reactions including pain, fever and inflammation, also has a role in keeping stem cells in the bone marrow. In the latest study, researchers show that … Continue reading

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